Reactome | PRDX1 [cytosol]

PRDX1

Stable Identifier

R-HSA-3341270

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Synonyms

Peroxiredoxin-1 ecNumber1.11.1.15/ecNumber, PRDX1_HUMAN

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:Q06830 PRDX1

Gene Names

PRDX1, PAGA, PAGB, TDPX2

Chain

initiator methionine:1, chain:2-199

Reference Genes

BioGPS Gene:5052 PRDX1

COSMIC (genes):PRDX1 PRDX1

CTD Gene:5052 PRDX1

dbSNP Gene:5052 PRDX1

ENSEMBL:ENSG00000117450 PRDX1

HGNC:9352 PRDX1

KEGG Gene (Homo sapiens):hsa:5052 PRDX1

Monarch:5052 PRDX1

NCBI Gene:5052 PRDX1

OMIM:176763 PRDX1

UCSC:Q06830 PRDX1

Reference Transcript

Other Identifiers

0004070072

00480+1.11.1.15

11742924_a_at

16686472

208680_at

2410244

2410245

2410246

2410247

2410248

2410249

2410250

2410252

2410253

2RII

3198940

3HY2

41213_at

4682

4XCS

5052

7730

7915733

A0A0A0MRQ5

A0A0A0MSI0

A_23_P11995

A_33_P3377199

AAA50464

AAH07063

AAH21683

AAV38545

AB451262

AB451388

ABB84465

AL451136

BAG70076

BAG70202

BC007063

BC021683

BT019740

CAA48137

CAB004682

CAG28580

CAI13095

CAI13096

CAI13097

CCDS522

CH471059

CR407652

DQ297142

EAX06975

EAX06976

EAX06978

EAX06979

EAX06980

EAX06981

EAX06982

ENSG00000117450

ENSP00000262746

ENSP00000361152

ENST00000262746

ENST00000319248

EntrezGene:5052

g440305_3p_s_at

GE62148

GO:0000302

GO:0001501

GO:0001895

GO:0002376

GO:0003674

GO:0003723

GO:0004601

GO:0005515

GO:0005575

GO:0005576

GO:0005615

GO:0005622

GO:0005623

GO:0005634

GO:0005737

GO:0005829

GO:0006464

GO:0006950

GO:0006979

GO:0007165

GO:0008150

GO:0008283

GO:0008379

GO:0009056

GO:0016209

GO:0016491

GO:0019430

GO:0030101

GO:0031410

GO:0032872

GO:0034101

GO:0034599

GO:0042267

GO:0042470

GO:0042592

GO:0042744

GO:0042802

GO:0043209

GO:0043226

GO:0045296

GO:0045454

GO:0048856

GO:0051186

GO:0051920

GO:0055114

GO:0070062

GO:1901222

HGNC:9352

HPA007730

ILMN_1710159

ILMN_2366388

ILMN_2366391

IPR000866

IPR013766

IPR019479

IPR024706

IPR036249

L19184

MIM:176763

MIM:277400

NM_001202431

NM_002574

NM_181696

NM_181697

NP_001189360

NP_002565

NP_859047

NP_859048

PF00578

PF10417

PH_hs_0029347

PRDX1

PRDX1-201

PRDX1-202

TC01002611.hg

uc001coa.4

uc001cob.4

UPI000002FC88

X67951

X67951_at

Participant Of

input

CDK5:p25 phosphorylates PRDX1

hasComponent

Other forms of this molecule

p-T90-PRDX1 [cytosol]

HOOS-C52-PRDX1 [cytosol]

Inferred To

PRDX1 [cytosol] (Arabidopsis thaliana)

PRDX1 [cytosol] (Bos taurus)

PRDX1 [cytosol] (Caenorhabditis elegans)

PRDX1 [cytosol] (Canis familiaris)

PRDX1 [cytosol] (Danio rerio)

PRDX1 [cytosol] (Dictyostelium discoideum)

PRDX1 [cytosol] (Drosophila melanogaster)

PRDX1 [cytosol] (Gallus gallus)

PRDX1 [cytosol] (Oryza sativa)

PRDX1 [cytosol] (Plasmodium falciparum)

PRDX1 [cytosol] (Rattus norvegicus)

PRDX1 [cytosol] (Saccharomyces cerevisiae)

PRDX1 [cytosol] (Schizosaccharomyces pombe)

PRDX1 [cytosol] (Sus scrofa)

PRDX1 [cytosol] (Taeniopygia guttata)

PRDX1 [cytosol] (Xenopus tropicalis)

