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PPARD [nucleoplasm]
Stable Identifier
R-HSA-446176
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
nucleoplasm
Synonyms
Peroxisome proliferator-activated receptor delta, PPARD_HUMAN
Icon
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Nuclear Receptor transcription pathway (Homo sapiens)
Formation of NR-MED1 Coactivator Complex (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
NR-MED1 Coactivator Complex [nucleoplasm] (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
Formation of NR-NCOR Corepressor Complex (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
NR-NCOR CoRepressor Complex [nucleoplasm] (Homo sapiens)
NR [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine shuttle (Homo sapiens)
CPT1A transfers PALM to CAR (Homo sapiens)
RXRA:PPARD:atRA [nucleoplasm] (Homo sapiens)
RXRA:PPARD [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
FABP5 dissociates from RXRA:PPARD:atRA (Homo sapiens)
RXRA:PPARD:atRA [nucleoplasm] (Homo sapiens)
RXRA:PPARD [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Homo sapiens)
RXRA:PPARD [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
RXRA:PPARD binds FABP5:atRA (Homo sapiens)
RXRA:PPARD [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Homo sapiens)
RXRA:PPARD [nucleoplasm] (Homo sapiens)
PPARD [nucleoplasm] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q03181 PPARD
Gene Names
PPARD, NR1C2, PPARB
Chain
chain:1-441
Reference Genes
BioGPS Gene:5467 PPARD
COSMIC (genes):PPARD PPARD
CTD Gene:5467 PPARD
dbSNP Gene:5467 PPARD
ENSEMBL:ENSG00000112033 PPARD
ENSEMBL_homo_sapiens_GENE:ENSG00000112033.14 PPARD
HGNC:9235 PPARD
KEGG Gene (Homo sapiens):5467 PPARD
Monarch:5467 PPARD
NCBI Gene:5467 PPARD
OMIM:600409 PPARD
UCSC:Q03181 PPARD
Reference Transcript
RefSeq:NM_177435.2 PPARD
RefSeq:XM_017010974.1 PPARD
RefSeq:NM_006238.4 PPARD
RefSeq:XM_017010973.1 PPARD
RefSeq:XM_017010972.1 PPARD
RefSeq:XM_011514707.1 PPARD
RefSeq:XM_006715123.1 PPARD
RefSeq:NM_001171820.1 PPARD
RefSeq:XM_017010971.1 PPARD
RefSeq:NM_001171819.1 PPARD
RefSeq:XM_011514710.1 PPARD
RefSeq:XM_006715120.1 PPARD
RefSeq:NM_001171818.1 PPARD
RefSeq:XM_005249193.1 PPARD
RefSeq:XM_011514709.1 PPARD
Other Identifiers
11725170_a_at
11725171_at
11735395_at
17007810
208044_3p_s_at
208044_PM_s_at
208044_s_at
210636_3p_at
210636_PM_at
210636_at
2904598
2904599
2904600
2904604
2904620
2904625
2904626
2904627
2904634
2904637
2904640
2904642
2904643
2904644
2904645
2904646
2904647
2904648
2904649
2904650
2904652
37152_PM_at
37152_at
5467
8118945
91954_s_at
91956_r_at
A_23_P214681
A_24_P252130
GE56066
GE592698
GO:0000122
GO:0000785
GO:0000978
GO:0000981
GO:0001223
GO:0001227
GO:0001890
GO:0003677
GO:0003700
GO:0003707
GO:0004879
GO:0005515
GO:0005634
GO:0005654
GO:0005694
GO:0005975
GO:0006006
GO:0006091
GO:0006351
GO:0006355
GO:0006357
GO:0006629
GO:0006631
GO:0006635
GO:0006915
GO:0006954
GO:0007154
GO:0007155
GO:0007566
GO:0008203
GO:0008270
GO:0008283
GO:0008289
GO:0008366
