Reactome | Activated FGFR3:FRS2 [plasma membrane]

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Activated FGFR3:FRS2 [plasma membrane] Show undefined attributes

catalystActivities	[CatalystActivity:5654411] protein tyrosine kinase activity of Activated FGFR3:FRS2 [plasma membrane]
compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-HSA-5654565] Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 - Homo sapiens [Reaction:R-HSA-5654408] Activated FGFR3 phosphorylates FRS2 - Homo sapiens
created	[InstanceEdit:5654181] Rothfels, Karen, 2014-12-03
dbId	5654180
displayName	Activated FGFR3:FRS2 [plasma membrane]
hasComponent	[DefinedSet:R-HSA-5654146] Activated FGFR3 [plasma membrane] [EntityWithAccessionedSequence:R-HSA-170963] FRS2 [plasma membrane]
inDisease	false
inferredTo	[Complex:R-MMU-5654180] Activated FGFR3:FRS2 [plasma membrane] - Mus musculus [Complex:R-RNO-5654180] Activated FGFR3:FRS2 [plasma membrane] - Rattus norvegicus [Complex:R-CFA-5654180] Activated FGFR3:FRS2 [plasma membrane] - Canis familiaris [Complex:R-BTA-5654180] Activated FGFR3:FRS2 [plasma membrane] - Bos taurus [Complex:R-DRE-5654180] Activated FGFR3:FRS2 [plasma membrane] - Danio rerio [Complex:R-XTR-5654180] Activated FGFR3:FRS2 [plasma membrane] - Xenopus tropicalis [Complex:R-GGA-5654180] Activated FGFR3:FRS2 [plasma membrane] - Gallus gallus [Complex:R-DME-5654180] Activated FGFR3:FRS2 [plasma membrane] - Drosophila melanogaster [Complex:R-CEL-5654180] Activated FGFR3:FRS2 [plasma membrane] - Caenorhabditis elegans
maxDepth	5
name	Activated FGFR3:FRS2
producedByEvent	[Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2 - Homo sapiens
schemaClass	Complex
species	[Species:48887] Homo sapiens
stId	R-HSA-5654180
updateTrackers	[UpdateTracker:9893937] Update Tracker - [Complex:5654180] Activated FGFR3:FRS2 [plasma membrane] - v56:[updateContainedComponent]

Referrals

(updatedInstance)	[UpdateTracker:9893937] Update Tracker - [Complex:5654180] Activated FGFR3:FRS2 [plasma membrane] - v56:[updateContainedComponent]
(normalEntity)	[EntityFunctionalStatus:5655239] gain_of_function of Activated FGFR3 point, translocation and fusion mutants:FRS2 [plasma membrane]
(input)	[Reaction:R-HSA-5654565] Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2 [Reaction:R-HSA-5654408] Activated FGFR3 phosphorylates FRS2
(output)	[Reaction:R-HSA-5654409] Activated FGFR3 binds FRS2
(physicalEntity)	[CatalystActivity:5654411] protein tyrosine kinase activity of Activated FGFR3:FRS2 [plasma membrane]

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