Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC

Stable Identifier
R-HSA-165043
Type
Reaction [binding]
Species
Homo sapiens
Related Species
Human immunodeficiency virus 1
Compartment
nucleoplasm, nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP complex associates with the NPC (Askjaer et al. 1998; Daugherty et al. 2010).
Literature References
PubMed ID Title Journal Year
9837918 The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP

Jensen, TH, Englmeier, L, Nilsson, J, Askjaer, P, Kjems, J

J Biol Chem 1998
20953181 Structural basis for cooperative RNA binding and export complex assembly by HIV Rev

Daugherty, MD, Liu, B, Frankel, AD

Nat. Struct. Mol. Biol. 2010
Participants
Input
Output
Participates
as an event of
Disease
Name Identifier Synonyms
Human immunodeficiency virus infectious disease DOID:526 HIV infection
Authored
Matthews, L  (2005-07-27)
Rice, AP  (2005-07-27)
Reviewed
Kumar, A  (2007-02-01)
Created
Matthews, L  (2005-07-27)
Cite Us!