Homologues of PRDX1 [cytosol] (Arabidopsis thaliana)

Homologues of PRDX1 [cytosol] (Caenorhabditis elegans)

Homologues of PRDX1 [cytosol] (Canis familiaris)

Homologues of PRDX1 [cytosol] (Danio rerio)

Homologues of PRDX1 [cytosol] (Drosophila melanogaster)

Homologues of PRDX1 [cytosol] (Plasmodium falciparum)

Homologues of PRDX1 [cytosol] (Rattus norvegicus)

Homologues of PRDX1 [cytosol] (Saccharomyces cerevisiae)

Homologues of PRDX1 [cytosol] (Sus scrofa)

Prdx1 [cytosol] (Mus musculus)

Cross References

RefSeq

NP_859047.1, NP_001189360.1, NP_859048.1, NP_002565.1

GeneCards

Q06830

PRO

Q06830

BRENDA (Homo sapiens)

1.11.1.15

HMDB Protein

HMDBP02990

PDB

2RII, 4XCS, 3HY2

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:Q13043 STK4	4	STK4(1-487) [cytosol] (R-HSA-201627) p-T183-STK4(1-487) [cytosol] (R-HSA-2028258) p-T183-STK4(1-326) [cytosol] (R-HSA-2028682) STK4(327-487) [cytosol] (R-HSA-2028668)	0.66	11
UniProt:P60484 PTEN	41	PTEN [nucleoplasm] (R-HSA-5690148) K48polyUb-PTEN [cytosol] (R-HSA-8874327) PolyUb-PTEN [nucleoplasm] (R-HSA-6782515) PTEN H93R [cytosol] (R-HSA-2318524) PTEN C124R [cytosol] (R-HSA-2317439) PTEN H93Y [cytosol] (R-HSA-2318520) PTEN R130G [cytosol] (R-HSA-2317339) PTEN H93D [cytosol] (R-HSA-2318550) PTEN R130L [cytosol] (R-HSA-2317430) PTEN H93A [cytosol] (R-HSA-2318544) PTEN G129E [cytosol] (R-HSA-2318509) PTEN S170N [cytosol] (R-HSA-2318408) PTEN R173P [cytosol] (R-HSA-2317480) PTEN R130Q [cytosol] (R-HSA-2317416) PTEN H93Q [cytosol] (R-HSA-2318565) PTEN G129R [cytosol] (R-HSA-2318501) PTEN H123Y [cytosol] (R-HSA-2318469) PTEN S170R [cytosol] (R-HSA-2318437) PTEN R173C [cytosol] (R-HSA-2317478) PTEN R173H [cytosol] (R-HSA-2317473) PTEN C124S [cytosol] (R-HSA-2317379) PTEN C124Y [cytosol] (R-HSA-2317464) PTEN R130P [cytosol] (R-HSA-2317432) PTEN C124F [cytosol] (R-HSA-2317461) PTEN G129V [cytosol] (R-HSA-2318503) PTEN S170I [cytosol] (R-HSA-2318455) PTEN S170G [cytosol] (R-HSA-2318465) PTEN R233* [cytosol] (R-HSA-2318573) PTEN R335* [cytosol] (R-HSA-2318568) PTEN R130* [cytosol] (R-HSA-2318571) p-3S,2T-PTEN [cytosol] (R-HSA-8850936) RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948798) PolyUb-K324,K344,K349-RibC-E40,E150,D326-PTEN [cytosol] (R-HSA-8948841) PolyUb-PTEN [cytosol] (R-HSA-6807280) PTEN [cytosol] (R-HSA-199420) MonoUb-K13,K289-PTEN [cytosol] (R-HSA-6807247) MonoUb-K13,K289-PTEN [nucleoplasm] (R-HSA-6807264) PTEN [nucleoplasm] (R-HSA-6807273) p-Y336-PTEN [cytosol] (R-HSA-8847980) K27polyUb-PTEN [cytosol] (R-HSA-8851009) K48polyUb-K289-PTEN [cytosol] (R-HSA-8948777)	0.632	7
UniProt:Q9BYN0 SRXN1			0.618	3
UniProt:P10275 AR	4	SUMO1-K386,520-AR [nucleoplasm] (R-HSA-4090320) PolyUb-AR [nucleoplasm] (R-HSA-6782984) AR [nucleoplasm] (R-HSA-446174) AR [cytosol] (R-HSA-5618082)	0.544	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P54274 TERF1	1	TERF1 [nucleoplasm] (R-HSA-164618)	0.508	2
UniProt:Q00005 2ABB			0.462	2