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TIPIN [nucleoplasm]
Stable Identifier
R-HSA-5684983
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
TIMELESS-interacting protein
Locations in the PathwayBrowser
Expand all
DNA Repair (Homo sapiens)
DNA Double-Strand Break Repair (Homo sapiens)
Homology Directed Repair (Homo sapiens)
HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA) (Homo sapiens)
Processing of DNA double-strand break ends (Homo sapiens)
Activation of CHEK1 at resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
CHEK1 is recruited to resected DNA DSBs (Homo sapiens)
ATR:ATRIP:p-RPA:3' overhanging ssDNA-DSBs:p-MRN:p-S1981,Ac-K3016-ATM:KAT5:BRCA1-C complex:EXO1,DNA2:BLM,WRN:p-S990,Ac-K1249-BRIP1:RAD17:RFC:RAD9:HUS1:RAD1:RHNO1:TOPBP1:TIMELESS:TIPIN:p-T916,S945-CLSPN:CHEK1 [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
TIPIN [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9BVW5 TIPIN
Gene Names
TIPIN
Chain
chain:1-301
Reference Genes
BioGPS Gene:54962 TIPIN
COSMIC (genes):TIPIN TIPIN
CTD Gene:54962 TIPIN
dbSNP Gene:54962 TIPIN
ENSEMBL:ENSG00000075131 TIPIN
HGNC:30750 TIPIN
KEGG:hsa:54962 TIPIN
Monarch:54962 TIPIN
NCBI Gene:54962 TIPIN
OMIM:610716 TIPIN
UCSC:Q9BVW5 TIPIN
Reference Transcript
RefSeq:XM_017022390.1 TIPIN
RefSeq:XM_011521743.1 TIPIN
RefSeq:XM_006720594.3 TIPIN
RefSeq:NM_001289986.1 TIPIN
RefSeq:XM_005254522.4 TIPIN
RefSeq:XM_005254521.2 TIPIN
RefSeq:NM_017858.2 TIPIN
Other Identifiers
11715237_s_at
11727081_a_at
11761621_at
11761622_x_at
16810933
18670033
18670038
18670039
219258_PM_at
219258_at
2766433
2959271
2959276
3559677
3630100
3630101
3630102
3630103
3630105
3630106
3630107
3630108
3630109
3630110
3630111
3630112
3630114
3630115
3630116
3630117
3630118
3630120
3630121
3630122
3630123
3635869
3693513
3857880
3857883
3857884
4009309
4009312
43381_s_at
54962
64738_at
7895994
7989915
80574_s_at
A_23_P99930
GE82236
GO:0000076
GO:0000077
GO:0000785
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005737
GO:0006974
GO:0008284
GO:0009411
GO:0031297
GO:0031298
GO:0031573
GO:0033262
GO:0043111
GO:0043226
GO:0044770
GO:0051301
HMNXSV003001308
HMNXSV003014709
ILMN_1761939
ILMN_1769277
PH_hs_0035946
TC15001576.hg
U09953_at
g8923484_3p_at
Participates
as a component of
TIMELESS:TIPIN [nucleoplasm] (Homo sapiens)
Inferred To
Tipin [nucleoplasm]
(Mus musculus)
Tipin [nucleoplasm]
(Rattus norvegicus)
CSM3 [nucleoplasm]
(Saccharomyces cerevisiae)
Homologues of TIPIN [nucleoplasm]
(Rattus norvegicus)
tipn-1 [nucleoplasm]
(Caenorhabditis elegans)
TIPIN [nucleoplasm]
(Bos taurus)
TIPIN [nucleoplasm]
(Canis familiaris)
TIPIN [nucleoplasm]
(Drosophila melanogaster)
TIPIN [nucleoplasm]
(Gallus gallus)
TIPIN [nucleoplasm]
(Sus scrofa)
swi3 [nucleoplasm]
(Schizosaccharomyces pombe)
Cross References
RefSeq
NP_060328.2
,
NP_001276915.1
,
XP_016877879.1
,
XP_006720657.1
,
XP_005254578.1
,
XP_005254579.1
,
XP_011520045.1
ENSEMBL
ENST00000261881
,
ENSP00000261881
,
ENSG00000075131
OpenTargets
ENSG00000075131
GeneCards
TIPIN
HPA
ENSG00000075131-TIPIN
PRO
Q9BVW5
Pharos - Targets
Q9BVW5
PDB
7PLO
,
8B9D
,
7PFO
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:Q9BRX5 GINS3
1
GINS3 [nucleoplasm]
(R-HSA-5688046)
0.527
2
UniProt:Q14691 GINS1
1
GINS1 [nucleoplasm]
(R-HSA-176955)
0.527
2
UniProt:Q9BRT9 GINS4
1
GINS4 [nucleoplasm]
(R-HSA-176963)
0.527
2
UniProt:P33993 MCM7
1
MCM7 [nucleoplasm]
(R-HSA-68555)
0.527
2
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