Reactome | ZDHHC5 [Golgi membrane]

ZDHHC5 [Golgi membrane]

Stable Identifier

R-HSA-9766353

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

Golgi membrane

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        Late SARS-CoV-2 Infection Events (Homo sapiens)
        
        Translation of Structural Proteins (Homo sapiens)
        
        Maturation of spike protein (Homo sapiens)
        
        Spike protein gets palmitoylated (Homo sapiens)
        
        Palmitoyltransferases [Golgi membrane] (Homo sapiens)
        
        ZDHHC5:GOLGA7 [Golgi membrane] (Homo sapiens)
        
        ZDHHC5 [Golgi membrane] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q9C0B5 ZDHHC5

Gene Names

ZDHHC5, KIAA1748, ZNF375

Chain

chain:1-715

Reference Genes

BioGPS Gene:25921 ZDHHC5

COSMIC (genes):ZDHHC5 ZDHHC5

CTD Gene:25921 ZDHHC5

dbSNP Gene:25921 ZDHHC5

ENSEMBL:ENSG00000156599.11 ZDHHC5

HGNC:18472 ZDHHC5

KEGG Gene (Homo sapiens):25921 ZDHHC5

Monarch:25921 ZDHHC5

NCBI Gene:25921 ZDHHC5

OMIM:614586 ZDHHC5

UCSC:Q9C0B5 ZDHHC5

Reference Transcript

Other Identifiers

11744947_a_at

11755656_a_at

16724901

224858_PM_at

224858_at

224868_PM_at

224868_at

25921

3331432

3331434

3331435

3331441

3331442

3331449

3331450

3331452

3331453

3331454

3331456

3331457

3331458

3331461

3331462

3331463

3331464

3331465

3331466

3331467

3331468

3331469

3331470

3331471

3331472

3331474

65616_at

7940051

A_14_P200292

A_23_P98532

GE536414

GE56533

GO:0000139

GO:0002376

GO:0003824

GO:0005515

GO:0005794

GO:0005886

GO:0006869

GO:0016020

GO:0016409

GO:0016740

GO:0016746

GO:0018345

GO:0019706

GO:0023052

GO:0030425

GO:0031410

GO:0036211

GO:0043226

GO:0045087

GO:0045202

GO:0045335

GO:0062208

GO:0072659

GO:0098542

GO:0098978

GO:0098982

GO:0099072

GO:0099091

GO:0140096

GO:1903078

GO:1905171

HMNXSV003008745

Hs.27239.0.S1_3p_at

Hs.27239.0.S2_3p_at

ILMN_1679358

PH_hs_0002413

TC11000471.hg

TC11002680.hg

Participates

as a component of

ZDHHC5:GOLGA7 [Golgi membrane] (Homo sapiens)

Cross References

RefSeq

XP_011543202.1, XP_011543203.1, XP_011543201.1, NP_056272.2

OpenTargets

ENSG00000156599

HPA

ENSG00000156599-ZDHHC5

GeneCards

Q9C0B5

Ensembl

ENSG00000156599, ENSP00000432202, ENSP00000287169, ENST00000527985, ENST00000287169

PRO

Q9C0B5

Pharos - Targets

Q9C0B5

HMDB Protein

HMDBP12029

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P0DTC2 S	20	S(686-815) [plasma membrane] (R-COV-9770188) Spike S2' Fragment [plasma membrane] (R-COV-9770189) S1 [plasma membrane] (R-COV-9769950) fully glycosylated Spike [plasma membrane] (R-COV-9733472) nascent Spike [endoplasmic reticulum lumen] (R-COV-9694796) 14-sugar N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9694459) Man(9) N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696892) high-mannose N-glycan unfolded Spike [endoplasmic reticulum lumen] (R-COV-9696875) high-mannose N-glycan folded Spike [endoplasmic reticulum lumen] (R-COV-9696880) high-mannose N-glycan folded Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9766369) high-mannose N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696943) di-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696920) tri-antennary N-glycan-PALM-Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9697006) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment] (R-COV-9696997) complex N-glycan-PALM-Spike S2 Fragment [plasma membrane] (R-COV-9769952) fully glycosylated Spike [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-COV-9698330) fully glycosylated Spike [virion membrane] (R-COV-9698327) complex N-glycan-PALM-Spike S1 Fragment [endocytic vesicle membrane] (R-COV-9694745) complex N-glycan-PALM-Spike S2 Fragment [endocytic vesicle membrane] (R-COV-9694343) complex N-glycan-PALM-Spike S2 Fragment [virion membrane] (R-COV-9694791)	0.725	5

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