Reactome | Clathrin light chain [cytosol]

Clathrin light chain [cytosol]

Stable Identifier

R-SSC-350828

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

cytosol

Synonyms

A0A287A682

Locations in the PathwayBrowser

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Vesicle-mediated transport (Sus scrofa)

- Membrane Trafficking (Sus scrofa)
  - Clathrin-mediated endocytosis (Sus scrofa)
    - AAK1 phosphorylates AP-2 mu subunit at T156 (Sus scrofa)
      - PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1 [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:AP-2:clathrin [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Auxilin recruits HSPA8:ATP to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - BAR domain proteins recruit dynamin (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - CLASP proteins and cargo are recruited to the nascent clathrin-coated pit (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Cargo recognition for clathrin-mediated endocytosis (Sus scrofa)
      - ARBB recruits GPCRs into clathrin-coated pits (Sus scrofa)
        
        ARBBs:ARBB-binding GPCRs:clathrin-coated pit [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Clathrin recruits PIK3C2A (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Clathrin recruits auxilins to the clathrin-coated vesicle (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Dynamin-mediated GTP hydrolysis promotes vesicle scission (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Endophilins recruit synaptojanins to the clathrin-coated pit (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - F- and N- BAR domain proteins bind the clathrin-coated pit (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:PIK3C2A [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:FCHO1,2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1 [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
      - PI(4)P:p-T156 AP-2:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GDP:SYNJs:auxilin:HSPA8:ATP [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        CLASP proteins:cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EPS15,EPN1,EPN2:ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        ubiquitinated cargo [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        EGF-like ligands:p-6Y-EGFR:p-Y371-CBL:GRB2:CIN85:Endophilin:Epsin:EPS15L1:p-EPS15:HGS:STAM:Clathrin [clathrin-coated endocytic vesicle membrane] (Sus scrofa)
        
        Clathrin-coated vesicle [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - clathrin:HSPA8:ADP [cytosol] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Initial binding of AP-2 and clathrin to PI(4,5)P2 (Sus scrofa)
      - PI(4,5)P2:AP-2:clathrin [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - SNX9 recruits components of the actin polymerizing machinery (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - SYNJ hydrolyze PI(4,5)P2 to PI(4)P (Sus scrofa)
      - PI(4)P:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP:SYNJs [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers:DNM:GTP [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins:ARP2/3 complex:WASL:f-actin:HIP dimers [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:p-T156 AP-2:clathrin:ITSNs:EPS15:REPS1:SGIP1:NECAPs:AAK1:CLASP proteins:cargo:F-BAR proteins:BAR domain proteins [plasma membrane] (Sus scrofa)
        
        PI(4,5)P2:ITSNs:EPS15:REPS1:clathrin:NECAPs:p-T156 AP-2:SGIP1:CLASP proteins:cargo [plasma membrane] (Sus scrofa)
        
        clathrin triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chains [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
  - trans-Golgi Network Vesicle Budding (Sus scrofa)
    - Golgi Associated Vesicle Biogenesis (Sus scrofa)
      - trans-Golgi Network Coat Assembly (Sus scrofa)
        
        Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - trans-Golgi Network Derived Vesicle Uncoating (Sus scrofa)
        
        Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - trans-Golgi Network Vesicle Scission (Sus scrofa)
        
        Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [cytoplasmic vesicle membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
    - Lysosome Vesicle Biogenesis (Sus scrofa)
      - trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [lysosomal membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - trans-Golgi Network Lysosomal Vesicle Scission (Sus scrofa)
        
        Lysosome Cargo:AP-1:Beta-arrestin:Clathrin Triskelion:Vamp Complex [lysosomal membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
      - trans-Golgi Network Lysosome Vesicle Destined Membrane Coat Assembly (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)
        
        Lysosome Destined Cargo:AP-1:Beta-arrestin:Vamp:Clathrin Triskelion:Dynamin:Endophilin Complex [Golgi membrane] (Sus scrofa)
        
        Clathrin Triskelion [cytosol] (Sus scrofa)
        
        Clathrin light chain [cytosol] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287A682

Reference Genes

ENSEMBL:ENSSSCG00000037131

Other Identifiers

GO:0003674

GO:0005198

GO:0005575

GO:0005622

GO:0005623

GO:0005737

GO:0005794

GO:0005886

GO:0005905

GO:0006810

GO:0006886

GO:0008150

GO:0015031

GO:0016020

GO:0016192

GO:0022607

GO:0030118

GO:0030125

GO:0030130

GO:0030132

GO:0030659

GO:0030672

GO:0031410

GO:0032050

GO:0032991

GO:0043226

GO:0048268

GO:0065003

GO:0071439

GO:0072583

GO:0099631

Ssc.11113.1.S1_at

Participant Of

hasMember

Clathrin light chains [cytosol]

hasComponent

Clathrin Triskelion [cytosol]

Other forms of this molecule

CLTA [lysosomal membrane]

Clathrin light chain [trans-Golgi network membrane]

CLTA [endolysosome membrane]

CLTA [clathrin-coated endocytic vesicle membrane]

CLTA [plasma membrane]

Inferred From

Clathrin light chain [cytosol] (Homo sapiens)

CLTA [cytosol] (Homo sapiens)

Cross References

Ensembl

ENSSSCP00000039273, ENSSSCT00000045598, ENSSSCG00000037131