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Cytochrome P450 (CYP2C19 based) [endoplasmic reticulum membrane]
Stable Identifier
R-HSA-3222363
Type
Set [CandidateSet]
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane
Locations in the PathwayBrowser
Expand all
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Xenobiotics (Homo sapiens)
CYP2C19 5-hydroxylates omeprazole (Homo sapiens)
Cytochrome P450 (CYP2C19 based) [endoplasmic reticulum membrane] (Homo sapiens)
General
This CandidateSet contains sequences identified by William Pearson's analysis of Reactome catalyst entities. Catalyst entity sequences were used to identify analagous sequences that shared overall homology and active site homology. Sequences in this Candidate set were identified in an April 24, 2012 analysis. Further candidates were identified by Ralf Stephan in a July 15, 2023 analysis.
Literature References
PubMed ID
Title
Journal
Year
Catalyst Sequence Similarity Project
Pearson, W
Participants
members
CYP2C19 [endoplasmic reticulum membrane]
(Homo sapiens)
candidates
CYP2C9 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2C8 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2E1 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2F1 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2A7 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2B6 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2S1 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2D6 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2A13 [endoplasmic reticulum membrane]
(Homo sapiens)
CYP2C18 [endoplasmic reticulum membrane]
(Homo sapiens)
Inferred To
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Bos taurus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Caenorhabditis elegans)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Dictyostelium discoideum)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Drosophila melanogaster)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Gallus gallus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Mus musculus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Rattus norvegicus)
Cytochrome P450 (CYP2C8 based) [endoplasmic reticulum membrane]
(Sus scrofa)
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