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Ac-TAF1B [nucleoplasm]
Stable Identifier
R-HSA-5138530
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
acetylated TAF(1)68
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
Epigenetic regulation of gene expression (Homo sapiens)
Negative epigenetic regulation of rRNA expression (Homo sapiens)
NoRC negatively regulates rRNA expression (Homo sapiens)
Transcription of intergenic spacer of the rRNA gene (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
SIRT1 negatively regulates rRNA expression (Homo sapiens)
SIRT1 deacetylates TAF1B in SL1 complex (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription (Homo sapiens)
RNA Polymerase I Promoter Clearance (Homo sapiens)
RNA Polymerase I Promoter Escape (Homo sapiens)
Elongation of pre-rRNA transcript (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Loss of Rrn3 from RNA Polymerase I promoter escape complex (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation (Homo sapiens)
Acetylation of SL1 (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Recruitment of Acetylated SL1 to phosUBF-1:rDNA Promoter (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Recruitment of Active RNA Polymerase I to SL1:phos.UBF-1:rDNA Promoter (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Initiation complex [nucleoplasm] (Homo sapiens)
Acetylayed SL1:PhosUBF-1:rDNA promoter [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I Transcription Termination (Homo sapiens)
Dissociation of PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
PTRF Binds the Polymerase I Transcription Complex/Nascent Pre rRNA Complex paused at the TTF-I:Sal Box (Homo sapiens)
PTRF:Polymerase I/Nascent Pre rRNA Complex:TTF-I:Sal Box [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
Polymerase I Transcription Complex/Nascent Pre rRNA Complex pauses at the TTF-I:Sal Box (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
RNA Polymerase I:rRNATranscript:TTF-1:Sal Box Complex [nucleoplasm] (Homo sapiens)
RNA Polymerase I promoter escape complex [nucleoplasm] (Homo sapiens)
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Ac-TAF1B [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q53T94 TAF1B
Gene Names
TAF1B
Chain
chain:1-588
Reference Genes
BioGPS Gene:9014 TAF1B
COSMIC (genes):TAF1B TAF1B
CTD Gene:9014 TAF1B
dbSNP Gene:9014 TAF1B
ENSEMBL:ENSG00000115750 TAF1B
HGNC:11533 TAF1B
KEGG:hsa:9014 TAF1B
Monarch:9014 TAF1B
NCBI Gene:9014 TAF1B
OMIM:604904 TAF1B
UCSC:Q53T94 TAF1B
Reference Transcript
RefSeq:NM_005680.2 TAF1B
RefSeq:NM_001318976.1 TAF1B
RefSeq:NM_005680.3 TAF1B
Other Identifiers
11734845_at
11734846_x_at
11749175_a_at
16876950
214690_PM_at
214690_at
216941_PM_s_at
216941_s_at
2469095
2469096
2469097
2469098
2469099
2469100
2469101
2469102
2469104
2469105
2469106
2469107
2469108
2469113
2469114
2469115
2469116
2469119
2469120
2469126
2469127
2469128
2469129
2469130
2469131
2469137
2469139
2469140
2469146
2469147
34497_at
55779_at
71653_r_at
8040173
9014
A_14_P133556
A_23_P165891
A_33_P3392802
A_33_P3392807
GE80287
GO:0000120
GO:0001164
GO:0001188
GO:0003677
GO:0005515
GO:0005634
GO:0005654
GO:0005668
GO:0005730
GO:0006351
GO:0006360
GO:0008270
GO:0017025
GO:0042790
GO:0043226
GO:0065003
GO:0070860
HMNXSV003024648
HMNXSV003028692
HMNXSV003054761
Hs.121044.0.S1_3p_a_at
Hs.121044.1.S1_3p_at
ILMN_1667977
ILMN_2143487
L39061_at
PH_hs_0006706
TC02000053.hg
Participates
as a component of
Acetylated SL1 [nucleoplasm] (Homo sapiens)
Other forms of this molecule
TAF1B [nucleoplasm]
Inferred To
Taf1b [nucleoplasm]
(Mus musculus)
Taf1b [nucleoplasm]
(Rattus norvegicus)
RRN7 [nucleoplasm]
(Saccharomyces cerevisiae)
taf1b [nucleoplasm]
(Xenopus tropicalis)
Ac-TAF1B [nucleoplasm]
(Caenorhabditis elegans)
Ac-TAF1B [nucleoplasm]
(Dictyostelium discoideum)
TAF1B [nucleoplasm]
(Bos taurus)
TAF1B [nucleoplasm]
(Canis familiaris)
TAF1B [nucleoplasm]
(Drosophila melanogaster)
TAF1B [nucleoplasm]
(Gallus gallus)
TAF1B [nucleoplasm]
(Sus scrofa)
rrn7 [nucleoplasm]
(Schizosaccharomyces pombe)
Modified Residues
Name
N6-acetyl-L-lysine at unknown position
PsiMod Name
N6-acetyl-L-lysine [MOD:00064]
PsiMod Definition
A protein modification that effectively converts an L-lysine residue to N6-acetyl-L-lysine.
Cross References
RefSeq
NP_001305905.1
,
NP_005671.3
,
NP_005671.2
ENSEMBL
ENST00000263663
,
ENSP00000263663
,
ENSG00000115750
OpenTargets
ENSG00000115750
GeneCards
TAF1B
HPA
ENSG00000115750-TAF1B
PRO
Q53T94
Pharos - Targets
Q53T94
Interactors (9)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P20226 TBP
1
TBP [nucleoplasm]
(R-HSA-83718)
0.757
5
UniProt:Q15573 TAF1A
1
TAF1A [nucleoplasm]
(R-HSA-73689)
0.669
4
UniProt:Q15572 TAF1C
1
TAF1C [nucleoplasm]
(R-HSA-73687)
0.669
5
UniProt:P27797 CALR
6
CALR [lumenal side of endoplasmic reticulum membrane]
(R-HSA-985502)
CALR [extracellular region]
(R-HSA-2197641)
CALR [endocytic vesicle lumen]
(R-HSA-2239448)
CALR [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-HSA-8863866)
CALR [phagocytic vesicle membrane]
(R-HSA-1236879)
CALR [endoplasmic reticulum lumen]
(R-HSA-195905)
0.556
3
UniProt:P49748 ACADVL
1
ACADVL [mitochondrial matrix]
(R-HSA-49495)
0.556
3
UniProt:Q6FHY5 Q6FHY5
0.556
3
UniProt:Q9H5J8 TAF1D
1
TAF1D [nucleoplasm]
(R-HSA-5138533)
0.527
3
UniProt:O75607 NPM3
0.527
3
UniProt:Q01105 SET
1
SET [nucleoplasm]
(R-HSA-451201)
0.524
3
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