HuR binds the CRM1 nuclear export machinery

Stable Identifier
R-HSA-450387
Type
Reaction [binding]
Species
Homo sapiens
Compartment
nucleoplasm
ReviewStatus
5/5
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HuR binds the CRM1 nuclear export machinery
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HuR interacts with SETalpha (Template activating factor 1), SETbeta (CAN/Nup214), APRIL, pp32, and the nuclear export factor CRM1.
Literature References
PubMed ID Title Journal Year
19130553 Phosphorylation of the HuR ligand APRIL by casein kinase 2 regulates CD83 expression

Chemnitz, J, Pieper, D, Grüttner, C, Hauber, J

Eur J Immunol 2009
17178712 Analysis of nucleocytoplasmic trafficking of the HuR ligand APRIL and its influence on CD83 expression

Fries, B, Heukeshoven, J, Hauber, I, Grüttner, C, Stocking, C, Kehlenbach, RH, Hauber, J, Chemnitz, J

J Biol Chem 2007
11018049 Protein ligands to HuR modulate its interaction with target mRNAs in vivo

Brennan, CM, Gallouzi, IE, Steitz, JA

J Cell Biol 2000
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Orthologous Events
HuR binds the CRM1 nuclear export machinery (Bos taurus)
HuR binds the CRM1 nuclear export machinery (Canis familiaris)
HuR binds the CRM1 nuclear export machinery (Drosophila melanogaster)
HuR binds the CRM1 nuclear export machinery (Mus musculus)
HuR binds the CRM1 nuclear export machinery (Rattus norvegicus)
HuR binds the CRM1 nuclear export machinery (Sus scrofa)
Authored
May, B  (2009-12-29)
Reviewed
Wilusz, J  (2010-06-29)
Created
May, B  (2009-12-17)
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