Reactome | O2.- [cytosol]

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O2.- [cytosol] Show undefined attributes

authored	[InstanceEdit:1222281] Stephan, R, 2011-01-10
compartment	[Compartment:70101] cytosol
consumedByEvent	[Reaction:R-HSA-1222462] SodB reduces superoxide to H2O2 - Homo sapiens [Reaction:R-HSA-1222462] SodB reduces superoxide to H2O2 - Homo sapiens [Reaction:R-HSA-1222407] Superoxide and nitric oxide react to peroxynitrite - Homo sapiens [BlackBoxEvent:R-HSA-9709879] BIL scavenges O2.- - Homo sapiens [Reaction:R-HSA-1222469] SodC reduces superoxide to H2O2 - Homo sapiens [Reaction:R-HSA-1222469] SodC reduces superoxide to H2O2 - Homo sapiens [Reaction:R-DRE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Danio rerio [Reaction:R-DRE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Danio rerio [Reaction:R-HSA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Homo sapiens [Reaction:R-HSA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Homo sapiens [Reaction:R-MMU-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Mus musculus [Reaction:R-MMU-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Mus musculus [Reaction:R-RNO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Rattus norvegicus [Reaction:R-RNO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Rattus norvegicus [Reaction:R-CFA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Canis familiaris [Reaction:R-CFA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Canis familiaris [Reaction:R-BTA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Bos taurus [Reaction:R-BTA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Bos taurus [Reaction:R-SSC-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Sus scrofa [Reaction:R-SSC-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Sus scrofa [Reaction:R-XTR-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Xenopus tropicalis [Reaction:R-XTR-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Xenopus tropicalis [Reaction:R-GGA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Gallus gallus [Reaction:R-GGA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Gallus gallus [Reaction:R-DME-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Drosophila melanogaster [Reaction:R-DME-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Drosophila melanogaster [Reaction:R-CEL-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Caenorhabditis elegans [Reaction:R-CEL-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Caenorhabditis elegans [Reaction:R-DDI-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Dictyostelium discoideum [Reaction:R-DDI-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Dictyostelium discoideum [Reaction:R-SPO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Schizosaccharomyces pombe [Reaction:R-SPO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Schizosaccharomyces pombe [Reaction:R-SCE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Saccharomyces cerevisiae [Reaction:R-SCE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) - Saccharomyces cerevisiae [Reaction:R-HSA-1497878] Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-) - Homo sapiens
created	[InstanceEdit:1222482] Jassal, B, 2011-02-28
dbId	1222424
displayName	O2.- [cytosol]
inDisease	false
maxDepth	1
modified	[InstanceEdit:9619952] Wu, G, 2018-09-19
name	O2.- SO2.- superoxide
producedByEvent	[Reaction:R-HSA-6807557] NOX4, NOX5 reduce O2 to O2.- - Homo sapiens [Reaction:R-HSA-6807557] NOX4, NOX5 reduce O2 to O2.- - Homo sapiens [Reaction:R-MMU-6807557] NOX4, NOX5 reduce O2 to O2.- - Mus musculus [Reaction:R-MMU-6807557] NOX4, NOX5 reduce O2 to O2.- - Mus musculus [Reaction:R-RNO-6807557] NOX4, NOX5 reduce O2 to O2.- - Rattus norvegicus [Reaction:R-RNO-6807557] NOX4, NOX5 reduce O2 to O2.- - Rattus norvegicus [Reaction:R-CFA-6807557] NOX4, NOX5 reduce O2 to O2.- - Canis familiaris [Reaction:R-CFA-6807557] NOX4, NOX5 reduce O2 to O2.- - Canis familiaris [Reaction:R-BTA-6807557] NOX4, NOX5 reduce O2 to O2.- - Bos taurus [Reaction:R-BTA-6807557] NOX4, NOX5 reduce O2 to O2.- - Bos taurus [Reaction:R-SSC-6807557] NOX4, NOX5 reduce O2 to O2.