Reactome | endopeptidase activity of 26S proteasome [cytosol]

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endopeptidase activity of 26S proteasome [cytosol] Show undefined attributes

activity	[GO_MolecularFunction:1793] endopeptidase activity
catalyzedEvent	[BlackBoxEvent:R-RNO-5687112] MAPK6 is degraded by the 26S proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-450466] AUF1:mRNA complex is degraded - Rattus norvegicus [BlackBoxEvent:R-RNO-9954728] The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide - Rattus norvegicus [BlackBoxEvent:R-RNO-9755303] 26S proteasome degrades HIFalpha - Rattus norvegicus [BlackBoxEvent:R-RNO-5668520] 26Sproteasome degrades K48polyUb-NIK - Rattus norvegicus [BlackBoxEvent:R-RNO-5362448] Hh C-terminal fragments are degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-9934893] Proteolysis of K48polyUb-K,p-S-PER1,2,3 - Rattus norvegicus [BlackBoxEvent:R-RNO-9755306] ub UBXN7 is degraded by the 26S proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-8866553] misfolded CFTR is degraded by the 26S proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-8932355] 26S proteasome degrades Ub-NFE2L2 - Rattus norvegicus [BlackBoxEvent:R-RNO-8957265] 26S proteasome degrades TP73 polyubiquitinated by ITCH - Rattus norvegicus [BlackBoxEvent:R-RNO-5610760] GLI1 is degraded by the proteasome after ubiquitination by ITCH - Rattus norvegicus [BlackBoxEvent:R-RNO-5610758] GLI1 is degraded by the proteasome after ubiquitination by beta-TrCP - Rattus norvegicus [BlackBoxEvent:R-RNO-5635868] ub-GLI is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-5668481] Protesomal degradation of K48polyUb-TRAF3 - Rattus norvegicus [BlackBoxEvent:R-RNO-5607731] 26S proteasome processes p-7S-p100:RELB to form p52:RELB - Rattus norvegicus [BlackBoxEvent:R-RNO-1236970] Proteasomal clevage of exogenous antigen (26S proteasome catalyst) - Rattus norvegicus [BlackBoxEvent:R-RNO-353125] 26S proteosome degrades ODC holoenzyme complex - Rattus norvegicus [Reaction:R-RNO-9929486] SPOP-mediated degradation of CD274 by 26S Proteosome - Rattus norvegicus [Reaction:R-RNO-9931314] Proteasomal degradation of polyUb-p-S195-CD274 - Rattus norvegicus [Reaction:R-RNO-9929352] Ubiquitinated CD274 is degraded by the 26S proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-75825] Proteasome mediated degradation of Cyclin D1 - Rattus norvegicus [BlackBoxEvent:R-RNO-8854071] Proteasome-mediated degradation of PolyUb-FBXL7 - Rattus norvegicus [BlackBoxEvent:R-RNO-8854044] Proteasome degrades AURKA ubiquitinated by SCF-FBXL7 - Rattus norvegicus [BlackBoxEvent:R-RNO-1168640] Ubiquitinated IkB is degraded - Rattus norvegicus [BlackBoxEvent:R-RNO-69016] Ubiquitinated Cdc6 is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-5607724] 26S proteasome processes K48PolyUb-K21,22-p-S32,36-IkBA:NF-kB complex to form NF-kB complex - Rattus norvegicus [BlackBoxEvent:R-RNO-209061] Ubiquitinated and phosphorylated IKBA binds to and is degraded by the proteasome complex - Rattus norvegicus [BlackBoxEvent:R-RNO-5610754] GLI3 is partially degraded by the proteasome to yield the GLI3 repressor - Rattus norvegicus [BlackBoxEvent:R-RNO-9766223] Proteasome-dependent degradation of ubiquitinated CDH1 - Rattus norvegicus [BlackBoxEvent:R-RNO-2130282] Degradation of ubiquitinated beta catenin by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-3640874] Ub-RibC-AXIN is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-4641260] Ubiquitinated DVL1 is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-1504193] Ubiquitinated DVL is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-4641256] Ubiquitinated AXIN is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-4608855] PRICKLE1 is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-5658430] NF1 is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-68948] Ubiquitinated Orc1 is degraded by the proteasome - Rattus norvegicus [BlackBoxEvent:R-RNO-1234159] Proteasome proteolyzes ub-HIF-alpha - Rattus norvegicus [BlackBoxEvent:R-RNO-8850992] Proteasome degrades polyubiquitinated PTEN - Rattus norvegicus [BlackBoxEvent:R-RNO-983150] Proteasomal cleavage of substrate - Rattus norvegicus [BlackBoxEvent:R-RNO-8852354] GTSE1 facilitates proteasome-mediated degradation of TP53 - Rattus norvegicus [BlackBoxEvent:R-RNO-264458] Proteasome mediated degradation of COP1 - Rattus norvegicus [BlackBoxEvent:R-RNO-174255] Degradation multiubiquitinated Cyclin A - Rattus norvegicus [BlackBoxEvent:R-RNO-174105] Degradation of multiubiquitinated cell cycle proteins - Rattus norvegicus [BlackBoxEvent:R-RNO-174203] SCF-mediated degradation of Emi1 - Rattus norvegicus [BlackBoxEvent:R-RNO-174202] Degradation of multiubiquitinated Securin - Rattus norvegicus
created	[InstanceEdit:10102717] Weiser, Joel, 2026-03-16
dbId	10103487
displayName	endopeptidase activity of 26S proteasome [cytosol]
physicalEntity	[Complex:R-RNO-68819] 26S proteasome [cytosol]
schemaClass	CatalystActivity

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