Reactome | SET [nucleoplasm]

SET [nucleoplasm]

Stable Identifier

R-HSA-451201

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Protein SET, SET_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q01105 SET

Gene Names

SET

Chain

initiator methionine:, chain:2-290

Reference Genes

BioGPS Gene:6418 SET

COSMIC (genes):SET SET

CTD Gene:6418 SET

dbSNP Gene:6418 SET

ENSEMBL:ENSG00000119335 SET

ENSEMBL_homo_sapiens_GENE:ENSG00000119335.18 SET

HGNC:10760 SET

KEGG Gene (Homo sapiens):6418 SET

Monarch:6418 SET

NCBI Gene:6418 SET

OMIM:600960 SET

UCSC:Q01105 SET

Reference Transcript

Other Identifiers

11715769_a_at

11715770_x_at

11733095_s_at

200630_PM_x_at

200630_x_at

200631_3p_s_at

200631_PM_s_at

200631_s_at

210231_PM_x_at

210231_x_at

213047_PM_x_at

213047_x_at

215780_3p_s_at

215780_PM_s_at

215780_s_at

2648928

3190660

3190661

3190663

3190664

3190665

3190668

3190670

3190672

3190675

3190677

3190678

3190679

3190680

3190681

3190682

3535474

3764458

3988214

40189_PM_at

40189_at

6418

7917674

8158372

A_23_P217015

GO:0000785

GO:0003677

GO:0003682

GO:0004864

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005737

GO:0005783

GO:0005811

GO:0005829

GO:0006260

GO:0006325

GO:0006334

GO:0006337

GO:0006351

GO:0006355

GO:0012501

GO:0019888

GO:0032991

GO:0035067

GO:0036211

GO:0042393

GO:0043226

GO:0043524

GO:0045892

GO:0048471

GO:0065003

GO:0098772

HMNXSV003020731

Hs.145279.2.S1_3p_s_at

Hs.248054.0.S1_3p_s_at

ILMN_1742238

M93651_at

PH_hs_0030245

TC05003156.hg

TC09000696.hg

TC09000697.hg

X75091_s_at

g4506890_3p_a_at

g4506890_3p_s_at

g971271_3p_s_at

Participates

as a component of

as an input of

Inferred To

Set [nucleoplasm] (Drosophila melanogaster)

Set [nucleoplasm] (Mus musculus)

Set [nucleoplasm] (Rattus norvegicus)

SET [nucleoplasm] (Bos taurus)

SET [nucleoplasm] (Canis familiaris)

SET [nucleoplasm] (Gallus gallus)

SET [nucleoplasm] (Sus scrofa)

Cross References

RefSeq

NP_001116293.1, NP_001234929.1, NP_003002.2, NP_001234930.1

OpenTargets

ENSG00000119335

HPA

ENSG00000119335-SET

GeneCards

Q01105

Ensembl

ENST00000372692, ENST00000409104, ENSG00000119335, ENST00000322030, ENSP00000387321, ENSP00000509032, ENSP00000361777, ENSP00000318012, ENST00000686840

PRO

Q01105

Pharos - Targets

Q01105

Orphanet

25729

HMDB Protein

HMDBP07996

PDB

7MTO, 2E50

Interactors (20)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q9BT49 THAP7			0.809	7
UniProt:P63000 RAC1	6	RAC1 [ficolin-1-rich granule membrane] (R-HSA-6804802) RAC1 [secretory granule membrane] (R-HSA-6804770) GGC-PalmC-RAC1 [plasma membrane] (R-HSA-2316446) RAC1 [endoplasmic reticulum membrane] (R-HSA-5672076) RAC1 [cytosol] (R-HSA-442615) RAC1 [plasma membrane] (R-HSA-351141)	0.684	8
UniProt:Q6SJ93 F111B			0.666	4
UniProt:P17480 UBTF	2	p-UBTF [nucleoplasm] (R-HSA-76039) UBTF [nucleoplasm] (R-HSA-73683)	0.639	4
UniProt:P20226 TBP	1	TBP [nucleoplasm] (R-HSA-83718)	0.632	4
UniProt:Q15572 TAF1C	1	TAF1C [nucleoplasm] (R-HSA-73687)	0.632	4
UniProt:Q12778 FOXO1	5	p-S218-FOXO1 [nucleoplasm] (R-HSA-5692651) Ac-K245,K248,K265-FOXO1 [nucleoplasm] (R-HSA-9626942) FOXO1 [nucleoplasm] (R-HSA-199300) p-T24,S256,S319-FOXO1 [nucleoplasm] (R-HSA-199306) p-T24,S256,S319-FOXO1 [cytosol] (R-HSA-211158)	0.591	5
UniProt:P68400 CSNK2A1	2	CSNK2A1 [nucleoplasm] (R-HSA-6805057) CSNK2A1 [cytosol] (R-HSA-201713)	0.59	2
UniProt:Q7TSY8	1	Sgo2 [cytosol] (R-MMU-376242)	0.564	3
UniProt:O00560 SDCBP	3	SDCBP [extracellular region] (R-HSA-6806206) SDCBP [azurophil granule lumen] (R-HSA-6799372) SDCBP [cytosol] (R-HSA-373639)	0.556	3
UniProt:P50222 MEOX2			0.556	3
UniProt:P62750 RPL23A	1	RPL23A [cytosol] (R-HSA-72432)	0.527	2
UniProt:Q562F6 SGO2	1	SGOL2 [cytosol] (R-HSA-376242)	0.527	2
UniProt:Q9NVP1 DDX18			0.527	2
UniProt:Q9BWE0 REPI1			0.527	4
UniProt:P10126	6	Me3K79-EEF1A1 [cytosol] (R-MMU-8932212) Me3K318-EEF1A1 [cytosol] (R-MMU-8932419) EEF1A1 [secretory granule lumen] (R-MMU-6801479) EEF1A1 [extracellular region] (R-MMU-6806456) EEF1A1 [ficolin-1-rich granule lumen] (R-MMU-6801528) EEF1A1 [cytosol] (R-MMU-156905)	0.527	2
UniProt:P10644 PRKAR1A	4	PRKAR1A(1-183)-p-7Y-ALK(1058-1620) fusion [cytosol] (R-HSA-9713476) PRKAR1A(1-183)-ALK(1058-1620) fusion [cytosol] (R-HSA-9713471) PRKAR1A [ciliary base] (R-HSA-5610408) PRKAR1A [cytosol] (R-HSA-57836)	0.524	2
UniProt:Q53T94 TAF1B	2	TAF1B [nucleoplasm] (R-HSA-73691) Ac-TAF1B [nucleoplasm] (R-HSA-5138530)	0.524	3
UniProt:Q15573 TAF1A	1	TAF1A [nucleoplasm] (R-HSA-73689)	0.524	2
UniProt:P06454 PTMA			0.508	3

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