Reactome | Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP

Schema > Reaction > Entries

Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP Show undefined attributes

authored	[InstanceEdit:165064] Matthews, L, Rice, AP, 2005-07-27 00:00:00
category	binding
compartment	[Compartment:7660] nucleoplasm
created	[InstanceEdit:165042] Matthews, L, 2005-07-26 23:04:06
dbId	165034
disease	[Disease:1660559] Human immunodeficiency virus infectious disease
displayName	Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP
edited	[InstanceEdit:182365] Matthews, L, 2006-07-07 14:08:37
eventOf	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA - Homo sapiens
followingEvent	[Reaction:R-HSA-165043] Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC - Homo sapiens
input	[Complex:R-HSA-180738] RAN:GTP [nucleoplasm] [Complex:R-HSA-180873] Rev multimer-bound HIV-1 mRNA:CRM1 complex [nucleoplasm]
isInDisease	true
isInferred	false
literatureReference	[LiteratureReference:167644] The specificity of the CRM1-Rev nuclear export signal interaction is mediated by RanGTP
modified	[InstanceEdit:9830342] Matthews, Lisa, 2023-03-08
name	Rev multimer-bound HIV mRNA:CRM1 complex associates with Ran:GTP
output	[Complex:R-HSA-165537] Rev multimer-bound HIV-1 mRNA:Crm1:Ran:GTP [nucleoplasm]
precedingEvent	[Reaction:R-HSA-165033] Multimerization of Rev - Homo sapiens [Reaction:R-HSA-180687] Conversion of Ran-GDP to Ran-GTP - Homo sapiens
relatedSpecies	[Species:164493] Human immunodeficiency virus 1
releaseDate	2005-04-11
requiredInputComponent	[EntityWithAccessionedSequence:R-HSA-165529] XPO1 [nucleoplasm] - Homo sapiens
reviewStatus	[ReviewStatus:9821382] five stars
reviewed	[InstanceEdit:192365] Kumar, A, 2007-01-31 22:47:49
schemaClass	Reaction
species	[Species:48887] Homo sapiens
stId	R-HSA-165034
summation	[Summation:169716] RanGTP binds to a preformed Rev-CRM1 complex.

Referrals

(hasEvent)	[Pathway:R-HSA-165054] Rev-mediated nuclear export of HIV RNA
(precedingEvent)	[Reaction:R-HSA-165043] Rev multimer-bound HIV mRNA:Crm1:Ran:GTP complex associates with the NPC

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