Reactome | CHMP7 [cytosol]

CHMP7 [cytosol]

Stable Identifier

R-HSA-917703

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Charged multivesicular body protein 7, CHMP7_HUMAN

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Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q8WUX9 CHMP7

Gene Names

CHMP7

Chain

chain:1-453

Reference Genes

BioGPS Gene:91782 CHMP7

COSMIC (genes):CHMP7 CHMP7

CTD Gene:91782 CHMP7

dbSNP Gene:91782 CHMP7

ENSEMBL:ENSG00000147457 CHMP7

ENSEMBL_homo_sapiens_GENE:ENSG00000147457.14 CHMP7

HGNC:28439 CHMP7

KEGG Gene (Homo sapiens):91782 CHMP7

Monarch:91782 CHMP7

NCBI Gene:91782 CHMP7

OMIM:611130 CHMP7

UCSC:Q8WUX9 CHMP7

Reference Transcript

RefSeq:NM_152272.4 CHMP7

Other Identifiers

11716147_s_at

11750037_a_at

17066845

212313_PM_at

212313_at

3089854

3089855

3089856

3089857

3089858

3089860

3089864

3089866

3089870

3089871

3089873

3089874

3089875

3089876

3089878

3089881

3089882

3089883

3089884

3089885

3089886

34871_at

8145259

91782

A_23_P303203

A_32_P70220

GE87421

GO:0000278

GO:0000421

GO:0000776

GO:0000785

GO:0000815

GO:0000910

GO:0001778

GO:0005515

GO:0005634

GO:0005635

GO:0005643

GO:0005654

GO:0005694

GO:0005737

GO:0005764

GO:0005765

GO:0005768

GO:0005771

GO:0005773

GO:0005828

GO:0005829

GO:0005856

GO:0005886

GO:0006900

GO:0006914

GO:0006997

GO:0007010

GO:0007034

GO:0007040

GO:0007059

GO:0007080

GO:0009898

GO:0010458

GO:0015031

GO:0016192

GO:0030163

GO:0030496

GO:0031410

GO:0031468

GO:0032511

GO:0032585

GO:0036258

GO:0039702

GO:0042060

GO:0043162

GO:0043226

GO:0045324

GO:0046761

GO:0051469

GO:0061024

GO:0061763

GO:0061952

GO:0071168

GO:0071985

GO:0090148

GO:0097352

GO:0140014

GO:1901673

GO:1902774

GO:1904903

GO:1904930

HMNXSV003031815

Hs.5019.0.S1_3p_at

ILMN_1795933

PH_hs_0000516

TC08000184.hg

Participates

as an output of

as an input of

CHMP7 binds LEMD2 (Homo sapiens)

as a component of

Other forms of this molecule

CHMP7 [endosome membrane]

Inferred To

CHMP7 [cytosol] (Bos taurus)

CHMP7 [cytosol] (Canis familiaris)

CHMP7 [cytosol] (Gallus gallus)

CHMP7 [cytosol] (Saccharomyces cerevisiae)

CHMP7 [cytosol] (Sus scrofa)

Homologues of CHMP7 [cytosol] (Dictyostelium discoideum)

Homologues of CHMP7 [cytosol] (Saccharomyces cerevisiae)

Ghost homologue of CHMP7 [cytosol] (Caenorhabditis elegans)

chmp6 [cytosol] (Dictyostelium discoideum)

vps20 [cytosol] (Schizosaccharomyces pombe)

BcDNA.GH08385 [cytosol] (Drosophila melanogaster)

chmp7 [cytosol] (Danio rerio)

chmp7 [cytosol] (Dictyostelium discoideum)

chmp7 [cytosol] (Xenopus tropicalis)

Chmp7 [cytosol] (Mus musculus)

Chmp7 [cytosol] (Rattus norvegicus)

VPS20 [cytosol] (Saccharomyces cerevisiae)