- - Sus scrofa [Reaction:R-SSC-6807557] NOX4, NOX5 reduce O2 to O2.- - Sus scrofa [Reaction:R-XTR-6807557] NOX4, NOX5 reduce O2 to O2.- - Xenopus tropicalis [Reaction:R-XTR-6807557] NOX4, NOX5 reduce O2 to O2.- - Xenopus tropicalis [Reaction:R-GGA-6807557] NOX4, NOX5 reduce O2 to O2.- - Gallus gallus [Reaction:R-GGA-6807557] NOX4, NOX5 reduce O2 to O2.- - Gallus gallus [Reaction:R-DME-6807557] NOX4, NOX5 reduce O2 to O2.- - Drosophila melanogaster [Reaction:R-DME-6807557] NOX4, NOX5 reduce O2 to O2.- - Drosophila melanogaster [Reaction:R-DDI-6807557] NOX4, NOX5 reduce O2 to O2.- - Dictyostelium discoideum [Reaction:R-DDI-6807557] NOX4, NOX5 reduce O2 to O2.- - Dictyostelium discoideum [Reaction:R-HSA-6799733] Semiquinone reacts with oxygen - Homo sapiens [Reaction:R-HSA-1222376] NOX2 generates superoxide from oxygen - Homo sapiens [Reaction:R-HSA-1222376] NOX2 generates superoxide from oxygen - Homo sapiens [Reaction:R-MMU-1222376] NOX2 generates superoxide from oxygen - Mus musculus [Reaction:R-MMU-1222376] NOX2 generates superoxide from oxygen - Mus musculus [Reaction:R-RNO-1222376] NOX2 generates superoxide from oxygen - Rattus norvegicus [Reaction:R-RNO-1222376] NOX2 generates superoxide from oxygen - Rattus norvegicus [Reaction:R-CFA-1222376] NOX2 generates superoxide from oxygen - Canis familiaris [Reaction:R-CFA-1222376] NOX2 generates superoxide from oxygen - Canis familiaris [Reaction:R-BTA-1222376] NOX2 generates superoxide from oxygen - Bos taurus [Reaction:R-BTA-1222376] NOX2 generates superoxide from oxygen - Bos taurus [Reaction:R-SSC-1222376] NOX2 generates superoxide from oxygen - Sus scrofa [Reaction:R-SSC-1222376] NOX2 generates superoxide from oxygen - Sus scrofa [Reaction:R-DRE-1222376] NOX2 generates superoxide from oxygen - Danio rerio [Reaction:R-DRE-1222376] NOX2 generates superoxide from oxygen - Danio rerio [Reaction:R-XTR-1222376] NOX2 generates superoxide from oxygen - Xenopus tropicalis [Reaction:R-XTR-1222376] NOX2 generates superoxide from oxygen - Xenopus tropicalis [Reaction:R-GGA-1222376] NOX2 generates superoxide from oxygen - Gallus gallus [Reaction:R-GGA-1222376] NOX2 generates superoxide from oxygen - Gallus gallus [Reaction:R-HSA-1497810] Uncoupled eNOS favours the formation of superoxide - Homo sapiens [Reaction:R-HSA-1497810] Uncoupled eNOS favours the formation of superoxide - Homo sapiens [Reaction:R-MMU-1497810] Uncoupled eNOS favours the formation of superoxide - Mus musculus [Reaction:R-MMU-1497810] Uncoupled eNOS favours the formation of superoxide - Mus musculus [Reaction:R-RNO-1497810] Uncoupled eNOS favours the formation of superoxide - Rattus norvegicus [Reaction:R-RNO-1497810] Uncoupled eNOS favours the formation of superoxide - Rattus norvegicus [Reaction:R-BTA-1497810] Uncoupled eNOS favours the formation of superoxide - Bos taurus [Reaction:R-BTA-1497810] Uncoupled eNOS favours the formation of superoxide - Bos taurus [Reaction:R-DME-1497810] Uncoupled eNOS favours the formation of superoxide - Drosophila melanogaster [Reaction:R-DME-1497810] Uncoupled eNOS favours the formation of superoxide - Drosophila melanogaster [Reaction:R-CEL-1497810] Uncoupled eNOS favours the formation of superoxide - Caenorhabditis elegans [Reaction:R-CEL-1497810] Uncoupled eNOS favours the formation of superoxide - Caenorhabditis elegans [Reaction:R-DDI-1497810] Uncoupled eNOS favours the formation of superoxide - Dictyostelium discoideum [Reaction:R-DDI-1497810] Uncoupled eNOS favours the formation of superoxide - Dictyostelium discoideum [Reaction:R-SPO-1497810] Uncoupled eNOS favours the formation of superoxide - Schizosaccharomyces pombe [Reaction:R-SPO-1497810] Uncoupled eNOS favours the formation of superoxide - Schizosaccharomyces pombe [Reaction:R-SCE-1497810] Uncoupled eNOS favours the formation of superoxide - Saccharomyces cerevisiae [Reaction:R-SCE-1497810] Uncoupled eNOS favours the formation of superoxide - Saccharomyces cerevisiae
referenceEntity	[ReferenceMolecule:chebi:18421] superoxide [ChEBI:18421]
referenceType	ReferenceMolecule
schemaClass	SimpleEntity
stId	R-ALL-1222424
updateTrackers	[UpdateTracker:9891262] Update Tracker - [SimpleEntity:1222424] O2.- [cytosol] - v52:[modifyName]

