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About
What is Reactome ?
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CLTA [cytosol]
Stable Identifier
R-HSA-8856817
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Synonyms
Clathrin light chain A, CLCA_HUMAN
Locations in the PathwayBrowser
Expand all
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
BAR domain proteins recruit dynamin (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
ARBB recruits GPCRs into clathrin-coated pits (Homo sapiens)
ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Clathrin recruits PIK3C2A (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Clathrin recruits auxilins to the clathrin-coated vesicle (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Dissociation of AAK1 and dephosphorylation of AP-2 mu2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Dissociation of clathrin-associated proteins (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilinGGC-RAB5:GTP:GAPVD1 [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:ITSNs:EPS15:REPS1:NECAPs:AP-2:SGIP1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Dynamin-mediated GTP hydrolysis promotes vesicle scission (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Endophilins recruit synaptojanins to the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
F- and N- BAR domain proteins bind the clathrin-coated pit (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
FCHo proteins bind nascent clathrin-coated pit (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin:HSPA8:ADP [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Initial binding of AP-2 and clathrin to PI(4,5)P2 (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
RAB5 and GAPVD1 bind AP-2 (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Homo sapiens)
Clathrin-coated vesicle [cytosol] (Homo sapiens)
clathrin [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
Recruitment of AP-2 complex and clathrin (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Homo sapiens)
PI(4,5)P2:AP-2:clathrin [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
SNX9 recruits components of the actin polymerizing machinery (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Homo sapiens)
PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Homo sapiens)
PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Homo sapiens)
PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Homo sapiens)
clathrin triskelion [cytosol] (Homo sapiens)
Clathrin light chains [cytosol] (Homo sapiens)
CLTA [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:P09496 CLTA
Gene Names
CLTA
Chain
chain:1-248
Reference Genes
BioGPS Gene:1211 CLTA
COSMIC (genes):CLTA CLTA
CTD Gene:1211 CLTA
dbSNP Gene:1211 CLTA
ENSEMBL:ENSG00000122705.17 CLTA
HGNC:2090 CLTA
KEGG Gene (Homo sapiens):1211 CLTA
Monarch:1211 CLTA
NCBI Gene:1211 CLTA
OMIM:118960 CLTA
UCSC:P09496 CLTA
Reference Transcript
RefSeq:NM_001076677.2 CLTA
RefSeq:NM_001833.3 CLTA
RefSeq:NM_001184760.1 CLTA
RefSeq:NM_007096.3 CLTA
RefSeq:NM_001184762.1 CLTA
Other Identifiers
0002480026
0004810347
11717160_a_at
11742501_a_at
11742504_x_at
11744383_x_at
11745602_s_at
11745603_x_at
11753398_a_at
11753530_a_at
11757289_x_at
1211
17084882
200960_3p_x_at
200960_PM_x_at
200960_x_at
204050_3p_s_at
204050_PM_s_at
204050_s_at
216295_PM_s_at
216295_s_at
3168416
3168417
3168419
3168422
3168426
3168427
3168430
3168431
3403404
38657_s_at
8155203
A_23_P219144
GE80739
GO:0003674
GO:0005198
GO:0005515
GO:0005622
GO:0005737
GO:0005764
GO:0005768
GO:0005773
GO:0005794
GO:0005819
GO:0005829
GO:0005856
GO:0005886
GO:0005905
GO:0006886
GO:0006897
GO:0007049
GO:0016020
GO:0016192
GO:0030118
GO:0030125
GO:0030130
GO:0030132
GO:0030136
GO:0030659
GO:0030672
GO:0031410
GO:0032050
GO:0032588
GO:0032991
GO:0036020
GO:0042277
GO:0043226
GO:0044877
GO:0045334
GO:0048268
GO:0051020
GO:0051301
GO:0065003
GO:0071439
GO:0072583
GO:0098835
GO:0099631
HMNXSV003046448
Hs.285688.0.S1_3p_s_at
ILMN_1687171
ILMN_1695420
ILMN_2345837
M20471_at
PH_hs_0023037
TC09000204.hg
g4502898_3p_a_at
g6005992_3p_a_at
Participates
as a component of
clathrin [cytosol] (Homo sapiens)
as a member of
Clathrin light chains [cytosol] (Homo sapiens)
Other forms of this molecule
CLTA [trans-Golgi network membrane]
CLTA [endolysosome membrane]
CLTA [clathrin-coated endocytic vesicle membrane]
CLTA [lysosomal membrane]
CLTA [plasma membrane]
Inferred To
clc1 [cytosol]
(Schizosaccharomyces pombe)
clta [cytosol]
(Xenopus tropicalis)
CLC1 [cytosol]
(Saccharomyces cerevisiae)
CLTA [cytosol]
(Bos taurus)
CLTA [cytosol]
(Gallus gallus)
CLTA [cytosol]
(Sus scrofa)
clc [cytosol]
(Dictyostelium discoideum)
clic-1 [cytosol]
(Caenorhabditis elegans)
Clc [cytosol]
(Drosophila melanogaster)
Clta [cytosol]
(Mus musculus)
Clta [cytosol]
(Rattus norvegicus)
Clathrin light chain [cytosol]
(Canis familiaris)
Clathrin light chain [cytosol]
(Danio rerio)
Cross References
RefSeq
NP_001070145.1
,
NP_001824.1
,
NP_001171691.1
,
NP_009027.1
,
NP_001171689.1
OpenTargets
ENSG00000122705
GeneCards
P09496
HPA
ENSG00000122705-CLTA
Ensembl
ENST00000396603
,
ENSP00000242285
,
ENSP00000242284
,
ENST00000470744
,
ENST00000345519
,
ENSP00000379848
,
ENSP00000437508
,
ENSG00000122705
,
ENST00000242285
,
ENSP00000419746
,
ENST00000540080
PRO
P09496
Pharos - Targets
P09496
PDB
6E5N
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9Y6A5 TACC3
1
TACC3 [cytosol]
(R-HSA-2160956)
0.499
3
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