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PABPN1 [cytosol]
Stable Identifier
R-HSA-9822424
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
fullName evidence="22"Polyadenylate-binding protein 2, PABP2_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Z-decay: degradation of maternal mRNAs by zygotically expressed factors (Homo sapiens)
DIS3L2 binds PABPN1 in PABPN1:uridylated mRNA complex (Homo sapiens)
DIS3L2:PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
DIS3L2 hydrolyzes uridylated mRNA (Homo sapiens)
DIS3L2:PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
PABPN1 binds oligouridylated mRNA (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
PABPN1 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q86U42 PABPN1
Gene Names
PABPN1, PAB2, PABP2
Chain
initiator methionine:, chain:2-306
Reference Genes
BioGPS Gene:8106 PABPN1
COSMIC (genes):PABPN1 PABPN1
CTD Gene:8106 PABPN1
dbSNP Gene:8106 PABPN1
ENSEMBL:ENSG00000100836 PABPN1
ENSEMBL_homo_sapiens_GENE:ENSG00000100836.11 PABPN1
HGNC:8565 PABPN1
KEGG Gene (Homo sapiens):8106 PABPN1
Monarch:8106 PABPN1
NCBI Gene:8106 PABPN1
OMIM:602279 PABPN1
UCSC:Q86U42 PABPN1
Reference Transcript
RefSeq:NM_004643.3 PABPN1
Other Identifiers
11718844_s_at
11718845_a_at
11763165_at
201544_3p_x_at
201544_PM_x_at
201544_x_at
201545_PM_s_at
201545_s_at
213046_PM_at
213046_at
3529085
3529088
3529090
3529092
3529094
3529096
3529097
3529098
3529099
3529100
3529101
3529102
3529103
3840483
39050_at
7973384
8106
A_14_P111774
A_23_P128828
GE79123
GO:0000165
GO:0003012
GO:0003676
GO:0003723
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006396
GO:0006397
GO:0006913
GO:0006936
GO:0008143
GO:0016071
GO:0016607
GO:0016973
GO:0023052
GO:0042405
GO:0043226
GO:0070063
GO:0071222
GO:1904247
GO:1990904
HMNXSV003039577
Hs.117176.0.S1_3p_a_at
Hs.117176.0.S1_3p_x_at
Hs.117176.1.S1_3p_at
ILMN_1759154
PH_hs_0006427
TC14002292.hg
g4758875_3p_a_at
Participates
as an input of
PABPN1 binds oligouridylated mRNA (Homo sapiens)
as an output of
DIS3L2 hydrolyzes uridylated mRNA (Homo sapiens)
as a component of
PABPN1:uridylated partially deadenylated mRNA complex [cytosol] (Homo sapiens)
Other forms of this molecule
PABPN1 [nucleoplasm]
Cross References
RefSeq
NP_004634.1
OpenTargets
ENSG00000100836
GeneCards
Q86U42
HPA
ENSG00000100836-PABPN1
Ensembl
ENSG00000100836
,
ENSP00000216727
,
ENSP00000380446
,
ENST00000216727
,
ENST00000397276
PRO
Q86U42
Pharos - Targets
Q86U42
Orphanet
16602
PDB
3B4M
,
3UCG
,
3B4D
HMDB Protein
HMDBP08498
Interactors (7)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.696
5
UniProt:P67809 YBX1
5
p-S32,S36-YBX1 [nucleoplasm]
(R-HSA-9733227)
p-S32,S36-YBX1 [cytosol]
(R-HSA-9736837)
YBX1 [cytosol]
(R-HSA-9736840)
YBX1 [nucleoplasm]
(R-HSA-72041)
YBX1 [extracellular region]
(R-HSA-9017791)
0.558
4
UniProt:Q53F19 NCBP3
0.527
5
UniProt:Q08211 DHX9
3
DHX9 [nucleoplasm]
(R-HSA-53517)
DHX9 [cytosol]
(R-HSA-847700)
p-DHX9 [cytosol]
(R-HSA-9836168)
0.527
2
UniProt:Q09161 NCBP1
2
NCBP1 [nucleoplasm]
(R-HSA-51469)
NCBP1 [cytosol]
(R-HSA-162459)
0.527
6
UniProt:P11940 PABPC1
1
PABPC1 [cytosol]
(R-HSA-156803)
0.499
2
UniProt:Q9NR30 DDX21
1
DDX21 [nucleoplasm]
(R-HSA-5250652)
0.483
2
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