Cross References

RefSeq

NP_689485.1

OpenTargets

ENSG00000147457

HPA

ENSG00000147457-CHMP7

GeneCards

Q8WUX9

Ensembl

ENSP00000324491, ENSG00000147457, ENST00000397677, ENST00000519503, ENSP00000427948, ENSP00000380794, ENST00000313219

PRO

Q8WUX9

Pharos - Targets

Q8WUX9

Interactors (21)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P01112 HRAS	20	HRAS Q61R [plasma membrane] (R-HSA-6802458) HRAS Q61L [plasma membrane] (R-HSA-6802452) HRAS Q61K [plasma membrane] (R-HSA-6802442) HRAS G13R [plasma membrane] (R-HSA-6802368) HRAS G12V [plasma membrane] (R-HSA-6802350) HRAS G12S [plasma membrane] (R-HSA-6802343) HRAS T58I [plasma membrane] (R-HSA-9656014) HRAS G13C [plasma membrane] (R-HSA-9656008) HRAS K117R [plasma membrane] (R-HSA-9656010) HRAS G13V [plasma membrane] (R-HSA-9656579) HRAS G13D [plasma membrane] (R-HSA-9656572) HRAS G13S [plasma membrane] (R-HSA-9656574) HRAS K117N [plasma membrane] (R-HSA-9656603) HRAS G12D [plasma membrane] (R-HSA-9656564) HRAS G12C [plasma membrane] (R-HSA-9656561) S-Farn-Me HRAS [plasma membrane] (R-HSA-9665052) HRAS [plasma membrane] (R-HSA-62717) S-Farn-Me PalmS HRAS [Golgi membrane] (R-HSA-9647896) S-Farn-Me HRAS [endoplasmic reticulum membrane] (R-HSA-9647796) S-Farn-HRAS [endoplasmic reticulum membrane] (R-HSA-9647788)	0.659	4
UniProt:Q9UMX0 UBQLN1	1	UBQLN1 [cytosol] (R-HSA-8866006)	0.556	3
UniProt:P22607 FGFR3	20	FGFR3(23-760)-TACC3(612-838) fusion [plasma membrane] (R-HSA-8853144) FGFR3(23-760)-BAIAP2L1(18-522) fusion [plasma membrane] (R-HSA-8853131) FGFR3(23-793)-TACC3(143-838) fusion [plasma membrane] (R-HSA-8853152) FGFR3(23-758)-TACC3(549-838) fusion [plasma membrane] (R-HSA-8853124) FGFR3(23-758)-TACC3(649-838) fusion [plasma membrane] (R-HSA-8853125) FGFR3(23-760)-TACC3(647-838) fusion [plasma membrane] (R-HSA-8853127) FGFR3 K650T [plasma membrane] (R-HSA-1614411) FGFR3 K650N [plasma membrane] (R-HSA-1614406) FGFR3 K650M [plasma membrane] (R-HSA-1614402) FGFR3 K650Q [plasma membrane] (R-HSA-1614410) FGFR3 A391E [plasma membrane] (R-HSA-1614390) FGFR3 K650E [plasma membrane] (R-HSA-1614400) FGFR3 G380R [plasma membrane] (R-HSA-1614398) FGFR3 G382D [plasma membrane] (R-HSA-2018740) FGFR3 805fs*141 [plasma membrane] (R-HSA-1614387) FGFR3 [plasma membrane] (R-HSA-2038357) FGFR3 S371C [plasma membrane] (R-HSA-1614421) FGFR3 Y373C [plasma membrane] (R-HSA-1614424) FGFR3 G370C [plasma membrane] (R-HSA-1614394) FGFR3 R248C [plasma membrane] (R-HSA-1614419)	0.556	3
UniProt:P06307 CCK	1	CCK [extracellular region] (R-HSA-388539)	0.556	3
UniProt:P54652 HSPA2	2	HSPA2 [cytosol] (R-HSA-3371408) HSPA2 [nucleoplasm] (R-HSA-912480)	0.556	3
UniProt:Q0VDC6 Q0VDC6			0.556	3
IntAct:EBI-25847655 CCSB			0.556	3
UniProt:P13473-2 P134732			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:O14645 IDLC			0.556	3
UniProt:P55212 CASP6	5	CASP6 (1-293) [cytosol] (R-HSA-6798132) CASP6(194-293) [nucleoplasm] (R-HSA-352246) CASP6(24-179) [nucleoplasm] (R-HSA-352247) CASP6(24-179) [cytosol] (R-HSA-350313) CASP6(194-293) [cytosol] (R-HSA-266128)	0.556	3
UniProt:P62826 RAN	2	RAN [nucleoplasm] (R-HSA-165528) RAN [cytosol] (R-HSA-165540)	0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:P28329-3 P283293			0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:G5E9A7 G5E9A7			0.556	3
UniProt:A0A6Q8PF08 A0A6Q8PF08			0.556	3
UniProt:Q7Z699 SPRED1	2	SPRED1 [plasma membrane] (R-HSA-5658225) SPRED1 [cytosol] (R-HSA-5654207)	0.556	3
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q15102 PAFAH1B3	1	PAFAH1B3 [cytosol] (R-HSA-8848134)	0.553	2
UniProt:Q9H444 CHMP4B	2	CHMP4B [cytosol] (R-HSA-917708) CHMP4B [endosome membrane] (R-HSA-9631202)	0.543	3

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