Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Editorial Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Computationally inferred events
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Overlays
DisGeNET
Web
API
Advanced Data Search
Site Search
Community
Icon Library
Outreach
Events
Training
Publications
Partners
Papers Citing Us
Resources Guide
Collaboration
Download
Search ...
Go!
Ac-TAF1B [nucleoplasm]
Stable Identifier
R-HSA-5138530
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
acetylated TAF(1)68
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Transcription of intergenic spacer of the rRNA gene (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
SIRT1 negatively regulates rRNA expression (Homo sapiens)
SIRT1 deacetylates TAF1B in SL1 complex (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Promoter Escape (Homo sapiens)
Elongation of pre-rRNA transcript (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Acetylation of SL1 (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Termination (Homo sapiens)
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q53T94 TAF1B
Gene Names
TAF1B
Chain
chain:1-588
Reference Genes
BioGPS Gene:9014 TAF1B
COSMIC (genes):TAF1B TAF1B
CTD Gene:9014 TAF1B
dbSNP Gene:9014 TAF1B
ENSEMBL:ENSG00000115750.17 TAF1B
HGNC:11533 TAF1B
KEGG Gene (Homo sapiens):9014 TAF1B
Monarch:9014 TAF1B
NCBI Gene:9014 TAF1B
OMIM:604904 TAF1B
UCSC:Q53T94 TAF1B
Reference Transcript
RefSeq:NM_001318976.1 TAF1B
RefSeq:NM_005680.2 TAF1B
Other Identifiers
0003130687
11734845_at
11734846_x_at
11749175_a_at
16876950
214690_PM_at
214690_at
216941_PM_s_at
216941_s_at
2469096
2469099
2469104
2469105
2469108
2469113
2469115
2469116
2469119
2469120
2469126
2469127
2469128
2469129
2469137
2469139
2469140
2469146
2469147
34497_at
71653_r_at
8040173
9014
A_14_P133556
A_23_P165891
GE80287
GO:0001164
GO:0001188
GO:0003677
GO:0005515
GO:0005622
GO:0005634
GO:0005654
GO:0005668
GO:0005730
GO:0006351
GO:0006360
GO:0017025
GO:0032991
GO:0042790
GO:0043226
GO:0046872
GO:0065003
GO:0070860
HMNXSV003054761
Hs.121044.0.S1_3p_a_at
Hs.121044.1.S1_3p_at
ILMN_1667977
ILMN_2143487
L39061_at
PH_hs_0006706
TC02000053.hg
Participates
as a component of
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
TAF1B [nucleoplasm]
Inferred To
Ac-TAF1B [nucleoplasm]
(Bos taurus)
Ac-TAF1B [nucleoplasm]
(Caenorhabditis elegans)
Ac-TAF1B [nucleoplasm]
(Canis familiaris)
Ac-TAF1B [nucleoplasm]
(Danio rerio)
Ac-TAF1B [nucleoplasm]
(Dictyostelium discoideum)
Ac-TAF1B [nucleoplasm]
(Drosophila melanogaster)
Ac-TAF1B [nucleoplasm]
(Gallus gallus)
Ac-TAF1B [nucleoplasm]
(Mus musculus)
Ac-TAF1B [nucleoplasm]
(Rattus norvegicus)
Ac-TAF1B [nucleoplasm]
(Saccharomyces cerevisiae)
Ac-TAF1B [nucleoplasm]
(Schizosaccharomyces pombe)
Ac-TAF1B [nucleoplasm]
(Xenopus tropicalis)
TAF1B [nucleoplasm]
(Sus scrofa)
Modified Residues
Name
N6-acetyl-L-lysine at unknown position
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_001305905.1
,
NP_005671.2
OpenTargets
ENSG00000115750
GeneCards
Q53T94
HPA
ENSG00000115750-TAF1B
Ensembl
ENST00000263663
,
ENSP00000263663
,
ENSG00000115750
PRO
Q53T94
Pharos - Targets
Q53T94
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20226 TBP
1
TBP [nucleoplasm]
(R-HSA-83718)
0.688
4
UniProt:P27797 CALR
6
CALR [integral component of lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
0.556
3
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:P49748 ACADVL
1
ACADVL [mitochondrial matrix]
(R-HSA-49495)
0.556
3
UniProt:Q01105 SET
1
SET [nucleoplasm]
(R-HSA-451201)
0.524
3
© 2023
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text