Reactome | Activated FGFR2:FRS2 [plasma membrane]

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Activated FGFR2:FRS2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654396] protein tyrosine kinase activity of Activated FGFR2:FRS2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-5654562] Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 - Homo sapiens [Reaction:R-HSA-5654397] Activated FGFR2 phosphorylates FRS2 - Homo sapiens
created	[InstanceEdit:5654179] Rothfels, Karen, 2014-12-03
dbId	5654178
displayName	Activated FGFR2:FRS2 [plasma membrane]
hasComponent	[DefinedSet:R-HSA-5654152] Activated FGFR2 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-170963] FRS2 [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-5654178] Activated FGFR2:FRS2 [plasma membrane] - Mus musculus [Complex:R-RNO-5654178] Activated FGFR2:FRS2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5654178] Activated FGFR2:FRS2 [plasma membrane] - Canis familiaris [Complex:R-BTA-5654178] Activated FGFR2:FRS2 [plasma membrane] - Bos taurus [Complex:R-DRE-5654178] Activated FGFR2:FRS2 [plasma membrane] - Danio rerio [Complex:R-XTR-5654178] Activated FGFR2:FRS2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5654178] Activated FGFR2:FRS2 [plasma membrane] - Gallus gallus [Complex:R-DME-5654178] Activated FGFR2:FRS2 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-5654178] Activated FGFR2:FRS2 [plasma membrane] - Caenorhabditis elegans
maxDepth	6
name	Activated FGFR2:FRS2
producedByEvent	[Reaction:R-HSA-5654399] Activated FGFR2 binds FRS2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5654178
updateTrackers	[UpdateTracker:9893817] Update Tracker - [Complex:5654178] Activated FGFR2:FRS2 [plasma membrane] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9893817] Update Tracker - [Complex:5654178] Activated FGFR2:FRS2 [plasma membrane] - v56:[updateContainedComponent]
(normalEntity)	[EntityFunctionalStatus:5655264] gain_of_function of Activated FGFR2 mutants:FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5654562] Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 [Reaction:R-HSA-5654397] Activated FGFR2 phosphorylates FRS2
(output)	[Reaction:R-HSA-5654399] Activated FGFR2 binds FRS2
(physicalEntity)	[CatalystActivity:5654396] protein tyrosine kinase activity of Activated FGFR2:FRS2 [plasma membrane]

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