Reactome | OCLN(321-522) [plasma membrane]

OCLN(321-522) [plasma membrane]

Stable Identifier

R-HSA-351873

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Occludin fragment (321-522)

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q16625 OCLN

Gene Names

OCLN

Chain

chain:1-522

Reference Genes

BioGPS Gene:100506658 OCLN

COSMIC (genes):OCLN OCLN

CTD Gene:100506658 OCLN

dbSNP Gene:100506658 OCLN

ENSEMBL:ENSG00000197822 OCLN

HGNC:8104 OCLN

KEGG:hsa:100506658 OCLN

Monarch:100506658 OCLN

NCBI Gene:100506658 OCLN

OMIM:602876 OCLN

UCSC:Q16625 OCLN

Reference Transcript

Other Identifiers

100506658

11728484_s_at

11747434_a_at

11747435_s_at

16985704

209925_PM_at

209925_at

227492_PM_at

227492_at

231022_PM_at

231022_at

235937_PM_at

235937_at

2813591

2813592

2813594

2813595

2813596

2813599

2813600

2813601

2813602

2813603

2813604

2813605

2813606

2813607

2813609

2813611

2813615

2813616

2813617

2813618

2813619

2813622

2813623

2813624

2813625

2813626

2813627

2813628

2813629

2813630

2813632

2813633

2813634

2813635

2813636

2813637

2813638

2813639

2813640

2813641

2813643

2813644

2813645

2813646

2813651

2813653

2861221

2861222

2861223

2861243

2861244

2861245

2861246

2861247

2861248

2861249

2861250

2861251

2861252

2861254

2861256

2861723

2861724

2861727

2861728

2861729

2861730

2861731

2861732

2861733

2861734

2861735

2861736

2861737

2861738

2861739

2861740

38524_at

43530_at

8105908

81183_at

82255_at

A_23_P92672

A_24_P102053

GE79065

GE88248

GO:0001933

GO:0003013

GO:0005515

GO:0005765

GO:0005886

GO:0005911

GO:0005923

GO:0010592

GO:0010628

GO:0010629

GO:0010827

GO:0016020

GO:0016324

GO:0016327

GO:0019904

GO:0030054

GO:0030139

GO:0031116

GO:0031252

GO:0031410

GO:0032991

GO:0034330

GO:0035633

GO:0043226

GO:0045216

GO:0046326

GO:0065003

GO:0070160

GO:0070830

GO:0090303

GO:0120193

GO:1902463

GO:1905605

HMNXSV003007992

HMNXSV003030282

HMNXSV003058299

Hs.134586.0.A1_3p_at

Hs.155965.0.A1_3p_at

Hs.171952.1.S1_3p_at

ILMN_1651916

ILMN_1697504

ILMN_1724149

ILMN_1731729

PH_hs_0027277

TC05000304.hg

TC05001458.hg

TC05003057.hg

U19251_s_at

g1322281_3p_at

Participates

as an output of

Caspase-mediated cleavage of occludin (Homo sapiens)

Other forms of this molecule

OCLN [plasma membrane]

OCLN(1-320) [plasma membrane]

OCLN [cell junction]

Inferred To

ell-1 [plasma membrane] (Caenorhabditis elegans)

ocln [plasma membrane] (Xenopus tropicalis)

oclna [plasma membrane] (Danio rerio)

Ocln [plasma membrane] (Mus musculus)

Ocln [plasma membrane] (Rattus norvegicus)

Ell [plasma membrane] (Drosophila melanogaster)

OCLN [plasma membrane] (Bos taurus)

OCLN [plasma membrane] (Canis familiaris)

OCLN [plasma membrane] (Sus scrofa)

Cross References

RefSeq

XP_016864403.1, NP_001192184.1, NP_001192183.1, NP_002529.1, XP_016864402.1

OpenTargets

ENSG00000197822

ENSEMBL

ENST00000538151, ENSP00000379719, ENSP00000505541, ENSP00000506162, ENSP00000506305, ENST00000680784, ENST00000680027, ENST00000681586, ENST00000681041, ENSP00000505426, ENST00000680496, ENST00000355237, ENSP00000504966, ENSP00000445940, ENST00000396442, ENSP00000347379

