Reactome | OLR1 [specific granule membrane]

OLR1 [specific granule membrane]

Stable Identifier

R-HSA-6799518

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

specific granule membrane

Synonyms

Oxidized low-density lipoprotein receptor 1, OLR1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P78380 OLR1

Gene Names

OLR1, CLEC8A, LOX1

Chain

chain:1-273, chain:-273

Reference Genes

BioGPS Gene:4973 OLR1

COSMIC (genes):OLR1 OLR1

CTD Gene:4973 OLR1

dbSNP Gene:4973 OLR1

ENSEMBL:ENSG00000173391 OLR1

ENSEMBL_homo_sapiens_GENE:ENSG00000173391.9 OLR1

HGNC:8133 OLR1

KEGG Gene (Homo sapiens):4973 OLR1

Monarch:4973 OLR1

NCBI Gene:4973 OLR1

OMIM:602601 OLR1

UCSC:P78380 OLR1

Reference Transcript

Other Identifiers

11722015_at

11722016_a_at

11722017_x_at

11750513_a_at

16761293

210004_PM_at

210004_at

3443978

3444044

3444045

3444046

3444047

3444048

3444050

3444051

3444052

3444053

3444055

37233_at

4973

7961142

A_24_P124624

D89050_at

GE79940

GO:0002376

GO:0003013

GO:0005041

GO:0005515

GO:0005576

GO:0005634

GO:0005654

GO:0005886

GO:0006508

GO:0006897

GO:0006954

GO:0007155

GO:0007159

GO:0008015

GO:0016020

GO:0016192

GO:0030246

GO:0031410

GO:0035579

GO:0038024

GO:0042157

GO:0042802

GO:0043226

GO:0043231

GO:0043235

GO:0045121

GO:0070821

HMNXSV003028525

ILMN_1723035

PH_hs_0030307

TC12001216.hg

g3941299_3p_at

Participates

as a member of

Specific granule membrane proteins [specific granule membrane] (Homo sapiens)

Other forms of this molecule

OLR1 [tertiary granule membrane]

OLR1 [plasma membrane]

Inferred To

Homologues of OLR1 [specific granule membrane] (Sus scrofa)

Olr1 [specific granule membrane] (Mus musculus)

Olr1 [specific granule membrane] (Rattus norvegicus)

OLR1 [specific granule membrane] (Bos taurus)

OLR1 [specific granule membrane] (Canis familiaris)

OLR1 [specific granule membrane] (Sus scrofa)

Cross References

RefSeq

NP_001166104.1, NP_002534.1, NP_001166103.1

OpenTargets

ENSG00000173391

HPA

ENSG00000173391-OLR1

GeneCards

P78380

Ensembl

ENST00000309539, ENST00000545927, ENSP00000439251, ENSP00000405116, ENST00000432556, ENSG00000173391, ENSP00000309124

PRO

P78380

Pharos - Targets

P78380

PDB

6TLA, 7W5D, 6TL9, 1YPU, 1YPO, 6TL7, 1YPQ, 1YXK, 7R8U, 1YXJ, 3VLG, 7XMP

Interactors (4)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P78380 OLR1	3	OLR1 [tertiary granule membrane] (R-HSA-6800883) OLR1 [plasma membrane] (R-HSA-203139) OLR1 [specific granule membrane] (R-HSA-6799518)	0.71	4
UniProt:P17987 TCP1	1	TCP1 [cytosol] (R-HSA-390448)	0.644	5
UniProt:P50991 CCT4	1	CCT4 [cytosol] (R-HSA-390458)	0.591	3
UniProt:P12259 F5	15	factor V [platelet alpha granule lumen] (R-HSA-141766) F5(535-737) [extracellular region] (R-HSA-5605103) F5(335-534) [extracellular region] (R-HSA-5605102) F5(29-334) [extracellular region] (R-HSA-5605101) F5(29-534) [extracellular region] (R-HSA-5605104) factor V activation peptide [extracellular region] (R-HSA-140787) factor V [extracellular region] (R-HSA-140697) factor Va heavy chain [extracellular region] (R-HSA-140691) factor Va light chain [extracellular region] (R-HSA-140690) factor Va heavy chain [plasma membrane] (R-HSA-140653) Factor V precursor [endoplasmic reticulum lumen] (R-HSA-5689447) p-Factor V precursor [endoplasmic reticulum lumen] (R-HSA-8956960) Factor V precursor [COPII-coated ER to Golgi transport vesicle] (R-HSA-5689792) Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689793) factor Va light chain [plasma membrane] (R-HSA-140660)	0.589	2

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