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F5(335-534) [extracellular region]
Stable Identifier
R-HSA-5605102
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Locations in the PathwayBrowser
Expand all
Hemostasis (Homo sapiens)
Formation of Fibrin Clot (Clotting Cascade) (Homo sapiens)
Common Pathway of Fibrin Clot Formation (Homo sapiens)
Activated protein C cleaves Factor Va intermediate form for Factor Va (Homo sapiens)
F5(335-534) [extracellular region] (Homo sapiens)
External Reference Information
External Reference
UniProt:P12259 F5
Gene Names
F5
Chain
signal peptide:1-28, chain:29-2224, chain:29-737, propeptide:738-1573, chain:1574-2224
Reference Genes
BioGPS Gene:2153 F5
COSMIC (genes):F5 F5
CTD Gene:2153 F5
dbSNP Gene:2153 F5
ENSEMBL:ENSG00000198734 F5
HGNC:3542 F5
KEGG:hsa:2153 F5
Monarch:2153 F5
NCBI Gene:2153 F5
OMIM:612309 F5
UCSC:P12259 F5
Reference Transcript
RefSeq:NM_000130.4 F5
Other Identifiers
11723553_at
11723554_at
11751042_a_at
11758395_s_at
16696187
204713_PM_s_at
204713_s_at
204714_PM_s_at
204714_s_at
2153
231029_PM_at
231029_at
2443369
2443371
2443372
2443373
2443374
2443375
2443376
2443377
2443378
2443381
2443382
2443383
2443384
2443385
2443386
2443388
2443389
2443391
2443392
2443393
2443394
2443395
2443396
2443397
2443398
2443399
2443400
2443402
2443403
2443404
2443405
2443406
2443407
2443408
2443410
2443412
2443413
2443414
2443415
2443416
35245_at
62710_at
7922174
A_23_P148768
A_32_P41604
GE57848
GO:0003013
GO:0005507
GO:0005515
GO:0005576
GO:0005615
GO:0005788
GO:0005886
GO:0007596
GO:0008015
GO:0016020
GO:0030134
GO:0031091
GO:0031093
GO:0031410
GO:0032571
GO:0033116
GO:0043226
GO:0046872
GO:1903561
HMNXSV003023557
Hs.165077.0.A1_3p_at
Hs.30054.0.S1_3p_a_at
ILMN_1709233
M16967_at
PH_hs_0002589
PH_hs_0020466
TC01003498.hg
g10518500_3p_a_at
Participates
as an output of
Activated protein C cleaves Factor Va intermediate form for Factor Va (Homo sapiens)
Other forms of this molecule
Factor V precursor [endoplasmic reticulum lumen]
p-Factor V precursor [endoplasmic reticulum lumen]
factor Va light chain [plasma membrane]
factor Va heavy chain [plasma membrane]
factor Va light chain [extracellular region]
factor Va heavy chain [extracellular region]
factor V [extracellular region]
factor V activation peptide [extracellular region]
Factor V precursor [COPII-coated ER to Golgi transport vesicle]
Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane]
F5(29-534) [extracellular region]
F5(29-334) [extracellular region]
F5(535-737) [extracellular region]
factor V [platelet alpha granule lumen]
Inferred To
f5 [extracellular region]
(Danio rerio)
F5 [extracellular region]
(Bos taurus)
F5 [extracellular region]
(Canis familiaris)
F5 [extracellular region]
(Sus scrofa)
F5(335-534) [extracellular region]
(Gallus gallus)
F5(335-534) [extracellular region]
(Mus musculus)
Cross References
RefSeq
NP_000121.2
Guide to Pharmacology - Targets
2606
OpenTargets
ENSG00000198734
ENSEMBL
ENSP00000356771
,
ENST00000367797
ZINC - Substances
FA5_HUMAN
ZINC target
P12259
PRO
P12259
GlyGen
P12259
PDB
7TPQ
,
7TPP
,
3P70
,
7KXY
,
1CZT
,
7KVF
,
1CZS
,
1CZV
,
8TN9
,
8FDG
,
3P6Z
,
3S9C
,
7KVE
HPA
ENSG00000198734-F5
Pharos - Targets
P12259
Orphanet
F5
ZINC - Predictions - Purchasable
FA5_HUMAN
HMDB Protein
HMDBP02118
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78380 OLR1
3
OLR1 [tertiary granule membrane]
(R-HSA-6800883)
OLR1 [plasma membrane]
(R-HSA-203139)
OLR1 [specific granule membrane]
(R-HSA-6799518)
0.589
2
UniProt:A4D1S0 KLRG2
0.527
2
UniProt:Q13201 MMRN1
2
MMRN1(20-1228) [extracellular region]
(R-HSA-114635)
MMRN1(20-1228) [platelet alpha granule lumen]
(R-HSA-114634)
0.527
2
UniProt:P32971 TNFSF8
1
TNFSF8 [plasma membrane]
(R-HSA-5667148)
0.527
3
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