HPA

ENSG00000197822-OCLN

PRO

Q16625

Pharos - Targets

Q16625

GlyGen

Q16625

Orphanet

OCLN

PDB

3G7C, 1XAW, 1WPA

Interactors (17)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P49674 CSNK1E	2	CSNK1E [cytosol] (R-HSA-205877) CSNK1E [nucleoplasm] (R-HSA-421306)	0.835	10
UniProt:Q8N205 SYNE4			0.666	4
UniProt:P19404 NDUFV2	1	NDUFV2 [mitochondrial inner membrane] (R-HSA-163939)	0.556	3
UniProt:Q9BXN2 CLEC7A	2	CLEC7A [plasma membrane] (R-HSA-2130683) p-Y15-CLEC7A [plasma membrane] (R-HSA-5607641)	0.556	3
UniProt:P50570-2 DNM2			0.556	3
UniProt:Q8TED1 GPX8	1	GPX8 [endoplasmic reticulum lumen] (R-HSA-3341303)	0.556	3
UniProt:P32971 TNFSF8	1	TNFSF8 [plasma membrane] (R-HSA-5667148)	0.527	3
UniProt:Q9Y375 NDUFAF1	1	NDUFAF1 [mitochondrial inner membrane] (R-HSA-5689050)	0.527	3
UniProt:Q8N7X8 SIGL1			0.527	2
UniProt:Q96PC5 MIA2	1	MIA2 [endoplasmic reticulum membrane] (R-HSA-9637821)	0.527	2
UniProt:Q9HCU5 PREB	1	PREB [endoplasmic reticulum membrane] (R-HSA-203984)	0.527	4
UniProt:P0C0L4 C4A	11	dNQ-C4A(757-1446) [extracellular region] (R-HSA-2855053) C4A(1454-1744) [extracellular region] (R-HSA-166731) C4A(20-675) [extracellular region] (R-HSA-166734) S-(L-isoglutamyl)-L-cysteine-C4A(757-1446) [extracellular region] (R-HSA-166736) C4 alpha [extracellular region] (R-HSA-166729) C4A-derived C4a [extracellular region] (R-HSA-166737) C4A(956-1336) [plasma membrane] (R-HSA-981501) C4A alpha3 [extracellular region] (R-HSA-981503) C4A alpha4 fragment [extracellular region] (R-HSA-981506) C4A [endoplasmic reticulum lumen] (R-HSA-8956717) p-C4A [endoplasmic reticulum lumen] (R-HSA-8956932)	0.527	2
UniProt:Q9H6X2 ANTXR1			0.527	2
UniProt:P18827 SDC1	20	HS(4)-SDC1 [plasma membrane] (R-HSA-2076693) HS(6)-SDC1 [plasma membrane] (R-HSA-2076652) HS(2)-SDC1 [plasma membrane] (R-HSA-2076666) HS(1)-SDC1 [plasma membrane] (R-HSA-2076672) HS(3)-SDC1 [plasma membrane] (R-HSA-2076691) HS(5)-SDC1 [plasma membrane] (R-HSA-2076626) SDC1 [plasma membrane] (R-HSA-174758) XylS-SDC1 [Golgi lumen] (R-HSA-2064146) Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064148) SDC1 [Golgi lumen] (R-HSA-2054105) Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064247) GlcA-Gal-Gal-Xyl-SDC1 [Golgi lumen] (R-HSA-2064082) HS(3)-SDC1 [Golgi lumen] (R-HSA-2076444) HS(4)-SDC1 [Golgi lumen] (R-HSA-2076593) HS(2)-SDC1 [Golgi lumen] (R-HSA-2076309) HS(1)-SDC1 [Golgi lumen] (R-HSA-2076321) Heparan(4)-SDC1 [Golgi lumen] (R-HSA-2076339) Heparan(3)-SDC1 [Golgi lumen] (R-HSA-2076314) Heparan(2)-SDC1 [Golgi lumen] (R-HSA-2076558) Heparan(1)-SDC1 [Golgi lumen] (R-HSA-2076349)	0.527	2
UniProt:P55083 MFAP4	1	MFAP4 [extracellular region] (R-HSA-2161384)	0.527	3
UniProt:Q3MIR4 CC50B			0.527	2
UniProt:O75165 DNAJC13	3	DNAJC13 [azurophil granule membrane] (R-HSA-6799140) DNAJC13 [plasma membrane] (R-HSA-6806255) DNAJC13 [secretory granule membrane] (R-HSA-6800951)	0.527	3

Cite Us!