Reactome | CERA [plasma membrane]

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CERA [plasma membrane] Show undefined attributes

compartment	[Compartment:876] plasma membrane
consumedByEvent	[Reaction:R-DDI-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Dictyostelium discoideum [Reaction:R-DME-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Drosophila melanogaster [Reaction:R-XTR-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Xenopus tropicalis [Reaction:R-DRE-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Danio rerio [Reaction:R-SSC-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Sus scrofa [Reaction:R-BTA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Bos taurus [Reaction:R-CFA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Canis familiaris [Reaction:R-RNO-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Rattus norvegicus [Reaction:R-MMU-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Mus musculus [Reaction:R-HSA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) - Homo sapiens [Reaction:R-CEL-1638845] CERK phosphorylates CERA to form C1P - Caenorhabditis elegans [Reaction:R-DME-1638845] CERK phosphorylates CERA to form C1P - Drosophila melanogaster [Reaction:R-GGA-1638845] CERK phosphorylates CERA to form C1P - Gallus gallus [Reaction:R-XTR-1638845] CERK phosphorylates CERA to form C1P - Xenopus tropicalis [Reaction:R-DRE-1638845] CERK phosphorylates CERA to form C1P - Danio rerio [Reaction:R-SSC-1638845] CERK phosphorylates CERA to form C1P - Sus scrofa [Reaction:R-BTA-1638845] CERK phosphorylates CERA to form C1P - Bos taurus [Reaction:R-CFA-1638845] CERK phosphorylates CERA to form C1P - Canis familiaris [Reaction:R-RNO-1638845] CERK phosphorylates CERA to form C1P - Rattus norvegicus [Reaction:R-MMU-1638845] CERK phosphorylates CERA to form C1P - Mus musculus [Reaction:R-HSA-1638845] CERK phosphorylates CERA to form C1P - Homo sapiens [Reaction:R-PFA-429786] SGMS2 transfers phosphocholine onto ceramide - Plasmodium falciparum [Reaction:R-HSA-429786] SGMS2 transfers phosphocholine onto ceramide - Homo sapiens [Reaction:R-MMU-429786] SGMS2 transfers phosphocholine onto ceramide - Mus musculus [Reaction:R-RNO-429786] SGMS2 transfers phosphocholine onto ceramide - Rattus norvegicus [Reaction:R-CFA-429786] SGMS2 transfers phosphocholine onto ceramide - Canis familiaris [Reaction:R-BTA-429786] SGMS2 transfers phosphocholine onto ceramide - Bos taurus [Reaction:R-SSC-429786] SGMS2 transfers phosphocholine onto ceramide - Sus scrofa [Reaction:R-DRE-429786] SGMS2 transfers phosphocholine onto ceramide - Danio rerio [Reaction:R-XTR-429786] SGMS2 transfers phosphocholine onto ceramide - Xenopus tropicalis [Reaction:R-GGA-429786] SGMS2 transfers phosphocholine onto ceramide - Gallus gallus [Reaction:R-CEL-429786] SGMS2 transfers phosphocholine onto ceramide - Caenorhabditis elegans
created	[InstanceEdit:429791] D'Eustachio, P, 2009-07-21
dbId	429807
displayName	CERA [plasma membrane]
inDisease	false
maxDepth	1
memberOf	[DefinedSet:R-ALL-5696348] CERA,PE,PS [plasma membrane] [DefinedSet:R-ALL-9850728] GSL [plasma membrane]
modified	[InstanceEdit:9841226] Stephan, Ralf, 2023-08-11
name	CERA ceramide
producedByEvent	[Reaction:R-SCE-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Saccharomyces cerevisiae [Reaction:R-SPO-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Schizosaccharomyces pombe [Reaction:R-HSA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Homo sapiens [Reaction:R-MMU-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Mus musculus [Reaction:R-RNO-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Rattus norvegicus [Reaction:R-CFA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Canis familiaris [Reaction:R-BTA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Bos taurus [Reaction:R-SSC-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Sus scrofa [Reaction:R-DRE-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Danio rerio [Reaction:R-GGA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Gallus gallus [Reaction:R-DME-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Drosophila melanogaster [Reaction:R-CEL-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Caenorhabditis elegans [Reaction:R-DDI-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) - Dictyostelium discoideum [Reaction:R-HSA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Homo sapiens [Reaction:R-MMU-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Mus musculus [Reaction:R-MMU-1640164] ENPP7 hydrolyzes sphingomyelin - Mus musculus [Reaction:R-HSA-1640164] ENPP7 hydrolyzes sphingomyelin - Homo sapiens [Reaction:R-RNO-1640164] ENPP7 hydrolyzes sphingomyelin - Rattus norvegicus [Reaction:R-RNO-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Rattus norvegicus [Reaction:R-CFA-1640164] ENPP7 hydrolyzes sphingomyelin - Canis familiaris [Reaction:R-CFA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Canis familiaris [Reaction:R-BTA-1640164] ENPP7 hydrolyzes sphingomyelin - Bos taurus [Reaction:R-BTA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Bos taurus [Reaction:R-SSC-1640164] ENPP7 hydrolyzes sphingomyelin - Sus scrofa [Reaction:R-SSC-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Sus scrofa [Reaction:R-DRE-1640164] ENPP7 hydrolyzes sphingomyelin - Danio rerio [Reaction:R-DRE-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Danio rerio [Reaction:R-XTR-1640164] ENPP7 hydrolyzes sphingomyelin - Xenopus tropicalis [Reaction:R-XTR-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Xenopus tropicalis [Reaction:R-GGA-1640164] ENPP7 hydrolyzes sphingomyelin - Gallus gallus [Reaction:R-GGA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Gallus gallus [Reaction:R-CEL-1640164] ENPP7 hydrolyzes sphingomyelin - Caenorhabditis elegans [Reaction:R-CEL-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Caenorhabditis elegans [Reaction:R-DDI-1640164] ENPP7 hydrolyzes sphingomyelin - Dictyostelium discoideum [Reaction:R-SPO-1640164] ENPP7 hydrolyzes sphingomyelin - Schizosaccharomyces pombe [Reaction:R-SCE-1640164] ENPP7 hydrolyzes sphingomyelin - Saccharomyces cerevisiae [Reaction:R-DME-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Drosophila melanogaster [Reaction:R-DDI-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) - Dictyostelium discoideum
referenceEntity	[ReferenceMolecule:chebi:83273] N-acylsphingoid [ChEBI:83273]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-429807
updateTrackers	[UpdateTracker:9906181] Update Tracker - [SimpleEntity:429807] CERA [plasma membrane] - v86:[add_removeReferenceEntity] [UpdateTracker:9871373] Update Tracker - [SimpleEntity:429807] CERA [plasma membrane] - v39:[addName]

