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2025-08-11
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R-HSA-9948301
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ZNF598 K63 polyubiquitinates RPS10 (eS10) and RPS20 (uS10) of the 40S ribosomal subunit
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2025-08-09
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R-HSA-9954737
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RCHY1 K48 polyubiquitinates alanine-tailed nascent peptide
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2025-08-09
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R-HSA-9954727
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RCHY1 binds alanine-tailed nascent peptide and Ub:UBE2D2
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2025-08-09
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R-HSA-9948458
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NEMF polymerizes alanine residues onto the C-terminus of the nascent peptide ("CAT tailing")
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2025-08-09
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R-HSA-9948318
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LTN1 and TCF25 bind NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide-Ala
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2025-08-09
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R-HSA-9948300
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RQT complex:K63polyUb-80S ribosome dissociates yielding K63polyUb-40S subunit and 60S subunit:peptidyl-tRNA with nascent peptide
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2025-08-09
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R-HSA-9948291
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RQT complex binds K63polyUb-80S ribosome:no-go mRNA:peptidyl-tRNA with nascent peptide
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BibTex
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2025-08-09
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R-HSA-9948317
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ZNF598 and Ub:UBE2D1,2,3 bind stalled 80S ribosome
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2025-08-09
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R-HSA-9948415
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VCP hexamer and NPLOC4:UFD1 bind K48polyubiquitin of LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide
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BibTex
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2025-08-09
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R-HSA-9948362
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LTN1 K48 polyubiquitinates the nascent peptide in NEMF:60S ribosomal subunit:peptidyl-tRNA with nascent peptide
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BibTex
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2025-08-09
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R-SCE-9950045
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CDC48 hexamer, UFD1, and NPL4 bind K48polyubiquitin of RKR1:RQC2:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide
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2025-08-09
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R-HSA-9954723
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NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 binds alanine-tailed nascent peptide
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BibTex
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2025-08-09
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R-HSA-9954721
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NEDD8-K699-CUL2:ELOB:ELOC:RBX1:KLHDC10 K48 polyubiquitinates alanine-tailed nascent peptide
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BibTex
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2025-08-09
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R-HSA-9949632
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VCP hexamer extracts K48 polyubiquitinated alanine-tailed nascent peptide from VCP hexamer:UFD1:NPLOC4:LTN1:NEMF:TCF25:60S ribosome subunit:K48polyUb-nascent peptide
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BibTex
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2025-08-09
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R-HSA-9948427
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ANKZF1 cleaves the peptidyl-tRNA in VCP hexamer:LTN1:NEMF:60S ribosome subunit:peptidyl-tRNA with K48polyUb-nascent peptide
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2025-08-09
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R-SCE-9950051
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CDC48 extracts K48 polyubiquitinated Ala-Thr-tailed nascent peptide from CDC48 hexamer:UFD1:NPL4:RKR1:RQC2:RQC1:60S ribosome subunit:K48polyUb-nascent peptide-Ala-Thr
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BibTex
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2025-08-09
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R-HSA-9949676
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The proteasome degrades the alanine-tailed K48-polyUb nascent peptide bound to LTN1:NEMF:TCF25:VCP hexamer
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2025-08-09
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R-SCE-9953094
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The proteasome degrades the K48-polyUb nascent peptide-Ala-Thr bound to RKR1:RQC2:RQC1:CDC48 hexamer
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2025-08-09
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R-HSA-9948360
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NEMF binds 60S ribosomal subunit:peptidyl-tRNA with nascent peptide
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2025-08-09
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R-HSA-9954728
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The proteasome degrades the K48-polyubiquitinated alanine-tailed nascent peptide
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2025-08-09
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R-HSA-9954919
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ABCE1:ATP binds PELO:HBS1L-1:GTP:80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide and HBS1L-1:GDP is released
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2025-08-09
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R-HSA-9954730
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PELO:HBS1L-1:GTP binds 80S ribosome:non-stop mRNA:peptidyl-tRNA with nascent peptide
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BibTex
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2025-08-09
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R-HSA-9955731
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ABCE1:PELO:80S Ribosome:non-stop mRNA:peptidyl-tRNA with elongating peptide dissociates yielding ABCE1:40S ribosomal subunit, PELO, and 60S ribosomal subunit:peptidyl-tRNA with nascent peptide
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BibTex
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