Referrals

(input)	[BlackBoxEvent:R-HSA-9709879] BIL scavenges O2.- [Reaction:R-HSA-1222462] SodB reduces superoxide to H2O2 [Reaction:R-HSA-1222469] SodC reduces superoxide to H2O2 [Reaction:R-DRE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-HSA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-MMU-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-RNO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-CFA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-BTA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-SSC-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-XTR-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-GGA-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-DME-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-CEL-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-DDI-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-SPO-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-SCE-3299691] SOD1 catalyzes 2H+ + 2O2.- => O2 + H2O2 (cytosol) [Reaction:R-HSA-1222407] Superoxide and nitric oxide react to peroxynitrite [Reaction:R-HSA-1497878] Superoxide reacts rapidly with NO to form peroxynitrite (ONOO-)
(output)	[Reaction:R-HSA-1222376] NOX2 generates superoxide from oxygen [Reaction:R-MMU-1222376] NOX2 generates superoxide from oxygen [Reaction:R-RNO-1222376] NOX2 generates superoxide from oxygen [Reaction:R-CFA-1222376] NOX2 generates superoxide from oxygen [Reaction:R-BTA-1222376] NOX2 generates superoxide from oxygen [Reaction:R-SSC-1222376] NOX2 generates superoxide from oxygen [Reaction:R-DRE-1222376] NOX2 generates superoxide from oxygen [Reaction:R-XTR-1222376] NOX2 generates superoxide from oxygen [Reaction:R-GGA-1222376] NOX2 generates superoxide from oxygen [Reaction:R-HSA-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-MMU-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-RNO-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-CFA-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-BTA-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-SSC-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-XTR-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-GGA-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-DME-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-DDI-6807557] NOX4, NOX5 reduce O2 to O2.- [Reaction:R-HSA-6799733] Semiquinone reacts with oxygen [Reaction:R-HSA-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-MMU-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-RNO-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-BTA-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-DME-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-CEL-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-DDI-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-SPO-1497810] Uncoupled eNOS favours the formation of superoxide [Reaction:R-SCE-1497810] Uncoupled eNOS favours the formation of superoxide
(updatedInstance)	[UpdateTracker:9891262] Update Tracker - [SimpleEntity:1222424] O2.- [cytosol] - v52:[modifyName]

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