Reactome | E1 [cytosol]

Schema > SimpleEntity > Entries

E1 [cytosol] Show undefined attributes

compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-804969] HSD17B1 hydrogenates E1 to EST17b - Homo sapiens [Reaction:R-MMU-804969] HSD17B1 hydrogenates E1 to EST17b - Mus musculus [Reaction:R-RNO-804969] HSD17B1 hydrogenates E1 to EST17b - Rattus norvegicus [Reaction:R-CFA-804969] HSD17B1 hydrogenates E1 to EST17b - Canis familiaris [Reaction:R-BTA-804969] HSD17B1 hydrogenates E1 to EST17b - Bos taurus [Reaction:R-SSC-804969] HSD17B1 hydrogenates E1 to EST17b - Sus scrofa [Reaction:R-DRE-804969] HSD17B1 hydrogenates E1 to EST17b - Danio rerio [Reaction:R-XTR-804969] HSD17B1 hydrogenates E1 to EST17b - Xenopus tropicalis [Reaction:R-GGA-804969] HSD17B1 hydrogenates E1 to EST17b - Gallus gallus [Reaction:R-DDI-804969] HSD17B1 hydrogenates E1 to EST17b - Dictyostelium discoideum [Reaction:R-SPO-804969] HSD17B1 hydrogenates E1 to EST17b - Schizosaccharomyces pombe
created	[InstanceEdit:193053] Jassal, B, 2007-02-13 10:16:33
crossReference	[DatabaseIdentifier:30202] COMPOUND:C00468
dbId	193066
displayName	E1 [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9968069] D'Eustachio, Peter, 2025-10-08
name	E1 estrone
producedByEvent	[Reaction:R-SPO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Schizosaccharomyces pombe [Reaction:R-DME-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Drosophila melanogaster [Reaction:R-GGA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Gallus gallus [Reaction:R-XTR-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Xenopus tropicalis [Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Homo sapiens [Reaction:R-MMU-5693390] HSD17B11 dehydrogenates EST17b to E1 - Mus musculus [Reaction:R-RNO-5693390] HSD17B11 dehydrogenates EST17b to E1 - Rattus norvegicus [Reaction:R-CFA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Canis familiaris [Reaction:R-BTA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Bos taurus [Reaction:R-SSC-5693390] HSD17B11 dehydrogenates EST17b to E1 - Sus scrofa [Reaction:R-XTR-5693390] HSD17B11 dehydrogenates EST17b to E1 - Xenopus tropicalis [Reaction:R-GGA-5693390] HSD17B11 dehydrogenates EST17b to E1 - Gallus gallus [Reaction:R-DME-5693390] HSD17B11 dehydrogenates EST17b to E1 - Drosophila melanogaster [Reaction:R-CEL-5693390] HSD17B11 dehydrogenates EST17b to E1 - Caenorhabditis elegans [Reaction:R-SCE-5693390] HSD17B11 dehydrogenates EST17b to E1 - Saccharomyces cerevisiae [Reaction:R-HSA-193060] CYP19A1 hydroxylates ANDST to E1 - Homo sapiens [Reaction:R-MMU-193060] CYP19A1 hydroxylates ANDST to E1 - Mus musculus [Reaction:R-RNO-193060] CYP19A1 hydroxylates ANDST to E1 - Rattus norvegicus [Reaction:R-CFA-193060] CYP19A1 hydroxylates ANDST to E1 - Canis familiaris [Reaction:R-BTA-193060] CYP19A1 hydroxylates ANDST to E1 - Bos taurus [Reaction:R-SSC-193060] CYP19A1 hydroxylates ANDST to E1 - Sus scrofa [Reaction:R-DRE-193060] CYP19A1 hydroxylates ANDST to E1 - Danio rerio [Reaction:R-XTR-193060] CYP19A1 hydroxylates ANDST to E1 - Xenopus tropicalis [Reaction:R-GGA-193060] CYP19A1 hydroxylates ANDST to E1 - Gallus gallus [Reaction:R-DME-193060] CYP19A1 hydroxylates ANDST to E1 - Drosophila melanogaster [Reaction:R-CEL-193060] CYP19A1 hydroxylates ANDST to E1 - Caenorhabditis elegans [Reaction:R-HSA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Homo sapiens [Reaction:R-MMU-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Mus musculus [Reaction:R-RNO-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Rattus norvegicus [Reaction:R-BTA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Bos taurus [Reaction:R-DRE-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Danio rerio [Reaction:R-XTR-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) - Xenopus tropicalis [Reaction:R-HSA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Homo sapiens [Reaction:R-MMU-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Mus musculus [Reaction:R-RNO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Rattus norvegicus [Reaction:R-CFA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Canis familiaris [Reaction:R-BTA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Bos taurus [Reaction:R-SSC-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) - Sus scrofa
referenceEntity	[ReferenceMolecule:chebi:17263] estrone [ChEBI:17263]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-193066
updateTrackers	[UpdateTracker:9891969] Update Tracker - [SimpleEntity:193066] E1 [cytosol] - v52:[modifyName] [UpdateTracker:9873490] Update Tracker - [SimpleEntity:193066] E1 [cytosol] - v43:[addName]

Referrals

(input)	[Reaction:R-HSA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-MMU-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-RNO-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-CFA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-BTA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-SSC-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-DRE-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-XTR-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-GGA-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-DDI-804969] HSD17B1 hydrogenates E1 to EST17b [Reaction:R-SPO-804969] HSD17B1 hydrogenates E1 to EST17b
(output)	[Reaction:R-SPO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-DME-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-GGA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-XTR-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-HSA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-MMU-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-RNO-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-CFA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-BTA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-SSC-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-XTR-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-GGA-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-DME-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-CEL-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-SCE-5693390] HSD17B11 dehydrogenates EST17b to E1 [Reaction:R-HSA-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-MMU-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-RNO-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-CFA-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-BTA-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-SSC-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-DRE-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-XTR-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-GGA-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-DME-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-CEL-193060] CYP19A1 hydroxylates ANDST to E1 [Reaction:R-HSA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-MMU-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-RNO-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-BTA-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-DRE-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-XTR-6810594] HSD17B14 tetramer oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-HSA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-MMU-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-RNO-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-CFA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-BTA-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1) [Reaction:R-SSC-8862137] HSD17B2 oxidises estradiol (EST17b) to estrone (E1)
(updatedInstance)	[UpdateTracker:9891969] Update Tracker - [SimpleEntity:193066] E1 [cytosol] - v52:[modifyName] [UpdateTracker:9873490] Update Tracker - [SimpleEntity:193066] E1 [cytosol] - v43:[addName]

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