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GRIN2C [plasma membrane]
Stable Identifier
R-HSA-419560
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glutamate (NMDA) receptor subunit epsilon-3, NR2C
Locations in the PathwayBrowser
Expand all
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Neurexins and neuroligins (Homo sapiens)
BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:PSD-95:BEGAIN [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 binds SPAR (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR binds PDLIM5 (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR:PDLIM5 [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDAR binds PSD-95 subfamily members (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
PSD-95 binds NMDA receptor (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
SALM1 binds NMDA receptor (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
SALM1:NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
SALM2 associate with AMPA and NMDA receptors (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
SALM2:AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Assembly and cell surface presentation of NMDA receptors (Homo sapiens)
CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GluN1 (GRIN1) binds to ACTN2 at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GluN1 (GRIN1) binds to NEFL at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors bind to postsynaptic density proteins (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Negative regulation of NMDA receptor-mediated neuronal transmission (Homo sapiens)
CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:LRRC7:CaMKII dodecamer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Long-term potentiation (Homo sapiens)
SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Ca2+ influx into the post-synaptic cell (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Mg2+ binds GRIN1:GRIN2 NMDA receptors (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2C [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q14957 GRIN2C
Gene Names
GRIN2C, NMDAR2C
Chain
signal peptide:1-19, chain:20-1233
Reference Genes
BioGPS Gene:2905 GRIN2C
COSMIC (genes):GRIN2C GRIN2C
CTD Gene:2905 GRIN2C
dbSNP Gene:2905 GRIN2C
ENSEMBL:ENSG00000161509 GRIN2C
ENSEMBL_homo_sapiens_GENE:ENSG00000161509.14 GRIN2C
HGNC:4587 GRIN2C
KEGG Gene (Homo sapiens):2905 GRIN2C
Monarch:2905 GRIN2C
NCBI Gene:2905 GRIN2C
OMIM:138254 GRIN2C
UCSC:Q14957 GRIN2C
Reference Transcript
RefSeq:NM_000835.4 GRIN2C
Other Identifiers
11740655_at
16848640
210400_PM_at
210400_at
2905
3770423
3770424
3770425
3770426
3770427
3770428
3770429
3770432
3770433
3770435
3770437
3770438
3770440
3770441
3770442
3770443
3770444
3770445
3770448
3770453
41539_at
8018220
A_23_P49546
A_24_P25530
GE59418
GO:0004970
GO:0004972
GO:0005215
