Reactome | Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC

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Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	binding
compartment	[Compartment:7660] nucleoplasm [Compartment:13231] nuclear envelope
created	[InstanceEdit:165042] Matthews, L, 2005-07-26 23:04:06
dbId	165043
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC
edited	[InstanceEdit:182779] Matthews, L, 2006-07-13 06:31:19
eventOf	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA - Homo sapiens
followingEvent	[Reaction:R-HSA-165047] Translocation of nuclear RNA transport complex to cytoplasm - Homo sapiens
input	[Complex:R-HSA-157689] Nuclear Pore Complex (NPC) [nuclear envelope] [Complex:R-HSA-165537] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:6787490] Structural basis for cooperative RNA binding and export complex assembly by HIV Rev [LiteratureReference:167644] The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC
output	[Complex:R-HSA-165531] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP:NPC [nuclear envelope]
precedingEvent	[Reaction:R-HSA-165034] Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-06-13
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192365] Kumar, A, 2007-01-31 22:47:49
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-165043
summation	[Summation:179157] The Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP complex assoc...

Referrals

(hasEvent)	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA
(precedingEvent)	[Reaction:R-HSA-165047] Translocation of nuclear RNA transport complex to cytoplasm

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