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Schema
>
BlackBoxEvent
>
Entries
Some HSPGs are secreted to the plasma membrane
Show undefined attributes
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authored
[InstanceEdit:2024092] Jassal, B, 2011-12-14
category
omitted
compartment
[Compartment:17963] Golgi lumen
[Compartment:876] plasma membrane
created
[InstanceEdit:2024092] Jassal, B, 2011-12-14
dbId
2024108
displayName
Some HSPGs are secreted to the plasma membrane
edited
[InstanceEdit:2024092] Jassal, B, 2011-12-14
eventOf
[Pathway:R-HSA-2022928] HS-GAG biosynthesis - Homo sapiens
followingEvent
[Reaction:R-HSA-1678694] Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans - Homo sapiens
[BlackBoxEvent:R-HSA-2024084] HS-GAGs translocate to the lysosome for degradation - Homo sapiens
input
[DefinedSet:R-HSA-2076619] HSPGs [Golgi lumen]
isChimeric
false
isInDisease
false
isInferred
false
literatureReference
[LiteratureReference:1666986] Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions
modified
[InstanceEdit:10740525] Wright, Adam, 2024-03-08
name
Some HSPGs are secreted to the plasma membrane
orthologousEvent
[BlackBoxEvent:R-CEL-2024108] Some HSPGs are secreted to the plasma membrane - Caenorhabditis elegans
[BlackBoxEvent:R-DME-2024108] Some HSPGs are secreted to the plasma membrane - Drosophila melanogaster
[BlackBoxEvent:R-GGA-2024108] Some HSPGs are secreted to the plasma membrane - Gallus gallus
[BlackBoxEvent:R-XTR-2024108] Some HSPGs are secreted to the plasma membrane - Xenopus tropicalis
[BlackBoxEvent:R-DRE-2024108] Some HSPGs are secreted to the plasma membrane - Danio rerio
[BlackBoxEvent:R-SSC-2024108] Some HSPGs are secreted to the plasma membrane - Sus scrofa
[BlackBoxEvent:R-BTA-2024108] Some HSPGs are secreted to the plasma membrane - Bos taurus
[BlackBoxEvent:R-CFA-2024108] Some HSPGs are secreted to the plasma membrane - Canis familiaris
[BlackBoxEvent:R-RNO-2024108] Some HSPGs are secreted to the plasma membrane - Rattus norvegicus
[BlackBoxEvent:R-MMU-2024108] Some HSPGs are secreted to the plasma membrane - Mus musculus
output
[DefinedSet:R-HSA-2076618] HSPGs [plasma membrane]
precedingEvent
[Reaction:R-HSA-2022860] NDST1-4 can sulfate a glucosamine residue in heparan to form heparan sulfate (HS) - Homo sapiens
[Reaction:R-HSA-2024100] GLCE epimerises GlcA to IdoA - Homo sapiens
[Reaction:R-HSA-2076371] GLCE epimerises more GlcA to IdoA as sulfate content rises - Homo sapiens
[Reaction:R-HSA-2076508] HS2ST1 sulfates IdoA at C2 in heparan sulfate - Homo sapiens
[Reaction:R-HSA-2076383] HS3ST1 sulfates GlcN at C3 in heparan sulfate - Homo sapiens
[Reaction:R-HSA-2076611] HS3STs sulfate GlcN at C3 in heparan sulfate - Homo sapiens
[Reaction:R-HSA-2076419] HS6STs sulfate GlcN at C6 in heparan sulfate/heparin - Homo sapiens
releaseDate
2012-06-12
reviewStatus
[ReviewStatus:9821382] five stars
reviewed
[InstanceEdit:2172129] D'Eustachio, P, 2012-03-28
schemaClass
BlackBoxEvent
species
[Species:48887] Homo sapiens
stId
R-HSA-2024108
summation
[Summation:2024087] Depending on the nature of the core protein HS-GAGs are atta...
Referrals
(precedingEvent)
[Reaction:R-HSA-1678694] Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans
[BlackBoxEvent:R-HSA-2024084] HS-GAGs translocate to the lysosome for degradation
(hasEvent)
[Pathway:R-HSA-2022928] HS-GAG biosynthesis
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