GO:0009062
GO:0009755
GO:0010628
GO:0010887
GO:0012501
GO:0014842
GO:0015908
GO:0022414
GO:0023052
GO:0030154
GO:0030522
GO:0031589
GO:0031669
GO:0042060
GO:0042127
GO:0043226
GO:0043401
GO:0043415
GO:0043491
GO:0043565
GO:0043616
GO:0045598
GO:0045600
GO:0045662
GO:0045892
GO:0045893
GO:0045923
GO:0045944
GO:0046697
GO:0046872
GO:0048856
GO:0048870
GO:0050673
GO:0050678
GO:0050680
GO:0050728
GO:0051546
GO:0051716
GO:0051897
GO:0055085
GO:0060089
GO:0060612
GO:0070341
GO:0070346
GO:0070539
GO:0071456
GO:0097009
GO:0097190
GO:0140110
GO:0140297
GO:1902894
GO:1904659
GO:1990837
GO:2000288
HMNXSV003033220
HMNXSV003041279
ILMN_1674282
ILMN_1779794
ILMN_1811973
L07592_at
PH_hs_0005922
TC06000514.hg
TC06002752.hg
g12803754_3p_at
g12803754_3p_x_at
g5453939_3p_a_at
g5453939_3p_s_at
g5453939_3p_x_at
Participates
as a member of
NR [nucleoplasm] (Homo sapiens)
as a component of
RXRA:PPARD [nucleoplasm] (Homo sapiens)
Inferred To
ppardb [nucleoplasm]
(Danio rerio)
Homologues of PPARD [nucleoplasm]
(Caenorhabditis elegans)
nhr-2 [nucleoplasm]
(Caenorhabditis elegans)
Eip75B [nucleoplasm]
(Drosophila melanogaster)
Ppard [nucleoplasm]
(Mus musculus)
nhr-7 [nucleoplasm]
(Caenorhabditis elegans)
nhr-85 [nucleoplasm]
(Caenorhabditis elegans)
PPARD [nucleoplasm]
(Bos taurus)
PPARD [nucleoplasm]
(Canis familiaris)
PPARD [nucleoplasm]
(Gallus gallus)
PPARD [nucleoplasm]
(Rattus norvegicus)
PPARD [nucleoplasm]
(Sus scrofa)
ppard [nucleoplasm]
(Xenopus tropicalis)
sex-1 [nucleoplasm]
(Caenorhabditis elegans)
unc-55 [nucleoplasm]
(Caenorhabditis elegans)
Cross References
RefSeq
XP_005249250.1
,
NP_006229.1
,
XP_006715186.1
,
XP_011513011.1
,
NP_001165290.1
,
NP_001165289.1
,
XP_011513009.1
,
XP_016866460.1
,
NP_001165291.1
,
XP_011513012.1
,
XP_016866463.1
,
XP_006715183.1
,
NP_803184.1
,
XP_016866461.1
,
XP_016866462.1
ZINC - World Drugs
PPARD_HUMAN
Guide to Pharmacology - Targets
594
OpenTargets
ENSG00000112033
ZINC - FDA approved
PPARD_HUMAN
ZINC - Substances
PPARD_HUMAN
ZINC target
Q03181
ZINC - Biogenic
PPARD_HUMAN
PRO
Q03181
PDB
5U3Y
,
5U44
,
7W0G
,
5U43
,
8HF8
,
3GWX
,
2ENV
,
5U3R
,
8HUO
,
5U3W
,
2J14
,
2B50
,
6A6P
,
7VWE
,
2ZNQ
,
3D5F
,
5U3Q
,
2AWH
,
3ET2
,
5ZXI
,
2XYX
,
5U3V
,
7VWF
,
2GWX
,
5U46
,
7WGN
,
5U40
,
2ZNP
,
2XYW
,
3OZ0
,
2Q5G
,
5U3T
,
7VWH
,
3GZ9
,
1GWX
,
8HUL
,
3DY6
,
3SP9
,
5U3S
,
5U3X
,
2XYJ
,
3TKM
,
5Y7X
,
5U42
,
3PEQ
,
1Y0S
,
7WGL
,
5U41
,
7F80
,
5U3U
,
5U3Z
,
5XMX
,
7VWG
,
2BAW
,
5U45
ZINC - Investigational
PPARD_HUMAN
ZINC - Metabolites
PPARD_HUMAN
HPA
ENSG00000112033-PPARD
GeneCards
Q03181
Ensembl
ENST00000311565
,
ENST00000418635
,
ENSP00000337063
,
ENSG00000112033
,
ENSP00000413314
,
ENST00000448077
,
ENSP00000353916
,
ENSP00000414372
,
ENSP00000310928
,
ENST00000337400
,
ENST00000360694
Pharos - Targets
Q03181
ZINC - Predictions - Purchasable
PPARD_HUMAN
HMDB Protein
HMDBP02359
Interactors (1)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:O60341 KDM1A
1
KDM1A [nucleoplasm]
(R-HSA-996769)
0.508
2
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