Reactome | ELOVL4 [endoplasmic reticulum membrane]

ELOVL4 [endoplasmic reticulum membrane]

Stable Identifier

R-HSA-548705

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

endoplasmic reticulum membrane

Synonyms

Elongation of very long chain fatty acids protein 4

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q9GZR5 ELOVL4

Gene Names

ELOVL4

Chain

chain:1-314

Reference Genes

BioGPS Gene:6785 ELOVL4

COSMIC (genes):ELOVL4 ELOVL4

CTD Gene:6785 ELOVL4

dbSNP Gene:6785 ELOVL4

ENSEMBL:ENSG00000118402 ELOVL4

HGNC:14415 ELOVL4

KEGG:hsa:6785 ELOVL4

Monarch:6785 ELOVL4

NCBI Gene:6785 ELOVL4

OMIM:605512 ELOVL4

UCSC:Q9GZR5 ELOVL4

Reference Transcript

RefSeq:NM_022726.4 ELOVL4

Other Identifiers

11726590_at

11726591_s_at

11763852_a_at

17021083

219532_PM_at

219532_at

2962114

2962115

2962116

2962118

2962119

2962120

2962121

2962122

2962126

2962127

58015_at

6785

74321_at

8127767

A_23_P82065

GE62105

GO:0005515

GO:0005783

GO:0005789

GO:0006629

GO:0006631

GO:0006633

GO:0006636

GO:0006790

GO:0008020

GO:0009584

GO:0009922

GO:0016020

GO:0016740

GO:0019367

GO:0030148

GO:0030497

GO:0034625

GO:0034626

GO:0035338

GO:0042761

GO:0055086

HMNXSV003003193

ILMN_1737965

PH_hs_0005663

TC06001902.hg

g12232378_3p_at

Participates

as a member of

ELOVL1,4 [endoplasmic reticulum membrane] (Homo sapiens)

Cross References

RefSeq

NP_073563.1

OpenTargets

ENSG00000118402

ENSEMBL

ENSP00000358831, ENSG00000118402, ENST00000369816

HPA

ENSG00000118402-ELOVL4

GeneCards

ELOVL4

PRO

Q9GZR5

Pharos - Targets

Q9GZR5

Orphanet

ELOVL4

GlyGen

Q9GZR5

HMDB Protein

HMDBP04479

Interactors (23)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P09601 HMOX1	4	HMOX1 [cytosol] (R-HSA-9609901) HMOX1 [endoplasmic reticulum membrane] (R-HSA-189395) HMOX1 [mitochondrial outer membrane] (R-HSA-9708524) HMOX1 [nucleoplasm] (R-HSA-9708567)	0.556	3
UniProt:O75379 VAMP4	4	VAMP4 [plasma membrane] (R-HSA-8864461) VAMP4 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869133) VAMP4 [transport vesicle] (R-HSA-6811023) VAMP4 [trans-Golgi network membrane] (R-HSA-6811021)	0.556	3
UniProt:O75396 SEC22B	6	SEC22B [ER to Golgi transport vesicle membrane] (R-HSA-5688565) SEC22B [endoplasmic reticulum membrane] (R-HSA-5688150) SEC22B [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688566) SEC22B [phagocytic vesicle membrane] (R-HSA-8863938) SEC22B [transport vesicle] (R-HSA-6810994) SEC22B [Golgi membrane] (R-HSA-6810993)	0.556	3
UniProt:Q9H2F3 HSD3B7	1	HSD3B7 [endoplasmic reticulum membrane] (R-HSA-193441)	0.556	3
UniProt:O60883 GPR37L1	1	GPR37L1 [plasma membrane] (R-HSA-5336178)	0.556	3
UniProt:P37268 FDFT1	1	FDFT1 [endoplasmic reticulum membrane] (R-HSA-191369)	0.556	3
UniProt:Q13277 STX3	1	STX3 [plasma membrane] (R-HSA-449131)	0.556	3
UniProt:Q07817 BCL2L1	2	BCL2L1 [mitochondrial outer membrane] (R-HSA-114236) BCL2L1 [cytosol] (R-HSA-50771)	0.556	3
UniProt:P18031 PTPN1	2	PTPN1 [endosome membrane] (R-HSA-9815895) PTPN1 [cytosol] (R-HSA-210625)	0.556	3
UniProt:Q8IWU4 SLC30A8	2	SLC30A8 [Golgi membrane] (R-HSA-9817561) SLC30A8 [secretory granule membrane] (R-HSA-437106)	0.556	3
UniProt:Q8IVQ6 ZDHHC21	1	ZDHHC21 [Golgi membrane] (R-HSA-203757)	0.556	3
UniProt:P02787 TF	6	apoTF [extracellular region] (R-HSA-350754) apoTF [endosome membrane] (R-HSA-917974) TF [endoplasmic reticulum lumen] (R-HSA-8956763) p-TF [endoplasmic reticulum lumen] (R-HSA-8957001) apoTF [clathrin-coated endocytic vesicle membrane] (R-HSA-8869140) TF [secretory granule lumen] (R-HSA-350704)	0.556	3
UniProt:O95070 YIF1A	1	YIF1A [endoplasmic reticulum membrane] (R-HSA-535599)	0.556	3
UniProt:P50281 MMP14	4	MMP14(21-582) [Golgi lumen] (R-HSA-1604689) MMP14 [Golgi lumen] (R-HSA-1604724) MMP14 [plasma membrane] (R-HSA-1442472) MMP14 [Golgi membrane] (R-HSA-9858808)	0.556	3
UniProt:O15155 BET1	3	BET1 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-5688142) BET1 [transport vesicle] (R-HSA-6808719) BET1 [Golgi membrane] (R-HSA-6807743)	0.556	3
UniProt:Q5QGT7 RTP2	2	RTP2 [endoplasmic reticulum membrane] (R-HSA-9752982) RTP2 [plasma membrane] (R-HSA-8939446)	0.556	3
UniProt:Q7L5A8 FA2H	1	FA2H [endoplasmic reticulum membrane] (R-HSA-5693771)	0.556	3
UniProt:Q12981 BNIP1	1	BNIP1 [endoplasmic reticulum membrane] (R-HSA-6810950)	0.556	3
UniProt:O14653 GOSR2	4	GOSR2 [endoplasmic reticulum membrane] (R-HSA-5689451) GOSR2 [ER to Golgi transport vesicle membrane] (R-HSA-5689800) GOSR2 [endoplasmic reticulum-Golgi intermediate compartment membrane] (R-HSA-535472) GOSR2 [Golgi membrane] (R-HSA-6807755)	0.556	3
UniProt:P17152 TMEM11	1	TMEM11 [mitochondrial inner membrane] (R-HSA-8949578)	0.556	3
UniProt:Q15836 VAMP3	6	VAMP3 [recycling endosome membrane] (R-HSA-2029063) VAMP3 [phagocytic vesicle membrane] (R-HSA-2029013) VAMP3 [plasma membrane] (R-HSA-8867599) VAMP3 [clathrin-coated endocytic vesicle membrane] (R-HSA-8869130) VAMP3 [trans-Golgi network membrane] (R-HSA-6814624) VAMP3 [transport vesicle] (R-HSA-6814625)	0.556	3
UniProt:Q8WVV5 BTN2A2	1	BTN2A2 [plasma membrane] (R-HSA-8851047)	0.556	3
UniProt:P30825 SLC7A1	1	SLC7A1 [plasma membrane] (R-HSA-375771)	0.527	2

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