Reactome | RPS19 [nucleoplasm]

RPS19 [nucleoplasm]

Stable Identifier

R-HSA-6798710

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

40S small ribosomal protein 19, P39019, 40S ribosomal protein S19

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:P39019 RPS19

Gene Names

RPS19

Chain

initiator methionine:1, chain:2-145

Reference Genes

BioGPS Gene:6223 RPS19

COSMIC (genes):RPS19 RPS19

CTD Gene:6223 RPS19

dbSNP Gene:6223 RPS19

ENSEMBL:ENSG00000105372 RPS19

ENSEMBL:ENSG00000105372.8 RPS19

HGNC:10402 RPS19

KEGG Gene (Homo sapiens):6223 RPS19

Monarch:6223 RPS19

NCBI Gene:6223 RPS19

OMIM:603474 RPS19

UCSC:P39019 RPS19

Reference Transcript

Other Identifiers

11744046_at

11756327_x_at

16862596

202649_3p_x_at

202649_PM_x_at

202649_x_at

213414_3p_s_at

213414_PM_s_at

213414_s_at

31330_at

3560633

3834468

3834469

3834470

3834471

3834473

3834474

3834475

3834488

3834489

3834492

3834496

3834497

3834498

3834499

3878464

6223

79903_f_at

8029129

A_24_P134074

A_24_P65597

GE85881

GO:0000028

GO:0000462

GO:0002181

GO:0002376

GO:0002548

GO:0003723

GO:0003735

GO:0005198

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005730

GO:0005737

GO:0005829

GO:0005840

GO:0005925

GO:0006364

GO:0006412

GO:0006954

GO:0007000

GO:0009991

GO:0014069

GO:0016020

GO:0017134

GO:0019901

GO:0022626

GO:0022627

GO:0030154

GO:0030218

GO:0030490

GO:0031640

GO:0032040

GO:0042254

GO:0042274

GO:0042802

GO:0043226

GO:0048856

GO:0048870

GO:0050829

GO:0060265

GO:0060266

GO:0061844

GO:0065003

GO:0070062

GO:0098542

GO:1990904

HMNXSV003047115

Hs.298262.1.S1_3p_a_at

Hs.298262.1.S1_3p_x_at

ILMN_1784717

M81757_at

TC19000587.hg

g4506694_3p_a_at

g4506694_3p_at

Participates

as a component of

18SE pre-40S particle [nucleoplasm] (Homo sapiens)

Other forms of this molecule

RPS19 [cytosol]

Inferred To

Rps19 [nucleoplasm] (Mus musculus)

Rps19 [nucleoplasm] (Rattus norvegicus)

RpS19a [nucleoplasm] (Drosophila melanogaster)

rps1901 [nucleoplasm] (Schizosaccharomyces pombe)

RPS19 [nucleoplasm] (Bos taurus)

RPS19 [nucleoplasm] (Canis familiaris)

RPS19 [nucleoplasm] (Danio rerio)

RPS19 [nucleoplasm] (Gallus gallus)

RPS19 [nucleoplasm] (Plasmodium falciparum)

RPS19 [nucleoplasm] (Sus scrofa)

RPS19A [nucleoplasm] (Saccharomyces cerevisiae)

rps19 [nucleoplasm] (Dictyostelium discoideum)

rps19 [nucleoplasm] (Xenopus tropicalis)

Homologues of RPS19 [nucleoplasm] (Bos taurus)

Homologues of RPS19 [nucleoplasm] (Saccharomyces cerevisiae)

RPS19B [nucleoplasm] (Saccharomyces cerevisiae)

rps-19 [nucleoplasm] (Caenorhabditis elegans)

Cross References

RefSeq

NP_001308413.1, NP_001308412.1, NP_001013.1

OpenTargets

ENSG00000105372

HPA

ENSG00000105372-RPS19

GeneCards

P39019

Ensembl

ENSP00000469228, ENSG00000105372, ENST00000600467, ENST00000598742, ENSP00000470004, ENSP00000470972, ENST00000593863

PRO

P39019

Pharos - Targets

P39019

Orphanet

15229

PDB

6QZP, 6Z6L, 6YBS, 6IP5, 6ZMO, 6ZV6, 7TQL, 6ZMI, 7WTV, 7R4X, 6OLG, 6ZUO, 7WTW, 5VYC, 6XA1, 7MQA, 5LKS, 6G4W, 6ZXG, 6ZME, 6ZOL, 7WTX, 6ZXF, 7WTZ, 6ZN5, 6G18, 6ZVJ, 6Z6N, 6G51, 6ZVH, 6Z6M, 6ZMW, 6G4S, 6ZM7, 6ZXD, 7A09, 6OM7, 6ZMT, 6ZLW, 6Y57, 6IP8, 7K5I, 4UG0, 6IP6, 5FLX, 6G5H, 5A2Q, 6OLZ, 7WTT, 6OM0, 7QP6, 7WTU, 6G5I, 7QP7, 6Y2L, 6Y0G, 6ZXH, 4V6X, 6OLI, 6ZP4, 6OLF, 5T2C, 6ZON, 6G53, 6OLE, 6ZXE, 7WU0, 5OA3, 5AJ0, 6ZOJ

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P11309 PIM1	1	PIM1 [nucleoplasm] (R-HSA-3215094)	0.633	7
UniProt:P63244 RACK1	1	GNB2L1 [cytosol] (R-HSA-5626956)	0.607	3
UniProt:P42858 HTT	1	HTT [nucleoplasm] (R-HSA-9023590)	0.556	3
UniProt:P19320 VCAM1	1	VCAM1 [plasma membrane] (R-HSA-197834)	0.527	4
UniProt:P13569 CFTR	17	PolyUb-CFTR [clathrin-coated endocytic vesicle membrane] (R-HSA-8869104) PolyUb-CFTR [plasma membrane] (R-HSA-8867595) CFTR [lysosomal membrane] (R-HSA-5627279) CFTR [Golgi-associated vesicle membrane] (R-HSA-5627079) CFTR [endosome membrane] (R-HSA-6782965) PolyUb-CFTR [endosome membrane] (R-HSA-6782976) CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866834) ub-CFTR F508del [cytosol] (R-HSA-8866838) ub-CFTR F508del [endoplasmic reticulum membrane] (R-HSA-8866842) CFTR G542* [plasma membrane] (R-HSA-5678986) CFTR G551D [plasma membrane] (R-HSA-5678977) CFTR W1282* [plasma membrane] (R-HSA-5678976) CFTR F508del [plasma membrane] (R-HSA-5678978) CFTR N1303K [plasma membrane] (R-HSA-5678983) CFTR [plasma membrane] (R-HSA-383188) CFTR [endoplasmic reticulum membrane] (R-HSA-8866837) misfolded CFTR [endoplasmic reticulum membrane] (R-HSA-8868730)	0.483	10

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