Reactome | FRS2 [plasma membrane]

Schema > EntityWithAccessionedSequence > Entries

FRS2 [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
componentOf	[Complex:R-HSA-5655299] Activated FGFR4 mutants:FRS2 [plasma membrane] - Homo sapiens [Complex:R-HSA-8855579] 2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] - Homo sapiens
consumedByEvent	[Reaction:R-HSA-5655262] Activated FGFR3 point, translocation and fusion mutants bind FRS2 - Homo sapiens [Reaction:R-HSA-5655351] Activated FGFR4 mutants bind FRS2 - Homo sapiens [Reaction:R-HSA-5655339] Activated FGFR2 mutants bind FRS2 - Homo sapiens [Reaction:R-HSA-5655269] Activated FGFR1 mutants bind FRS2 - Homo sapiens [Reaction:R-HSA-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 - Homo sapiens [Reaction:R-HSA-5654422] Activated FGFR4 binds FRS2 - Homo sapiens [Reaction:R-HSA-5654569] Activated FGFR1 binds FRS2 - Homo sapiens [Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 - Homo sapiens [Reaction:R-HSA-5654399] Activated FGFR2 binds FRS2 - Homo sapiens
created	[InstanceEdit:170962] Jassal, B, 2006-01-25 09:51:21
dbId	170963
displayName	FRS2 [plasma membrane]
endCoordinate	508
inDisease	false
inferredTo	[EntityWithAccessionedSequence:R-MMU-170963] Frs2 [plasma membrane] - Mus musculus [EntityWithAccessionedSequence:R-RNO-170963] Frs2 [plasma membrane] - Rattus norvegicus [EntityWithAccessionedSequence:R-CFA-170963] FRS2 [plasma membrane] - Canis familiaris [EntityWithAccessionedSequence:R-BTA-170963] FRS2 [plasma membrane] - Bos taurus [EntityWithAccessionedSequence:R-SSC-170963] FRS2 [plasma membrane] - Sus scrofa [EntityWithAccessionedSequence:R-DRE-170963] frs2b [plasma membrane] - Danio rerio [EntityWithAccessionedSequence:R-XTR-170963] frs2 [plasma membrane] - Xenopus tropicalis [EntityWithAccessionedSequence:R-GGA-170963] FRS2 [plasma membrane] - Gallus gallus [EntityWithAccessionedSequence:R-DME-170963] Dmel\CG13398 [plasma membrane] - Drosophila melanogaster [EntityWithAccessionedSequence:R-CEL-170963] rog-1 [plasma membrane] - Caenorhabditis elegans
maxDepth	1
memberOf	[CandidateSet:R-HSA-9696296] RND1 effectors [cytosol] - Homo sapiens [CandidateSet:R-HSA-9696290] RND2 effectors [cytosol] - Homo sapiens
modified	[InstanceEdit:3622465] Rothfels, K, 2013-05-24
name	FRS2 FRS2-alpha
referenceEntity	[ReferenceGeneProduct:uniprot:Q8WU20] UniProt:Q8WU20 FRS2
referenceType	ReferenceGeneProduct
schemaClass	EntityWithAccessionedSequence
species	[Species:48887] Homo sapiens
stId	R-HSA-170963
startCoordinate	1
updateTrackers	[UpdateTracker:9886365] Update Tracker - [EntityWithAccessionedSequence:170963] FRS2 [plasma membrane] - v45:[addName, modifyEndCoordinate]

Referrals

(updatedInstance)	[UpdateTracker:9886365] Update Tracker - [EntityWithAccessionedSequence:170963] FRS2 [plasma membrane] - v45:[addName, modifyEndCoordinate]
(hasMember)	[CandidateSet:R-HSA-9696290] RND2 effectors [cytosol] [CandidateSet:R-HSA-9696296] RND1 effectors [cytosol] [DefinedSet:R-HSA-191476] FRS2,3 [plasma membrane]
(hasComponent)	[Complex:R-HSA-5655299] Activated FGFR4 mutants:FRS2 [plasma membrane] [Complex:R-HSA-5655257] Activated FGFR2 mutants:FRS2 [plasma membrane] [Complex:R-HSA-5655312] Activated FGFR3 point, translocation and fusion mutants:FRS2 [plasma membrane] [Complex:R-HSA-5655296] Activated FGFR1 mutants:FRS2 [plasma membrane] [Complex:R-HSA-8855579] 2x p-5Y-RET:GDNF:GFRA complexes:FRS2 [plasma membrane] [Complex:R-HSA-5654182] Activated FGFR4:FRS2 [plasma membrane] [Complex:R-HSA-5654176] Activated FGFR1:FRS2 [plasma membrane] [Complex:R-HSA-5654180] Activated FGFR3:FRS2 [plasma membrane] [Complex:R-HSA-5654178] Activated FGFR2:FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5655351] Activated FGFR4 mutants bind FRS2 [Reaction:R-HSA-5655339] Activated FGFR2 mutants bind FRS2 [Reaction:R-HSA-5655262] Activated FGFR3 point, translocation and fusion mutants bind FRS2 [Reaction:R-HSA-5655269] Activated FGFR1 mutants bind FRS2 [Reaction:R-HSA-8855564] 2x p-5Y-RET:GDNF:GFRA complexes bind FRS2 [Reaction:R-HSA-5654422] Activated FGFR4 binds FRS2 [Reaction:R-HSA-5654569] Activated FGFR1 binds FRS2 [Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 [Reaction:R-HSA-5654399] Activated FGFR2 binds FRS2

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