GO:0005216
GO:0005261
GO:0005515
GO:0005783
GO:0005789
GO:0005886
GO:0006811
GO:0007215
GO:0007420
GO:0009611
GO:0015276
GO:0016020
GO:0017146
GO:0019722
GO:0022849
GO:0022890
GO:0023052
GO:0030163
GO:0031090
GO:0033058
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0042177
GO:0042391
GO:0043226
GO:0045202
GO:0045211
GO:0048167
GO:0048168
GO:0048856
GO:0050877
GO:0050885
GO:0051968
GO:0055085
GO:0060079
GO:0060089
GO:0060291
GO:0097060
GO:0097553
GO:0098655
GO:0098839
GO:0098976
GO:0098978
GO:1903539
GO:1904062
GO:1904315
GO:2000463
HMNXSV003015376
HMNXSV003042745
ILMN_2227790
L76224_at
PH_hs_0025556
TC17001863.hg
g1196448_3p_at
Participates
as a member of
NR2 subunits [plasma membrane] (Homo sapiens)
as a component of
GRIN1:GRIN2C di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y-GRIN2C [plasma membrane]
GRIN2C [endoplasmic reticulum membrane]
Inferred To
Nmdar2 [plasma membrane]
(Drosophila melanogaster)
GRIN2C [plasma membrane]
(Canis familiaris)
GRIN2C [plasma membrane]
(Gallus gallus)
GRIN2C [plasma membrane]
(Mus musculus)
GRIN2C [plasma membrane]
(Rattus norvegicus)
GRIN2C [plasma membrane]
(Sus scrofa)
nmr-2 [plasma membrane]
(Caenorhabditis elegans)
Cross References
RefSeq
NP_000826.2
Guide to Pharmacology - Targets
458
OpenTargets
ENSG00000161509
HPA
ENSG00000161509-GRIN2C
GeneCards
Q14957
ZINC target
Q14957
Ensembl
ENST00000293190
,
ENSP00000293190
,
ENSG00000161509
PRO
Q14957
Pharos - Targets
Q14957
ZINC - Predictions - Purchasable
NMDE3_HUMAN
HMDB Protein
HMDBP01643
PDB
8E92
,
8E97
,
8E98
,
8E93
,
8E99
,
8E94
Interactors (113)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P31016 Dlg4
3
Dlg4 [endocytic vesicle membrane]
(R-RNO-416847)
Dlg4 [cytosol]
(R-RNO-6794248)
Dlg4 [plasma membrane]
(R-RNO-9612601)
0.558
2
UniProt:Q62936
2
Dlg3 [cytosol]
(R-RNO-6794232)
Dlg3 [plasma membrane]
(R-RNO-443609)
0.558
6
UniProt:P78352 DLG4
3
DLG4 [cytosol]
(R-HSA-6794267)
DLG4 [endocytic vesicle membrane]
(R-HSA-416847)
DLG4 [plasma membrane]
(R-HSA-202135)
0.558
4
UniProt:P41271-2 NBL1
0.556
3
UniProt:Q5T0J7-2 TEX35
0.556
3
UniProt:P62701 RPS4X
2
RPS4X [nucleoplasm]
(R-HSA-6798713)
RPS4X [cytosol]
(R-HSA-72375)
0.556
3
UniProt:Q96LL4 CH048
0.556
3
UniProt:Q9H0X6 RN208
0.556
3
UniProt:Q9UPQ4-2 Q9UPQ42
0.556
3
UniProt:Q8WUX9 CHMP7
2
CHMP7 [cytosol]
(R-HSA-917703)
CHMP7 [endosome membrane]
(R-HSA-9631168)
0.556
3
UniProt:Q8WTV1 THAP3
0.556
3
UniProt:B7Z3E8 B7Z3E8
0.556
3
IntAct:EBI-25836264 CCSB
0.556
3
UniProt:Q5BJF6-2 ODF2
0.556
3
UniProt:O15273 TCAP
1
TCAP [cytosol]
(R-HSA-390571)
0.556
3
UniProt:Q8NDH6-2 ICA1L
0.556
3
UniProt:P02458-1 COL2A1
0.556
3
UniProt:P24941 CDK2
5
p-Y15-CDK2 [nucleoplasm]
(R-HSA-187905)
p-CDK2 [nucleoplasm]
(R-HSA-68370)
CDK2 [cytosol]
(R-HSA-157440)
CDK2 [nucleoplasm]
(R-HSA-68365)
p-T160-CDK2 [nucleoplasm]
(R-HSA-187967)
0.556
3
UniProt:Q9H2C1 LHX5
0.556
3
