Reactome | ARID2 [nucleoplasm]

ARID2 [nucleoplasm]

Stable Identifier

R-HSA-5225613

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

AT-rich interactive domain-containing protein 2, ARID2_HUMAN

Locations in the PathwayBrowser

Expand all

Gene expression (Transcription) (Homo sapiens)

- RNA Polymerase II Transcription (Homo sapiens)
  - Generic Transcription Pathway (Homo sapiens)
    - Transcriptional regulation by RUNX1 (Homo sapiens)
      - RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known (Homo sapiens)
        
        RUNX1 binds the SWI/SNF complex (Homo sapiens)
        
        RUNX1:CBFB:SWI/SNF [nucleoplasm] (Homo sapiens)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
        
        SWI/SNF additional components [nucleoplasm] (Homo sapiens)
        
        ARID2 [nucleoplasm] (Homo sapiens)
        
        SWI/SNF chromatin remodelling complex [nucleoplasm] (Homo sapiens)
        
        SWI/SNF additional components [nucleoplasm] (Homo sapiens)
        
        ARID2 [nucleoplasm] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q68CP9 ARID2

Gene Names

ARID2, BAF200, KIAA1557

Chain

initiator methionine:, chain:2-1835

Reference Genes

BioGPS Gene:196528 ARID2

COSMIC (genes):ARID2 ARID2

CTD Gene:196528 ARID2

dbSNP Gene:196528 ARID2

ENSEMBL:ENSG00000189079 ARID2

HGNC:18037 ARID2

KEGG:hsa:196528 ARID2

Monarch:196528 ARID2

NCBI Gene:196528 ARID2

OMIM:609539 ARID2

UCSC:Q68CP9 ARID2

Reference Transcript

Other Identifiers

11734882_a_at

11734883_a_at

11754757_s_at

1553349_PM_at

1553349_at

16750360

196528

225486_PM_at

225486_at

225490_PM_at

225490_at

3412709

3412744

3412746

3412748

3412750

3412752

3412756

3412758

3412760

3412762

3412764

3412766

3412768

3412770

3412772

3412774

3412776

3412778

3412780

3412782

3412784

3412786

3412788

3412790

3412792

3412794

3412796

3412798

3412800

3412802

3412804

3412806

3412808

3412810

3412812

3412819

3412823

3412825

3412827

3412829

3412831

46190_at

49214_s_at

49953_at

7955019

83647_at

A_23_P308464

A_32_P74955

GE61960

GE897224

GO:0000776

GO:0000785

GO:0003007

GO:0003677

GO:0005515

GO:0005634

GO:0005654

GO:0005886

GO:0006325

GO:0006337

GO:0006338

GO:0006355

GO:0006357

GO:0008285

GO:0016363

GO:0016514

GO:0016586

GO:0030071

GO:0030336

GO:0042592

GO:0043226

GO:0045582

GO:0045597

GO:0045663

GO:0046872

GO:0048568

GO:0048856

GO:0060038

GO:0060982

GO:0070316

GO:0072359

GO:1905168

GO:2000045

GO:2000781

GO:2000819

HMNXSV003012307

Hs.6185.1.A1_3p_at

Hs.6185.1.A2_3p_at

Hs2.379904.1.S1_3p_at

ILMN_1795247

ILMN_2182335

PH_hs_0023769

PH_hs_0041136

TC12000331.hg

Participates

as an input of

ARID2 binds SMARCC dimer:SMARCDs:SMARCE1:SMARCB1 (Homo sapiens)

as a component of

as a candidate of

SWI/SNF additional components [nucleoplasm] (Homo sapiens)

Inferred To

Ghost homologue of ARID2 [nucleoplasm] (Bos taurus)

Ghost homologue of ARID2 [nucleoplasm] (Caenorhabditis elegans)

Ghost homologue of ARID2 [nucleoplasm] (Canis familiaris)

Ghost homologue of ARID2 [nucleoplasm] (Dictyostelium discoideum)

Ghost homologue of ARID2 [nucleoplasm] (Drosophila melanogaster)

Ghost homologue of ARID2 [nucleoplasm] (Gallus gallus)

Ghost homologue of ARID2 [nucleoplasm] (Mus musculus)

Ghost homologue of ARID2 [nucleoplasm] (Rattus norvegicus)

Ghost homologue of ARID2 [nucleoplasm] (Sus scrofa)

Cross References

ENSEMBL

ENST00000334344, ENSP00000335044, ENSG00000189079

OpenTargets

ENSG00000189079

GeneCards

ARID2

HPA

ENSG00000189079-ARID2

PRO

Q68CP9

Pharos - Targets

Q68CP9

GlyGen

Q68CP9

Orphanet

ARID2

PDB

7VDV, 7Y8R

Interactors (11)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q12824 SMARCB1	1	SMARCB1 [nucleoplasm] (R-HSA-389261)	0.89	14
UniProt:P51532 SMARCA4	1	SMARCA4 [nucleoplasm] (R-HSA-201686)	0.767	10
UniProt:Q969G3 SMARCE1	1	SMARCE1 [nucleoplasm] (R-HSA-389258)	0.748	7
UniProt:Q86U86 PBRM1	1	PBRM1 [nucleoplasm] (R-HSA-389254)	0.612	5
UniProt:Q8WUZ0 BCL7C	1	BCL7C [nucleoplasm] (R-HSA-9727457)	0.527	4
UniProt:Q8TAQ2 SMARCC2	1	SMARCC2 [nucleoplasm] (R-HSA-389263)	0.527	3
UniProt:Q92922 SMARCC1	1	SMARCC1 [nucleoplasm] (R-HSA-389257)	0.527	2
UniProt:P52294 KPNA1	2	KPNA1 [cytosol] (R-HSA-180612) KPNA1 [nucleoplasm] (R-HSA-188865)	0.527	2
UniProt:Q13952 NFYC	1	NFYC [nucleoplasm] (R-HSA-981546)	0.519	2
UniProt:Q83D60 Q83D60			0.488	2
UniProt:Q969G2 LHX4	1	LHX4 [nucleoplasm] (R-HSA-9010585)	0.483	2