Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
GRIN2A [plasma membrane]
Stable Identifier
R-HSA-419556
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Glutamate (NMDA) receptor subunit epsilon-1, NMDE1_HUMAN
Locations in the PathwayBrowser
Expand all
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by MECP2 (Homo sapiens)
MECP2 regulates neuronal receptors and channels (Homo sapiens)
GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Neuronal System (Homo sapiens)
Protein-protein interactions at synapses (Homo sapiens)
Neurexins and neuroligins (Homo sapiens)
BEGAIN binds DLG2,DLG3,DLG4 (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:PSD-95:BEGAIN [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 binds SPAR (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR binds PDLIM5 (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR:PDLIM5 [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4:SPAR [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDAR binds PSD-95 subfamily members (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDA receptor complex:DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Synaptic adhesion-like molecules (Homo sapiens)
PSD-95 binds NMDA receptor (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
SALM1 binds NMDA receptor (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
SALM1:NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDAR:PSD-95 [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
SALM2 associate with AMPA and NMDA receptors (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
SALM2:AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
AMPA, NMDA receptors [plasma membrane] (Homo sapiens)
NMDA receptor complex [plasma membrane] (Homo sapiens)
NMDA receptor [plasma membrane] (Homo sapiens)
NR2 subunits [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Assembly and cell surface presentation of NMDA receptors (Homo sapiens)
CaMKII and LRRC7 bind to NMDA receptors at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GluN1 (GRIN1) binds to ACTN2 at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GluN1 (GRIN1) binds to NEFL at postsynaptic density (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors bind to postsynaptic density proteins (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GluN3A (GRIN3A), GluN3B (GRIN3B) NMDA receptors traffic to the plasma membrane (Homo sapiens)
GRIN1:GRIN3 di-heteromers,(GRIN1:GRIN2:GRIN3 tri-heteromers) [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN3A tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN3B tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Negative regulation of NMDA receptor-mediated neuronal transmission (Homo sapiens)
CALM1:4xCa2+ binds GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors and displaces ACTN2 (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:CALM1:4xCa2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:LRRC7:CaMKII dodecamer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Post NMDA receptor activation events (Homo sapiens)
Long-term potentiation (Homo sapiens)
SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Ca2+ influx into the post-synaptic cell (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Glycine and glutamate ligands bind GRIN1:GRIN2 NMDA receptor (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Mg2+ binds GRIN1:GRIN2 NMDA receptors (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Unblocking of GRIN1:GRIN2 NMDA receptors (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins:Mg2+ [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Homo sapiens)
GRIN1:GRIN2 NMDA receptors [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN2A [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q12879 GRIN2A
Gene Names
GRIN2A, NMDAR2A
Chain
signal peptide:1-22, chain:23-1464
Reference Genes
BioGPS Gene:2903 GRIN2A
COSMIC (genes):GRIN2A GRIN2A
CTD Gene:2903 GRIN2A
dbSNP Gene:2903 GRIN2A
ENSEMBL:ENSG00000183454 GRIN2A