UniProt:Q68G74 LHX8
0.556
3
UniProt:Q96CS2 HAUS1
1
HAUS1 [cytosol]
(R-HSA-8855199)
0.556
3
UniProt:Q658K8 EF1DL
0.556
3
UniProt:O60902-3 SHOX2
0.556
3
UniProt:O60237-2 PPP1R12B
0.556
3
UniProt:Q9NTN9-3 SEMA4G
0.556
3
UniProt:Q9Y3D0 CIAO2B
1
FAM96B [cytosol]
(R-HSA-2161124)
0.556
3
UniProt:Q1L5Z9 LONF2
0.556
3
UniProt:O43741 PRKAB2
2
PRKAB2 [cytosol]
(R-HSA-200413)
PRKAB2 [nucleoplasm]
(R-HSA-164096)
0.556
3
UniProt:Q6PHZ7 Q6PHZ7
0.556
3
UniProt:Q6UY14-3 ADAMTSL4
0.556
3
UniProt:P49459 UBE2A
3
UBE2A [cytosol]
(R-HSA-947617)
Ub-C88-UBE2A [nucleoplasm]
(R-HSA-8864186)
UBE2A [nucleoplasm]
(R-HSA-8852048)
0.556
3
UniProt:O15534 PER1
4
p-S-PER1 [cytosol]
(R-HSA-400310)
p-S-PER1 [nucleoplasm]
(R-HSA-3325590)
PER1 [cytosol]
(R-HSA-400373)
Ub-p-S-PER1 [cytosol]
(R-HSA-517831)
0.556
3
UniProt:Q49A26-4 GLYR1
0.556
3
UniProt:Q6IN84-2 MRM1
0.556
3
UniProt:Q14117 DPYS
1
DPYS [cytosol]
(R-HSA-73467)
0.556
3
UniProt:Q15382 RHEB
2
RHEB [endosome membrane]
(R-HSA-5656350)
RHEB [lysosomal membrane]
(R-HSA-165190)
0.556
3
UniProt:Q14847-2 LASP1
0.556
3
UniProt:Q5PSV4 BRM1L
0.556
3
IntAct:EBI-25839678 CCSB
0.556
3
UniProt:Q96LR2 LURA1
0.556
3
UniProt:Q5SXH7-1 PLEKHS1
0.556
3
UniProt:Q9NR21-5 PARP11
0.556
3
UniProt:Q53FD0-2 ZC2HC1C
0.556
3
UniProt:Q5M9N0-2 CCDC158
0.556
3
UniProt:Q9Y6W6 DUSP10
2
DUSP10 [cytosol]
(R-HSA-5675334)
DUSP10 [nucleoplasm]
(R-HSA-203793)
0.556
3
UniProt:Q66PJ3-4 ARL6IP4
0.556
3
UniProt:Q8NDP9 Q8NDP9
0.556
3
IntAct:EBI-25849055 CCSB
0.556
3
UniProt:Q3KNS6-3 Q3KNS63
0.556
3
UniProt:P47804-3 P478043
0.556
3
UniProt:P36406 TRI23
0.556
3
UniProt:Q06547-2 GABPB1
1
NRF2 beta-2 subunit [nucleoplasm]
(R-HSA-1592200)
0.556
3
UniProt:Q5T447-2 Q5T4472
0.556
3
UniProt:Q8IUR5-4 TMTC1
0.556
3
UniProt:Q13404 UBE2V1
1
UBE2V1 [cytosol]
(R-HSA-205753)
0.556
3
UniProt:O43482 OIP5
1
OIP5 [nucleoplasm]
(R-HSA-606286)
0.556
3
UniProt:Q9NPC6 MYOZ2
0.556
3
UniProt:Q9NSI6-4 BRWD1
0.556
3
UniProt:Q9ULD4-2 Q9ULD42
0.556
3
UniProt:Q9BPU6 DPYSL5
3
p-Y-DPYSL5 [cytosol]
(R-HSA-399786)
DPYSL5 [cytosol]
(R-HSA-398138)
p-S534-DPYSL5 [cytosol]
(R-HSA-399793)
0.556
3
UniProt:Q9BXU0 TEX12
1
TEX12 [nucleoplasm]
(R-HSA-912441)
0.556
3
UniProt:Q5W111-2 SPRYD7
0.556
3
UniProt:Q9H2G9 BLZF1
1
BLZF1 [Golgi membrane]
(R-HSA-2422372)
0.556
3
UniProt:Q6ZR37 PKHG7
0.556
3
UniProt:O60830 TIMM17B
2
TIMM17B [mitochondrial intermembrane space]
(R-HSA-1955371)
TIMM17B [mitochondrial inner membrane]
(R-HSA-1252138)
0.556
3
UniProt:Q9P1Q0-4 VPS54
0.556
3
UniProt:Q13573 SNW1
1
SNW1 [nucleoplasm]
(R-HSA-351663)
0.556
3
UniProt:Q495U3 Q495U3
0.556
3
UniProt:Q07869 PPARA
2
monoSUMO1-K185-PPARA [nucleoplasm]
(R-HSA-4341099)
PPARA [nucleoplasm]
(R-HSA-400186)
0.556
3
UniProt:Q7Z7F0-4 KHDC4
0.556
3
UniProt:Q9NX94 WBP1L
0.556
3
UniProt:Q6PF05 TT23L
0.556
3
UniProt:O43829 ZBT14
0.556
3
UniProt:Q96FT7-4 ASIC4
0.556
3
UniProt:Q96H12 MSD3
0.556
3
UniProt:Q6ZN54-2 DEF8
