Reactome | GINS3 [nucleoplasm]

GINS3 [nucleoplasm]

Stable Identifier

R-HSA-5688046

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

DNA replication complex GINS protein PSF3, PSF3_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q9BRX5 GINS3

Gene Names

GINS3, PSF3

Chain

chain:1-216

Reference Genes

BioGPS Gene:64785 GINS3

COSMIC (genes):GINS3 GINS3

CTD Gene:64785 GINS3

dbSNP Gene:64785 GINS3

ENSEMBL:ENSG00000181938 GINS3

ENSEMBL:ENSG00000181938.14 GINS3

HGNC:25851 GINS3

KEGG Gene (Homo sapiens):64785 GINS3

Monarch:64785 GINS3

NCBI Gene:64785 GINS3

OMIM:610610 GINS3

UCSC:Q9BRX5 GINS3

Reference Transcript

Other Identifiers

11739763_a_at

16819678

218719_PM_s_at

218719_s_at

3663233

3663234

3663235

3663238

3663241

3663242

3663246

3663247

3663248

3663249

3663250

3663251

45633_PM_at

45633_at

64785

7996211

A_23_P152136

A_24_P159323

GE56695

GO:0000228

GO:0000278

GO:0000811

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0006260

GO:0006268

GO:0043226

GO:0071162

GO:1900264

GO:1902975

GO:1903934

HMNXSV003006594

ILMN_1754272

PH_hs_0003351

TC16000502.hg

g12232448_3p_s_at

Participates

as a component of

GINS complex [nucleoplasm] (Homo sapiens)

as an input of

Formation of GINS complex (Homo sapiens)

Inferred To

psf3 [nucleoplasm] (Schizosaccharomyces pombe)

Gins3 [nucleoplasm] (Mus musculus)

Gins3 [nucleoplasm] (Rattus norvegicus)

PSF3 [nucleoplasm] (Saccharomyces cerevisiae)

GINS3 [nucleoplasm] (Bos taurus)

GINS3 [nucleoplasm] (Canis familiaris)

GINS3 [nucleoplasm] (Danio rerio)

GINS3 [nucleoplasm] (Gallus gallus)

GINS3 [nucleoplasm] (Sus scrofa)

Psf3 [nucleoplasm] (Drosophila melanogaster)

gins3 [nucleoplasm] (Dictyostelium discoideum)

gins3 [nucleoplasm] (Xenopus tropicalis)

psf-3 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001119602.1, NP_001119601.1, NP_073607.2

OpenTargets

ENSG00000181938

GeneCards

Q9BRX5

HPA

ENSG00000181938-GINS3

Ensembl

ENSP00000318196, ENSP00000401018, ENSP00000327449, ENSG00000181938, ENST00000318129, ENST00000328514, ENST00000426538

PRO

Q9BRX5

Pharos - Targets

Q9BRX5

PDB

6XTY, 7PLO, 6XTX, 2EHO, 2E9X, 2Q9Q, 7PFO

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q14691 GINS1	1	GINS1 [nucleoplasm] (R-HSA-176955)	0.801	7
UniProt:Q08AM6 VAC14	3	VAC14 [Golgi membrane] (R-HSA-1806235) VAC14 [early endosome membrane] (R-HSA-1806207) VAC14 [late endosome membrane] (R-HSA-1806219)	0.718	6
UniProt:P14927 UQCRB	1	UQCRB [mitochondrial inner membrane] (R-HSA-164287)	0.556	3
UniProt:Q96GM5 SMARCD1	1	SMARCD1 [nucleoplasm] (R-HSA-389255)	0.556	3
UniProt:Q6KB66-2 KRT80			0.556	3
UniProt:O75865-2 TRAPPC6A			0.556	3
UniProt:A0A024R8L2 A0A024R8L2			0.556	3
UniProt:Q9UMF0 ICAM5	1	ICAM5 [plasma membrane] (R-HSA-197684)	0.556	3
UniProt:Q9UI47-2 CTNNA3			0.556	3
UniProt:O75190-2 DNAJB6			0.556	3
UniProt:O14901 KLF11			0.556	3
UniProt:O14645 IDLC			0.556	3
UniProt:Q9BVL2 NUP58			0.556	3
UniProt:P46379-2 BAG6			0.556	3

Cite Us!