ENSEMBL_homo_sapiens_GENE:ENSG00000183454.18 GRIN2A
HGNC:4585 GRIN2A
KEGG Gene (Homo sapiens):2903 GRIN2A
Monarch:2903 GRIN2A
NCBI Gene:2903 GRIN2A
OMIM:138253 GRIN2A
UCSC:Q12879 GRIN2A
Reference Transcript
RefSeq:NM_001134408.2 GRIN2A
RefSeq:NM_000833.4 GRIN2A
RefSeq:XM_011522461.2 GRIN2A
RefSeq:NM_001134407.2 GRIN2A
Other Identifiers
11726959_a_at
11726960_a_at
11740941_a_at
16823799
206534_PM_at
206534_at
231384_PM_at
231384_at
242286_PM_at
242286_at
2903
3679802
3679804
3679806
3679808
3679810
3679811
3679813
3679814
3679815
3679816
3679817
3679818
3679826
3679830
3679832
3679833
3679834
3679835
3679838
3679843
3679848
3679874
3679877
3679878
3679879
38236_at
46626_at
54354_at
7999364
A_23_P100278
A_24_P358628
A_24_P381844
A_32_P169114
A_33_P3334895
GE484642
GE58236
GE796610
GO:0001540
GO:0001964
GO:0001975
GO:0004970
GO:0004972
GO:0005215
GO:0005216
GO:0005261
GO:0005262
GO:0005515
GO:0005783
GO:0005789
GO:0005886
GO:0006811
GO:0006816
GO:0007215
GO:0007268
GO:0007420
GO:0007611
GO:0007612
GO:0007613
GO:0008021
GO:0008270
GO:0008542
GO:0009410
GO:0009611
GO:0009986
GO:0012501
GO:0014069
GO:0015276
GO:0016020
GO:0017146
GO:0019233
GO:0019722
GO:0022008
GO:0022849
GO:0022890
GO:0023052
GO:0030154
GO:0030163
GO:0030431
GO:0030659
GO:0031090
GO:0031410
GO:0033058
GO:0034220
GO:0035235
GO:0035249
GO:0038023
GO:0040011
GO:0042177
GO:0042391
GO:0042417
GO:0042428
GO:0042734
GO:0042995
GO:0043005
GO:0043065
GO:0043197
GO:0043226
GO:0045202
GO:0045211
GO:0045471
GO:0046872
GO:0048167
GO:0048168
GO:0048856
GO:0050804
GO:0050877
GO:0051604
GO:0051968
GO:0055085
GO:0060078
GO:0060079
GO:0060089
GO:0060291
GO:0070588
GO:0097060
GO:0097202
GO:0097553
GO:0098655
GO:0098794
GO:0098839
GO:0098976
GO:0098978
GO:1903539
GO:1904062
GO:1904315
GO:2000463
HMNXSV003053973
Hs.46550.0.A1_3p_at
Hs.6818.0.A1_3p_at
ILMN_1798104
ILMN_1886395
ILMN_1895745
ILMN_1901382
PH_hs_0022379
PH_hs_0038488
TC16000854.hg
TC16001763.hg
U09002_at
g6006002_3p_at
Participates
as an output of
GRIN2A gene expression is stimulated by MECP2 (Homo sapiens)
as a member of
NR2 subunits [plasma membrane] (Homo sapiens)
as a component of
GRIN1:GRIN2A:GRIN3A tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN3B tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Homo sapiens)
GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Homo sapiens)
Other forms of this molecule
GRIN2A [endoplasmic reticulum membrane]
p-Y-GRIN2A [plasma membrane]
Inferred To
Nmdar2 [plasma membrane]
(Drosophila melanogaster)
grin2a [plasma membrane]
(Xenopus tropicalis)
Grin2a [plasma membrane]
(Mus musculus)
Grin2a [plasma membrane]
(Rattus norvegicus)
nmr-2 [plasma membrane]
(Caenorhabditis elegans)
GRIN2A [plasma membrane]
(Canis familiaris)
GRIN2A [plasma membrane]
(Gallus gallus)
GRIN2A [plasma membrane]
(Sus scrofa)
Cross References
RefSeq
NP_001127879.1
,
XP_011520763.1
,
NP_000824.1
,
NP_001127880.1
Guide to Pharmacology - Targets
456
OpenTargets
ENSG00000183454
ZINC - Substances
NMDE1_HUMAN
ZINC target
Q12879
PRO
Q12879
PDB
5I2N
,
5KDT
,
6IRG
,
5H8N
,
7EOS
,
5I2K
,
8E99
,
7EU7
,
5H8H
,
5TPA
,
7EOR
,
6IRF
,
5H8Q
,
5H8F
,
6IRA
,
3NFL
,
5KCJ
,
7EOQ
,
7EOU
,
5TP9
,
7EOT
,
6IRH
GeneCards
Q12879
HPA
ENSG00000183454-GRIN2A
Ensembl
ENSP00000379818
,
ENST00000396573
,
ENST00000330684
,
ENSP00000332549
,
ENSP00000454998
,
ENSG00000183454
,
ENST00000562109
Pharos - Targets
Q12879
ZINC - Predictions - Purchasable
NMDE1_HUMAN
Orphanet
20706
HMDB Protein
HMDBP01642
Interactors (4)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P78352 DLG4
3
DLG4 [cytosol]
(R-HSA-6794267)
DLG4 [endocytic vesicle membrane]
(R-HSA-416847)
DLG4 [plasma membrane]
(R-HSA-202135)
0.75
6
UniProt:Q62936
2
Dlg3 [cytosol]
(R-RNO-6794232)
Dlg3 [plasma membrane]
(R-RNO-443609)
0.558
5
UniProt:P31016 Dlg4
3
Dlg4 [endocytic vesicle membrane]
(R-RNO-416847)
Dlg4 [cytosol]
(R-RNO-6794248)
Dlg4 [plasma membrane]
(R-RNO-9612601)
0.558
2
UniProt:Q9WU22
1
PTPN4 [cytosol]
(R-MMU-8877173)
0.524
5
© 2024
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text