Reactome | FucT-MMRN1(20-1228) [endoplasmic reticulum lumen]

FucT-MMRN1(20-1228) [endoplasmic reticulum lumen]

Stable Identifier

R-HSA-9935466

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum lumen

Synonyms

fucosyl-Multimerin 1

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q13201 MMRN1

Gene Names

MMRN1, ECM, EMILIN4, GPIA*, MMRN

Chain

signal peptide:1-19, chain:20-1228, chain:184-1228, chain:318-1228

Reference Genes

BioGPS Gene:22915 MMRN1

COSMIC (genes):MMRN1 MMRN1

CTD Gene:22915 MMRN1

dbSNP Gene:22915 MMRN1

ENSEMBL:ENSG00000138722 MMRN1

HGNC:7178 MMRN1

KEGG:hsa:22915 MMRN1

Monarch:22915 MMRN1

NCBI Gene:22915 MMRN1

OMIM:601456 MMRN1

UCSC:Q13201 MMRN1

Reference Transcript

Other Identifiers

11722924_a_at

11722925_x_at

11722926_a_at

11748235_a_at

16968878

205612_PM_at

205612_at

22915

2735758

2735760

2735763

2735764

2735765

2735766

2735767

2735768

2735769

2735770

2735775

2735776

2735777

2735780

2735782

2735784

2735785

2735786

2735787

2735788

2735789

2735790

2735791

35664_at

8096415

A_14_P133921

A_23_P18539

A_33_P3212257

GE81743

GE87898

GO:0005198

GO:0005201

GO:0005509

GO:0005515

GO:0005576

GO:0007155

GO:0007596

GO:0030312

GO:0030948

GO:0031012

GO:0031091

GO:0031093

GO:0033627

GO:0061045

GO:0090051

GO:1901731

GO:1990972

HMNXSV003023625

ILMN_1660114

PH_hs_0013724

TC04000493.hg

U27109_at

g6681258_3p_at

Participates

as a member of

Fuc-EMI proteins [endoplasmic reticulum lumen] (Homo sapiens)

Other forms of this molecule

MMRN1(20-1228) [endoplasmic reticulum lumen]

FucT-MMRN1(20-1228) [extracellular region]

FucT-MMRN1(20-1228) [platelet alpha granule lumen]

Inferred To

Mmrn1 [endoplasmic reticulum lumen] (Mus musculus)

Mmrn1 [endoplasmic reticulum lumen] (Rattus norvegicus)

emilin1a [endoplasmic reticulum lumen] (Danio rerio)

MMRN1 [endoplasmic reticulum lumen] (Bos taurus)

MMRN1 [endoplasmic reticulum lumen] (Gallus gallus)

MMRN1 [endoplasmic reticulum lumen] (Sus scrofa)

mmrn1 [endoplasmic reticulum lumen] (Xenopus tropicalis)

Modified Residues

Name

O-fucosyl-L-threonine at 216

Coordinate

216

PsiMod Name

O-fucosyl-L-threonine

PsiMod Definition

A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.

Name

O-fucosyl-L-threonine at 265

Coordinate

265

PsiMod Name

O-fucosyl-L-threonine

PsiMod Definition

A protein modification that effectively converts an threonine residue to an O-fucosylthreonine.

Cross References

RefSeq

XP_016863382.1, NP_031377.2, NP_001358332.1

ENSEMBL

ENST00000394980, ENSP00000378431, ENSP00000264790, ENST00000264790, ENSG00000138722

OpenTargets

ENSG00000138722

GeneCards

MMRN1

HPA

ENSG00000138722-MMRN1

PRO

Q13201

Pharos - Targets

Q13201

GlyGen

Q13201

Interactors (3)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P12259 F5	15	factor Va light chain [plasma membrane] (R-HSA-140660) factor Va heavy chain [plasma membrane] (R-HSA-140653) factor Va light chain [extracellular region] (R-HSA-140690) factor Va heavy chain [extracellular region] (R-HSA-140691) factor V [platelet alpha granule lumen] (R-HSA-141766) factor V [extracellular region] (R-HSA-140697) factor V activation peptide [extracellular region] (R-HSA-140787) Factor V precursor [endoplasmic reticulum lumen] (R-HSA-5689447) p-Factor V precursor [endoplasmic reticulum lumen] (R-HSA-8956960) Factor V precursor [COPII-coated ER to Golgi transport vesicle] (R-HSA-5689792) Factor V precursor [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5689793) F5(29-534) [extracellular region] (R-HSA-5605104) F5(29-334) [extracellular region] (R-HSA-5605101) F5(335-534) [extracellular region] (R-HSA-5605102) F5(535-737) [extracellular region] (R-HSA-5605103)	0.527	2
UniProt:P02649 APOE	10	APOE [extracellular region] (R-HSA-174646) APOE [endoplasmic reticulum lumen] (R-HSA-6784908) p-APOE [endoplasmic reticulum lumen] (R-HSA-8956980) APOE [endocytic vesicle lumen] (R-HSA-3221641) APOE-4 [extracellular region] (R-HSA-9711070) APOE [plasma membrane] (R-HSA-174615) APOE [clathrin-coated endocytic vesicle membrane] (R-HSA-174651) APOE [endosome membrane] (R-HSA-174766) APOE [endosome lumen] (R-HSA-174804) APOE [early endosome] (R-HSA-2429687)	0.527	2
UniProt:Q15517 CDSN	2	CDSN [cornified envelope] (R-HSA-8847707) CDSN [plasma membrane] (R-HSA-6814395)	0.527	2

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