CHMP7 binds LEMD2

Stable Identifier
R-HSA-9668335
Type
Reaction [binding]
Species
Homo sapiens
Compartment
cytosol, nuclear envelope
ReviewStatus
5/5
Locations in the PathwayBrowser
Expand all
General
SVG | 
PNG
Low
Medium
High
 | PPTX  | SBGN
CHMP7 binds LEMD2
Click the image above or here to open this reaction in the Pathway Browser
The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The ESCRT-III subunit CHMP7 binds LEMD2 (LEM2) at holes in the reforming nuclear envelope that are juxtaposed to the chromatin surface (Vietri et al 2015, Gu et al 2017).
Literature References
PubMed ID Title Journal Year
28242692 LEM2 recruits CHMP7 for ESCRT-mediated nuclear envelope closure in fission yeast and human cells

Frost, A, Gu, M, Redd, MJ, Ullman, KS, Ladinsky, MS, Sundquist, WI, Chen, OS, Bjorkman, PJ, Nikolova, L, LaJoie, D, von Appen, A

Proc. Natl. Acad. Sci. U.S.A. 2017
Participants
Input
Output
Participates
as an event of
Orthologous Events
CHMP7 binds LEMD2 (Dictyostelium discoideum)
CHMP7 binds LEMD2 (Saccharomyces cerevisiae)
CHMP7 binds LEMD2 (Schizosaccharomyces pombe)
Authored
Gerace, L  (2019-11-07)
Created
Orlic-Milacic, M  (2019-11-25)
Cite Us!