Reactome | GRIN2A [plasma membrane]

GRIN2A [plasma membrane]

Stable Identifier

R-SSC-419556

Type

Protein [EntityWithAccessionedSequence]

Species

Sus scrofa

Compartment

plasma membrane

Synonyms

GRIN2A, A0A287BN68

Locations in the PathwayBrowser

Expand all

Neuronal System (Sus scrofa)

- Protein-protein interactions at synapses (Sus scrofa)
  - Synaptic adhesion-like molecules (Sus scrofa)
    - PSD-95 binds NMDA receptor (Sus scrofa)
      - NMDA receptor complex [plasma membrane] (Sus scrofa)
        
        NMDA receptor [plasma membrane] (Sus scrofa)
        
        NR2 subunits [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
      - NMDAR:PSD-95 [plasma membrane] (Sus scrofa)
        
        NMDA receptor complex [plasma membrane] (Sus scrofa)
        
        NMDA receptor [plasma membrane] (Sus scrofa)
        
        NR2 subunits [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
    - SALM1 binds NMDA receptor (Sus scrofa)
      - NMDAR:PSD-95 [plasma membrane] (Sus scrofa)
        
        NMDA receptor complex [plasma membrane] (Sus scrofa)
        
        NMDA receptor [plasma membrane] (Sus scrofa)
        
        NR2 subunits [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
      - SALM1:NMDAR:PSD-95 [plasma membrane] (Sus scrofa)
        
        NMDAR:PSD-95 [plasma membrane] (Sus scrofa)
        
        NMDA receptor complex [plasma membrane] (Sus scrofa)
        
        NMDA receptor [plasma membrane] (Sus scrofa)
        
        NR2 subunits [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
- Transmission across Chemical Synapses (Sus scrofa)
  - Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
    - Activation of NMDA receptors and postsynaptic events (Sus scrofa)
      - Assembly and cell surface presentation of NMDA receptors (Sus scrofa)
        
        GluN1:GluN2 (GRIN1:GRIN2) NMDA receptors traffic to the plasma membrane (Sus scrofa)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
      - Unblocking of NMDA receptors, glutamate binding and activation (Sus scrofa)
        
        Ca2+ influx into the post-synaptic cell (Sus scrofa)
        
        Gly,D-Ser:L-Glu:GRIN1:GRIN2 NMDA receptors [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:PSD proteins [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL:ACTN2 [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4:NEFL [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors:DLG4:DLG1,DLG2,DLG3,DLG4 [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2 NMDA receptors [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A,C,D di-heteromers,GRIN1:GRIN2 tri-heteromers [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A di-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A:GRIN2C tri-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)
        
        GRIN1:GRIN2A:GRIN2D tri-heterotetramer [plasma membrane] (Sus scrofa)
        
        GRIN2A [plasma membrane] (Sus scrofa)

External Reference Information

External Reference

UniProt:A0A287BN68

Gene Names

GRIN2A

Reference Genes

ENSEMBL:ENSSSCG00000031290.3

Other Identifiers

100736832

GO:0001964

GO:0001975

GO:0004970

GO:0004972

GO:0005215

GO:0005216

GO:0005261

GO:0005262

GO:0005783

GO:0005886

GO:0006811

GO:0006816

GO:0007268

GO:0007611

GO:0007612

GO:0007613

GO:0008021

GO:0008542

GO:0009410

GO:0009611

GO:0009986

GO:0012501

GO:0014069

GO:0015276

GO:0016020

GO:0017146

GO:0019233

GO:0019722

GO:0022008

GO:0022849

GO:0022890

GO:0023052

GO:0030154

GO:0030163

GO:0030431

GO:0031410

GO:0033058

GO:0034220

GO:0035235

GO:0035249

GO:0038023

GO:0040011

GO:0042177

GO:0042391

GO:0042417

GO:0042428

GO:0042734

GO:0043005

GO:0043065

GO:0043226

GO:0045202

GO:0045211

GO:0045471

GO:0048167

GO:0048856

GO:0050804

GO:0050877

GO:0055085

GO:0060078

GO:0060079

GO:0060089

GO:0060291

GO:0097060

GO:0097553

GO:0098794

GO:0098839

GO:0098978

GO:1903539

GO:1904315

Ssc.18403.1.A1_at

Participates

as a member of

NR2 subunits [plasma membrane] (Sus scrofa)

as a component of

Other forms of this molecule

GRIN2A [endoplasmic reticulum membrane]

Inferred From

GRIN2A [plasma membrane] (Homo sapiens)

Cross References

OpenTargets

ENSG00000183454

Ensembl

ENSSSCT00000065791, ENSSSCG00000031290, ENSSSCP00000057526

VGNC

88683

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