Referrals

(input)	[Reaction:R-CEL-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-DME-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-GGA-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-XTR-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-DRE-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-SSC-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-BTA-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-CFA-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-RNO-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-MMU-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-HSA-1638845] CERK phosphorylates CERA to form C1P [Reaction:R-DDI-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-DME-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-XTR-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-DRE-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-SSC-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-BTA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-CFA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-RNO-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-MMU-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-HSA-1606583] ASAH2 hydrolyzes ceramide (plasma membrane) [Reaction:R-PFA-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-HSA-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-MMU-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-RNO-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-CFA-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-BTA-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-SSC-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-DRE-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-XTR-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-GGA-429786] SGMS2 transfers phosphocholine onto ceramide [Reaction:R-CEL-429786] SGMS2 transfers phosphocholine onto ceramide
(output)	[Reaction:R-SCE-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-SPO-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-HSA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-MMU-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-RNO-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-CFA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-BTA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-SSC-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-DRE-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-GGA-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-DME-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-CEL-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-DDI-1861788] GBA2 hydrolyzes GlcCer (plasma membrane) [Reaction:R-HSA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-MMU-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-MMU-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-HSA-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-RNO-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-RNO-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-CFA-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-CFA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-BTA-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-BTA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-SSC-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-SSC-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-DRE-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-DRE-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-XTR-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-XTR-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-GGA-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-GGA-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-CEL-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-CEL-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-DDI-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-SPO-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-SCE-1640164] ENPP7 hydrolyzes sphingomyelin [Reaction:R-DME-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane) [Reaction:R-DDI-1606273] SMPD2 and 3 hydrolyze sphingomyelin (plasma membrane)
(hasMember)	[DefinedSet:R-ALL-5696348] CERA,PE,PS [plasma membrane] [DefinedSet:R-ALL-9850728] GSL [plasma membrane]
(updatedInstance)	[UpdateTracker:9906181] Update Tracker - [SimpleEntity:429807] CERA [plasma membrane] - v86:[add_removeReferenceEntity] [UpdateTracker:9871373] Update Tracker - [SimpleEntity:429807] CERA [plasma membrane] - v39:[addName]

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