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ICAM5 [plasma membrane]
Stable Identifier
R-HSA-197684
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Intercellular adhesion molecule-5 precursor, ICA5_HUMAN
Locations in the PathwayBrowser
Expand all
Extracellular matrix organization (Homo sapiens)
Integrin cell surface interactions (Homo sapiens)
ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM5 [plasma membrane] (Homo sapiens)
LFA-1:ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM5 [plasma membrane] (Homo sapiens)
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell (Homo sapiens)
ICAM1-5 bind Integrin alphaLbeta2 (LFA-1) (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM5 [plasma membrane] (Homo sapiens)
LFA-1:ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM 1-5 [plasma membrane] (Homo sapiens)
ICAM5 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9UMF0 ICAM5
Gene Names
ICAM5, TLCN, TLN
Chain
signal peptide:1-31, chain:32-924
Reference Genes
BioGPS Gene:7087 ICAM5
COSMIC (genes):ICAM5 ICAM5
CTD Gene:7087 ICAM5
dbSNP Gene:7087 ICAM5
ENSEMBL:ENSG00000105376 ICAM5
HGNC:5348 ICAM5
KEGG:hsa:7087 ICAM5
Monarch:7087 ICAM5
NCBI Gene:7087 ICAM5
OMIM:601852 ICAM5
UCSC:Q9UMF0 ICAM5
Reference Transcript
RefSeq:XM_011528229.1 ICAM5
RefSeq:NM_003259.3 ICAM5
Other Identifiers
11734245_at
11761417_at
16858156
206906_PM_at
206906_at
3820470
3820471
3820472
3820473
3820474
3820475
3820476
3820477
3820478
3820479
3820480
3820482
3820483
3820484
3820486
3820487
3820489
3820490
3820491
3820492
3820493
3820497
40209_at
7087
8025621
A_14_P114513
A_23_P119143
A_24_P254079
GE81255
GO:0005178
GO:0005515
GO:0005886
GO:0006909
GO:0007155
GO:0016020
GO:0016192
GO:0051963
GO:0098609
GO:0098794
GO:0098978
ILMN_1802524
PH_hs_0009117
TC19000176.hg
U72671_at
g12545403_3p_at
Participates
as a member of
ICAM 1-5 [plasma membrane] (Homo sapiens)
Inferred To
si:ch73-208g10.1 [plasma membrane]
(Danio rerio)
Icam5 [plasma membrane]
(Mus musculus)
Icam5 [plasma membrane]
(Rattus norvegicus)
ICAM5 [plasma membrane]
(Bos taurus)
ICAM5 [plasma membrane]
(Canis familiaris)
ICAM5 [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_003250.3
,
XP_011526531.1
ENSEMBL
ENST00000221980
,
ENSP00000221980
OpenTargets
ENSG00000105376
HPA
ENSG00000105376-ICAM5
PRO
Q9UMF0
Pharos - Targets
Q9UMF0
GlyGen
Q9UMF0
PDB
4OIB
,
4OIA
,
3BN3
,
4OI9
Interactors (8)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P05094
3
ACTN1 [extracellular region]
(R-GGA-349722)
ACTN1 [platelet alpha granule lumen]
(R-GGA-349724)
ACTN1 [cytosol]
(R-GGA-354096)
0.602
3
UniProt:P13196 ALAS1
2
PXLP-ALAS1 [mitochondrial matrix]
(R-HSA-1022086)
ALAS1 [mitochondrial matrix]
(R-HSA-189438)
0.556
3
UniProt:Q8WY64 MYLIP
1
MYLIP [cytosol]
(R-HSA-8850908)
0.556
3
UniProt:P05067 APP
20
APP(672-713) [extracellular region]
(R-HSA-879340)
APP(672-711) [cytosol]
(R-HSA-877188)
APP(672-711) [extracellular region]
(R-HSA-976740)
APP [endoplasmic reticulum lumen]
(R-HSA-8956696)
p-APP [endoplasmic reticulum lumen]
(R-HSA-8957012)
APP(18-770) [endosome lumen]
(R-HSA-5229077)
APP(672-711) [endosome lumen]
(R-HSA-6783333)
APP(672-713) [endosome lumen]
(R-HSA-5692993)
APP(672-770) [endosome lumen]
(R-HSA-9010082)
APP(712-770) [endosome lumen]
(R-HSA-6783331)
APP(714-770) [endosome lumen]
(R-HSA-6783325)
APP(18-671) [endosome lumen]
(R-HSA-5693003)
APP(18-770) [plasma membrane]
(R-HSA-9010038)
APP(18-770) [Golgi lumen]
(R-HSA-8871509)
APP(688-770) [plasma membrane]
(R-HSA-9010028)
APP(18-687) [extracellular region]
(R-HSA-9010033)
APP(18-770) [platelet alpha granule lumen]
(R-HSA-139835)
APP(18-770) [extracellular region]
(R-HSA-49335)
APP-C99 [cytosol]
(R-HSA-9617603)
APP(18-770) [trans-Golgi network membrane]
(R-HSA-5229136)
0.556
3
UniProt:Q13887 KLF5
1
KLF5 [nucleoplasm]
(R-HSA-381279)
0.556
3
UniProt:Q9BRX5 GINS3
1
GINS3 [nucleoplasm]
(R-HSA-5688046)
0.556
3
UniProt:P02795 MT2A
1
MT2A [cytosol]
(R-HSA-1031707)
0.556
3
UniProt:O75528 TADA3
1
TADA3 [nucleoplasm]
(R-HSA-3322966)
0.556
3
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