Reactome | PRDX1 [cytosol]

PRDX1 [cytosol]

Stable Identifier

R-HSA-3341270

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peroxiredoxin-1 ecNumber1.11.1.15/ecNumber, PRDX1_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q06830 PRDX1

Gene Names

PRDX1, PAGA, PAGB, TDPX2

Chain

initiator methionine:1, chain:2-199

Reference Genes

BioGPS Gene:5052 PRDX1

COSMIC (genes):PRDX1 PRDX1

CTD Gene:5052 PRDX1

dbSNP Gene:5052 PRDX1

ENSEMBL:ENSG00000117450 PRDX1

ENSEMBL_homo_sapiens_GENE:ENSG00000117450 PRDX1

HGNC:9352 PRDX1

KEGG Gene (Homo sapiens):5052 PRDX1

Monarch:5052 PRDX1

NCBI Gene:5052 PRDX1

OMIM:176763 PRDX1

UCSC:Q06830 PRDX1

Reference Transcript

Other Identifiers

0004070072

00480+1.11.1.15

11742924_a_at

16686472

208680_at

2410244

2410245

2410246

2410247

2410248

2410249

2410250

2410252

2410253

2RII

3198940

3HY2

41213_at

4682

4XCS

5052

7730

7915733

A0A0A0MRQ5

A_23_P11995

A_33_P3377199

AAA50464

AAH07063

AAH21683

AAV38545

ABB84465

BAG70076

BAG70202

CAA48137

CAB004682

CAG28580

CAI13095

CAI13096

CAI13097

CCDS522

EAX06975

EAX06976

EAX06978

EAX06979

EAX06980

EAX06981

EAX06982

ENSG00000117450

ENSP00000262746

ENSP00000361152

ENST00000262746

ENST00000319248

EntrezGene:5052

g440305_3p_s_at

GE62148

GO:0000302

GO:0001501

GO:0001895

GO:0002376

GO:0003674

GO:0003723

GO:0004601

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005634

GO:0005737

GO:0005829

GO:0006464

GO:0006950

GO:0006979

GO:0007165

GO:0008150

GO:0008283

GO:0008379

GO:0009056

GO:0016209

GO:0016491

GO:0019430

GO:0030101

GO:0031410

GO:0032872

GO:0034101

GO:0034599

GO:0042267

GO:0042470

GO:0042592

GO:0042744

GO:0042802

GO:0043209

GO:0043226

GO:0045296

GO:0045454

GO:0048856

GO:0051186

GO:0051920

GO:0055114

GO:0070062

GO:1901222

HGNC:9352

HPA007730

ILMN_1710159

ILMN_2366388

ILMN_2366391

IPR000866

IPR013766

IPR019479

IPR024706

IPR036249

MIM:176763

MIM:277400

NM_001202431

NM_002574

NM_181696

NM_181697

NP_001189360

NP_002565

NP_859047

NP_859048

PF00578

PF10417

PH_hs_0029347

PRDX1

PRDX1-201

PRDX1-202

TC01002611.hg

uc001coa.4

uc001cob.4

UPI000002FC88

X67951_at

Participant Of

input

CDK5:p25 phosphorylates PRDX1

hasComponent

Other forms of this molecule

p-T90-PRDX1 [cytosol]

HOOS-C52-PRDX1 [cytosol]

Inferred To

PRDX1 [cytosol] (Arabidopsis thaliana)

PRDX1 [cytosol] (Bos taurus)

PRDX1 [cytosol] (Caenorhabditis elegans)

PRDX1 [cytosol] (Canis familiaris)

PRDX1 [cytosol] (Danio rerio)

PRDX1 [cytosol] (Dictyostelium discoideum)

PRDX1 [cytosol] (Drosophila melanogaster)

PRDX1 [cytosol] (Gallus gallus)

PRDX1 [cytosol] (Oryza sativa)

PRDX1 [cytosol] (Plasmodium falciparum)

PRDX1 [cytosol] (Rattus norvegicus)

PRDX1 [cytosol] (Saccharomyces cerevisiae)

PRDX1 [cytosol] (Schizosaccharomyces pombe)

PRDX1 [cytosol] (Sus scrofa)

PRDX1 [cytosol] (Taeniopygia guttata)

PRDX1 [cytosol] (Xenopus tropicalis)

Homologues of PRDX1 [cytosol] (Arabidopsis thaliana)

Homologues of PRDX1 [cytosol] (Caenorhabditis elegans)

Homologues of PRDX1 [cytosol] (Canis familiaris)

Homologues of PRDX1 [cytosol] (Danio rerio)

Homologues of PRDX1 [cytosol] (Drosophila melanogaster)

Homologues of PRDX1 [cytosol] (Plasmodium falciparum)

Homologues of PRDX1 [cytosol] (Rattus norvegicus)

Homologues of PRDX1 [cytosol] (Saccharomyces cerevisiae)

Homologues of PRDX1 [cytosol] (Sus scrofa)

Prdx1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_859047.1, NP_001189360.1, NP_002565.1, NP_859048.1

OpenTargets

ENSG00000117450

GeneCards

Q06830

DOCK Blaster

2RII, 3HY2, 4XCS

PRO

Q06830

BRENDA (Homo sapiens)

1.11.1.15

HMDB Protein

HMDBP02990

PDB

4XCS, 3HY2, 2RII

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13043 STK4	4	STK4(1-487) [cytosol] (R-HSA-201627) p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682) STK4(327-487) [cytosol] (R-HSA-2028668)	0.66	11
UniProt:P60484 PTEN	41	PTEN [nucleoplasm] (R-HSA-5690148) K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379) PTEN C124Y [cytosol] (R-HSA-2317464) PTEN R130P [cytosol] (R-HSA-2317432) PTEN C124F [cytosol] (R-HSA-2317461) PTEN G129V [cytosol] (R-HSA-2318503) PTEN S170I [cytosol] (R-HSA-2318455) PTEN S170G [cytosol] (R-HSA-2318465) PTEN R233* [cytosol] (R-HSA-2318573) PTEN R335* [cytosol] (R-HSA-2318568) PTEN R130* [cytosol] (R-HSA-2318571) MonoUb-K13,K289-PTEN [cytosol] (R-HSA-6807247) MonoUb-K13,K289-PTEN [nucleoplasm] (R-HSA-6807264) PTEN [nucleoplasm] (R-HSA-6807273) p-Y336-PTEN [cytosol] (R-HSA-8847980) K27polyUb-PTEN [cytosol] (R-HSA-8851009) RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948798) PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948841) K48polyUb-K289-PTEN [cytosol] (R-HSA-8948777) PTEN [cytosol] (R-HSA-199420) p-3S,2T-PTEN [cytosol] (R-HSA-8850936) PolyUb-PTEN [cytosol] (R-HSA-6807280)	0.632	7
UniProt:Q9BYN0 SRXN1			0.618	3
UniProt:P10275 AR	4	SUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984) AR [cytosol] (R-HSA-5618082) AR [nucleoplasm] (R-HSA-446174)	0.544	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P54274 TERF1	1	TERF1 [nucleoplasm] (R-HSA-164618)	0.508	2
UniProt:Q00005 2ABB			0.462	2