Reactome | PIM1 [nucleoplasm]

PIM1 [nucleoplasm]

Stable Identifier

R-HSA-3215094

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

Serine/threonine-protein kinase pim-1

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P11309 PIM1

Gene Names

PIM1

Chain

chain:1-313

Reference Genes

COSMIC (genes):PIM1 PIM1

dbSNP Gene:5292 PIM1

ENSEMBL:ENSG00000137193 PIM1

Participates

as a member of

STAT3-upregulated nuclear proteins [nucleoplasm] (Homo sapiens)

as an output of

STAT5-dependent PIM1 gene expression downstream of FLT3 ITD and fusion mutants (Homo sapiens)

Interactors (12)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P39019 RPS19	2	RPS19 [cytosol] (R-HSA-72343) RPS19 [nucleoplasm] (R-HSA-6798710)	0.633	7
UniProt:P51116 FXR2			0.556	3
UniProt:Q8N7W2-2 BEND7			0.556	3
UniProt:Q96MH2 HEXI2			0.556	3
UniProt:P0C1Z6-2 TFPT			0.556	3
UniProt:Q8N9N5 BANP	1	BANP [nucleoplasm] (R-HSA-3221973)	0.556	3
UniProt:Q9Y2K1 ZBTB1			0.556	3
UniProt:Q5T203 Q5T203			0.556	3
UniProt:P07954 FH	1	FH [mitochondrial matrix] (R-HSA-70980)	0.556	3
UniProt:P00533 EGFR	20	p-6Y-EGFR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869138) p-5Y-EGFRvIII [plasma membrane] (R-HSA-1248649) EGFRvIII [plasma membrane] (R-HSA-1214162) p-6Y-EGFR E746_A750del;T790M [plasma membrane] (R-HSA-1182985) p-6Y-EGFR L858R;T790M [plasma membrane] (R-HSA-1182984) p-6Y-EGFR A767_V769dup [plasma membrane] (R-HSA-1996343) p-6Y-EGFR N771_H773dup [plasma membrane] (R-HSA-1996342) p-6Y-EGFR K739_I744dup [plasma membrane] (R-HSA-1996346) p-6Y-EGFR D770_N771insNPG [plasma membrane] (R-HSA-1996335) p-6Y-EGFR E746_A750del [plasma membrane] (R-HSA-1181214) p-6Y-EGFR L858R [plasma membrane] (R-HSA-1173211) p-6Y-EGFR G719S [plasma membrane] (R-HSA-1169417) p-6Y-EGFR L747_P753delinsS [plasma membrane] (R-HSA-1228038) p-6Y-EGFR L747_A750delinsP [plasma membrane] (R-HSA-1228044) p-6Y-EGFR L747_T751del [plasma membrane] (R-HSA-1228041) p-6Y-EGFR L747_S752del [plasma membrane] (R-HSA-1228040) p-6Y-EGFR L747_T751delinsP [plasma membrane] (R-HSA-1228042) p-6Y-EGFR E746_T751delinsA [plasma membrane] (R-HSA-1228037) p-6Y-EGFR E746_S752delinsV [plasma membrane] (R-HSA-1228039) p-6Y-EGFR L861Q [plasma membrane] (R-HSA-1177541)	0.553	2
UniProt:P27448 MARK3	1	MARK3 [cytosol] (R-HSA-5672591)	0.527	2
UniProt:Q96F86 EDC3	1	EDC3 [cytosol] (R-HSA-429997)	0.527	3

Cite Us!