0.556
3
UniProt:Q8WUD1-2 Q8WUD12
0.556
3
UniProt:P06454-2 PTMA
0.556
3
UniProt:Q13586 STIM1
1
STIM1 [endoplasmic reticulum membrane]
(R-HSA-434675)
0.556
3
UniProt:O00472 ELL2
1
ELL2 [nucleoplasm]
(R-HSA-6807506)
0.556
3
UniProt:Q96GL9 F163A
0.556
3
IntAct:EBI-25835796 CCSB
0.556
3
IntAct:EBI-25853226 CCSB
0.556
3
UniProt:MGC16703 D3DX41
0.556
3
IntAct:EBI-25835277 CCSB
0.556
3
UniProt:Q3SXR2 CC036
0.556
3
UniProt:Q9NP64 ZCC17
0.556
3
UniProt:Q8WVD3 RNF138
1
RNF138 [cytosol]
(R-HSA-976008)
0.556
3
UniProt:Q6ZMI0-5 PPP1R21
0.556
3
UniProt:Q96JB6 LOXL4
3
LOXL4(25-?) [extracellular region]
(R-HSA-2022087)
LOXL4 [extracellular region]
(R-HSA-2022127)
LOXL4(?-756) [extracellular region]
(R-HSA-2022098)
0.556
3
UniProt:Q6GQQ9-2 Q6GQQ92
0.556
3
UniProt:Q8N0U2 TMM61
0.556
3
UniProt:A0A0A0MR05 A0A0A0MR05
0.556
3
UniProt:P54274-2 TERF1
0.556
3
UniProt:Q8N0U6 CF218
0.556
3
UniProt:Q99743 NPAS2
2
NPAS2 [cytosol]
(R-HSA-400314)
p-S-NPAS2 [nucleoplasm]
(R-HSA-421309)
0.556
3
IntAct:EBI-25835824 RZPDO834E0719D
0.556
3
IntAct:EBI-25837563 CCSB
0.556
3
UniProt:P15407 FOSL1
1
FOSL1 [nucleoplasm]
(R-HSA-9620405)
0.556
3
UniProt:Q9BT25 HAUS8
1
HAUS8 [cytosol]
(R-HSA-8855198)
0.556
3
UniProt:Q496A3 SPAS1
0.556
3
UniProt:Q96JL9-2 Q96JL92
0.556
3
UniProt:Q06323 PSME1
1
PSME1 [cytosol]
(R-HSA-68812)
0.556
3
UniProt:A0AVK6 E2F8
1
E2F8 [nucleoplasm]
(R-HSA-8952990)
0.556
3
UniProt:Q9UJU6 DBNL
7
DBNL [secretory granule lumen]
(R-HSA-6801520)
DBNL [ficolin-1-rich granule lumen]
(R-HSA-6801510)
DBNL [cytosol]
(R-HSA-202880)
DBNL(362-431) [cytosol]
(R-HSA-202933)
DBNL(1-361) [cytosol]
(R-HSA-202925)
DBNL [tertiary granule lumen]
(R-HSA-6801516)
DBNL [extracellular region]
(R-HSA-6801604)
0.556
3
UniProt:Q9NZH6 IL37
6
IL37(?-218) [nucleoplasm]
(R-HSA-9008702)
IL37(1-?) [cytosol]
(R-HSA-9008602)
IL37 [cytosol]
(R-HSA-9008596)
IL37(?-218) [extracellular region]
(R-HSA-9008607)
IL37 [extracellular region]
(R-HSA-8848334)
IL37(?-218) [cytosol]
(R-HSA-9008584)
0.556
3
UniProt:Q86WV5 TEN1
1
TEN1 [nucleoplasm]
(R-HSA-9668823)
0.556
3
UniProt:P10809 HSPD1
6
HSPD1 [mitochondrial matrix]
(R-HSA-1299448)
HSPD1(1-573) [cytosol]
(R-HSA-1267989)
HSPD1(1-573) [mitochondrial intermembrane space]
(R-HSA-1267963)
HSPD1 [mitochondrial inner membrane]
(R-HSA-1299455)
HSPD1(1-573) [mitochondrial inner membrane]
(R-HSA-1299442)
HSPD1(1-26) [mitochondrial matrix]
(R-HSA-8986171)
0.556
3
UniProt:Q7Z7J5 DPPA2
1
DPPA2 [nucleoplasm]
(R-HSA-9816401)
0.556
3
UniProt:O43504 LAMTOR5
1
LAMTOR5 [lysosomal membrane]
(R-HSA-5655441)
0.556
3
UniProt:P62333 PSMC6
2
PSMC6 [nucleoplasm]
(R-HSA-174319)
PSMC6 [cytosol]
(R-HSA-68783)
0.556
3
UniProt:O95674 CDS2
1
CDS2 [mitochondrial inner membrane]
(R-HSA-1498755)
0.556
3
UniProt:P19388 POLR2E
2
POLR2E [nucleoplasm]
(R-HSA-83713)
POLR2E [cytosol]
(R-HSA-1964438)
0.556
3
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