Jie Liu

Department of Microbiology & Molecular Genetics, University of California, Davis
Reviewed Pathways (5/5)
Date Identifier Pathway Reference
2022-01-26 R-HSA-9701190 Defective homologous recombination repair (HRR) due to BRCA2 loss of function BibTex
2022-01-26 R-HSA-9709570 Impaired BRCA2 binding to RAD51 BibTex
2022-01-26 R-HSA-9709603 Impaired BRCA2 binding to PALB2 BibTex
2022-01-26 R-HSA-9763198 Impaired BRCA2 binding to SEM1 (DSS1) BibTex
2022-01-26 R-HSA-9709275 Impaired BRCA2 translocation to the nucleus BibTex
Reviewed Reactions (8/8)
Date Identifier Reaction Reference
2022-01-26 R-HSA-5693561 RAD51 binds BRCA2 at resected DNA DSBs BibTex
2022-01-26 R-HSA-9709273 BRCA2 translocates to the nucleus BibTex
2022-01-26 R-HSA-9763137 BRCA2 binds SEM1 (DSS1) BibTex
2022-01-26 R-HSA-5687640 POLQ extends annealed 3'-ssDNA overhangs in MMEJ BibTex
2022-01-26 R-HSA-9709571 BRCA2 mutants with BRC defects or a defect in the C-terminal RAD51 binding site do not bind RAD51 BibTex
2022-01-26 R-HSA-9709601 Defective recruitment of BRCA2 and RAD51 due to loss of BRCA2 function in PALB2 binding BibTex
2022-01-26 R-HSA-9763200 BRCA2 mutants do not bind SEM1 (DSS1) BibTex
2022-01-26 R-HSA-9709268 Defective BRCA2 does not translocate to the nucleus BibTex
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