Reactome | GINS1 [nucleoplasm]

GINS1 [nucleoplasm]

Stable Identifier

R-HSA-176955

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

PSF1p

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q14691 GINS1

Gene Names

GINS1, KIAA0186, PSF1

Chain

chain:1-196

Reference Genes

BioGPS Gene:9837 GINS1

COSMIC (genes):GINS1 GINS1

CTD Gene:9837 GINS1

dbSNP Gene:9837 GINS1

ENSEMBL:ENSG00000101003 GINS1

HGNC:28980 GINS1

KEGG:hsa:9837 GINS1

Monarch:9837 GINS1

NCBI Gene:9837 GINS1

OMIM:610608 GINS1

UCSC:Q14691 GINS1

Reference Transcript

RefSeq:NM_021067.4 GINS1

Other Identifiers

11728863_at

11728864_at

11749970_a_at

16912192

206102_PM_at

206102_at

3880828

3880829

3880830

3880832

3880833

3880834

3880835

3880836

3880838

3880839

3880840

3880841

3880842

3880843

3880844

3880845

3880846

3880847

39677_at

8061471

89352_at

9837

A_14_P104044

A_14_P119966

A_14_P134876

A_23_P210853

A_33_P3340025

D80008_at

GE61202

GO:0000811

GO:0001833

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0006260

GO:0006268

GO:0043226

GO:0071162

GO:1902983

HMNXSV003030589

HMNXSV003036249

ILMN_1697751

PH_hs_0024018

RNA95639|RNS_721_133

TC20000169.hg

g10800147_3p_at

Participates

as a component of

GINS complex [nucleoplasm] (Homo sapiens)

as an input of

Formation of GINS complex (Homo sapiens)

Inferred To

PSF1 [nucleoplasm] (Saccharomyces cerevisiae)

psf-1 [nucleoplasm] (Caenorhabditis elegans)

GINS1 [nucleoplasm] (Bos taurus)

GINS1 [nucleoplasm] (Canis familiaris)

GINS1 [nucleoplasm] (Gallus gallus)

GINS1 [nucleoplasm] (Rattus norvegicus)

GINS1 [nucleoplasm] (Sus scrofa)

gins1 [nucleoplasm] (Danio rerio)

gins1 [nucleoplasm] (Dictyostelium discoideum)

gins1 [nucleoplasm] (Xenopus tropicalis)

psf1 [nucleoplasm] (Schizosaccharomyces pombe)

Psf1 [nucleoplasm] (Drosophila melanogaster)

Gins1 [nucleoplasm] (Mus musculus)

Cross References

RefSeq

NP_066545.3

ENSEMBL

ENST00000696874, ENST00000262460, ENSP00000262460, ENSG00000101003, ENSP00000512943

OpenTargets

ENSG00000101003

GeneCards

GINS1

HPA

ENSG00000101003-GINS1

PRO

Q14691

Pharos - Targets

Q14691

GlyGen

Q14691

Orphanet

GINS1

PDB

6XTY, 6XTX, 7PLO, 8B9D, 2EHO, 8OK2, 7PFO, 2E9X, 2Q9Q

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BRX5 GINS3	1	GINS3 [nucleoplasm] (R-HSA-5688046)	0.846	10
UniProt:Q9BRT9 GINS4	1	GINS4 [nucleoplasm] (R-HSA-176963)	0.813	8
UniProt:Q9Y248 GINS2	1	GINS2 [nucleoplasm] (R-HSA-176975)	0.801	8
UniProt:O75419 CDC45	1	CDC45 [nucleoplasm] (R-HSA-68563)	0.623	4
UniProt:Q9NYP3 DONS			0.584	7
UniProt:Q86UT8 CATAC			0.527	3
UniProt:P29084 GTF2E2	1	GTF2E2 [nucleoplasm] (R-HSA-65563)	0.527	2
UniProt:Q9BVW5 TIPIN	1	TIPIN [nucleoplasm] (R-HSA-5684983)	0.527	2
UniProt:P33993 MCM7	1	MCM7 [nucleoplasm] (R-HSA-68555)	0.527	3
UniProt:P78368 CSNK1G2	2	CSNK1G2 [cytosol] (R-HSA-429696) CSNK1G2 [plasma membrane] (R-HSA-205718)	0.527	2
UniProt:P33992 MCM5	1	MCM5 [nucleoplasm] (R-HSA-68551)	0.527	2