FVa R534Q heavy chain [extracellular region]

Stable Identifier
R-HSA-9930427
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
F5 R534Q (29-737)
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
8164741 Mutation in blood coagulation factor V associated with resistance to activated protein C

Bertina, RM, Koeleman, BP, Koster, T, Rosendaal, FR, Dirven, RJ, de Ronde, H, van der Velden, PA, Reitsma, PH

Nature 1994
External Reference Information
External Reference
UniProt:P12259 F5
Gene Names
F5
Chain
signal peptide:1-28, chain:29-2224, chain:29-737, propeptide:738-1573, chain:1574-2224
Reference Genes
BioGPS Gene:2153 F5
COSMIC - genes:F5 F5
CTD Gene:2153 F5
dbSNP Gene:2153 F5
ENSEMBL:ENSG00000198734 F5
HGNC:3542 F5
KEGG:hsa:2153 F5
Monarch:2153 F5
NCBI Gene:2153 F5
OMIM:612309 F5
UCSC:P12259 F5
Reference Transcript
Other Identifiers
11723553_at
11723554_at
11751042_a_at
11758395_s_at
16696187
204713_PM_s_at
204713_s_at
204714_PM_s_at
204714_s_at
2153
231029_PM_at
231029_at
2443369
2443371
2443372
2443373
2443374
2443375
2443376
2443377
2443378
2443381
2443382
2443383
2443384
2443385
2443386
2443388
2443389
2443391
2443392
2443393
2443394
2443395
2443396
2443397
2443398
2443399
2443400
2443402
2443403
2443404
2443405
2443406
2443407
2443408
2443410
2443412
2443413
2443414
2443415
2443416
35245_at
62710_at
7922174
A_23_P148768
A_32_P41604
GE57848
GO:0003013
GO:0005507
GO:0005515
GO:0005576
GO:0005615
GO:0005788
GO:0005886
GO:0007596
GO:0007599
GO:0008015
GO:0016020
GO:0030134
GO:0031091
GO:0031093
GO:0031410
GO:0032571
GO:0033116
GO:0043226
GO:0046872
GO:1903561
HMNXSV003023557
Hs.165077.0.A1_3p_at
Hs.30054.0.S1_3p_a_at
ILMN_1709233
M16967_at
PH_hs_0002589
PH_hs_0020466
TC01003498.hg
g10518500_3p_a_at
Participates
as a member of
Other forms of this molecule
factor Va light chain [plasma membrane]
factor Va heavy chain [plasma membrane]
factor Va light chain [extracellular region]
factor Va heavy chain [extracellular region]
factor V [platelet alpha granule lumen]
factor V [extracellular region]
factor V activation peptide [extracellular region]
factor V (738-1046) [extracellular region]
factor Va (1047-2224) [extracellular region]
factor V (1047-1573) [extracellular region]
Factor V precursor [endoplasmic reticulum lumen]
p-Factor V precursor [endoplasmic reticulum lumen]
Factor V precursor [COPII-coated ER to Golgi transport vesicle]
Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
factor Va (1047-2224) [plasma membrane]
F5(29-534) [extracellular region]
F5(29-334) [extracellular region]
F5(335-534) [extracellular region]
F5(535-737) [extracellular region]
FVa A540V heavy chain [extracellular region]
FVa I387T (29-534) [extracellular region]
FVa R334T (29-534) [extracellular region]
Modified Residues
Name
L-arginine 534 replaced with L-glutamine
Coordinate
534
PsiMod
L-arginine removal [MOD:01632]
A protein modification that effectively removes or replaces an L-arginine.
L-glutamine residue [MOD:00016]
A protein modification that effectively converts a source amino acid residue to an L-glutamine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
ZINC - Substances
ZINC target
PRO
GlyGen
PDB
HPA
GeneCards
F5
Pharos - Targets
Orphanet
F5
ZINC - Predictions - Purchasable
HMDB Protein
Interactors (4)
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