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DHX36 [cytosol]
Stable Identifier
R-HSA-3134862
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
DEx/H-box helicases activate type I IFN and inflammatory cytokines production (Homo sapiens)
DHX36 binds DNA (Homo sapiens)
DHX36 [cytosol] (Homo sapiens)
DHX36:CpG [cytosol] (Homo sapiens)
DHX36 [cytosol] (Homo sapiens)
DHX36 or DHX9 binds MyD88 (Homo sapiens)
DHX9/DHX36:CpG [cytosol] (Homo sapiens)
DHX36:CpG [cytosol] (Homo sapiens)
DHX36 [cytosol] (Homo sapiens)
DHX9/DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
DHX36:CpG [cytosol] (Homo sapiens)
DHX36 [cytosol] (Homo sapiens)
p-IRF7:p-IRF7 translocates to the nucleus (Homo sapiens)
DHX36:CpG:MyD88 [cytosol] (Homo sapiens)
DHX36:CpG [cytosol] (Homo sapiens)
DHX36 [cytosol] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q9H2U1 DHX36
Gene Names
DHX36, DDX36, KIAA1488, MLEL1, RHAU
Chain
chain:1-1008
Reference Genes
BioGPS Gene:170506 DHX36
COSMIC (genes):DHX36 DHX36
CTD Gene:170506 DHX36
dbSNP Gene:170506 DHX36
ENSEMBL:ENSG00000174953 DHX36
HGNC:14410 DHX36
KEGG:hsa:170506 DHX36
Monarch:170506 DHX36
NCBI Gene:170506 DHX36
OMIM:612767 DHX36
UCSC:Q9H2U1 DHX36
Reference Transcript
RefSeq:NM_001114397.1 DHX36
RefSeq:NM_020865.2 DHX36
Other Identifiers
11719502_a_at
11719503_a_at
11719504_a_at
11719505_x_at
11719506_a_at
1559039_PM_at
1559039_at
16960647
170506
223138_PM_s_at
223138_s_at
223139_PM_s_at
223139_s_at
223140_PM_s_at
223140_s_at
2701592
2701594
2701596
2701597
2701598
2701599
2701600
2701601
2701602
2701603
2701604
2701606
2701609
2701610
2701611
2701612
2701613
2701616
2701617
2701618
2701619
2701621
2701622
2701623
2701624
2701625
2701626
2701627
2701628
2701629
2701630
2701631
2701633
2701634
2701635
2701636
2701637
2701638
2701641
2701642
2701643
46701_at
47054_at
77514_at
8091562
84966_r_at
A_23_P57697
GE88187
GO:0000287
GO:0000781
GO:0000976
GO:0000978
GO:0001503
GO:0002151
GO:0002376
GO:0002735
GO:0003676
GO:0003677
GO:0003678
GO:0003697
GO:0003723
GO:0003724
GO:0003725
GO:0003730
GO:0003824
GO:0004386
GO:0005515
GO:0005524
GO:0005634
GO:0005654
GO:0005694
GO:0005737
GO:0005739
GO:0005829
GO:0006355
GO:0006359
GO:0006417
GO:0007283
GO:0008094
GO:0009615
GO:0010494
GO:0010501
GO:0010628
GO:0016020
GO:0016607
GO:0016787
GO:0016887
GO:0017148
GO:0022414
GO:0030154
GO:0030424
GO:0030425
GO:0031442
GO:0032206
GO:0032508
GO:0032727
GO:0034605
GO:0034644
GO:0035925
GO:0042826
GO:0042995
GO:0043123
GO:0043204
GO:0043226
GO:0043330
GO:0043488
GO:0044806
GO:0045087
GO:0045944
GO:0045995
GO:0046872
GO:0048027
GO:0051607
GO:0051880
GO:0051891
GO:0060261
GO:0061003
GO:0061158
GO:0070034
GO:0070062
GO:0070883
GO:0090669
GO:0098542
GO:0140097
GO:0140098
GO:0140657
GO:1900153
GO:1901534
GO:1903843
GO:1904358
GO:1904582
GO:2000767
HMNXSV003002164
Hs.9414.0.S1_3p_a_at
Hs.9414.0.S2_3p_a_at
Hs2.379369.1.A1_3p_at
ILMN_1738272
ILMN_2100000
PH_hs_0000977
TC03001919.hg
g11526792_3p_a_at
Participates
as a component of
DHX36:CpG [cytosol] (Homo sapiens)
as an input of
DHX36 binds DNA (Homo sapiens)
Inferred To
DHX36 [cytosol]
(Bos taurus)
DHX36 [cytosol]
(Canis familiaris)
DHX36 [cytosol]
(Gallus gallus)
DHX36 [cytosol]
(Mus musculus)
DHX36 [cytosol]
(Rattus norvegicus)
DHX36 [cytosol]
(Sus scrofa)
dhx9 [cytosol]
(Dictyostelium discoideum)
Rhau [cytosol]
(Drosophila melanogaster)
dhx36 [cytosol]
(Xenopus tropicalis)
Cross References
RefSeq
NP_001107869.1
,
NP_065916.2
ENSEMBL
ENSP00000417078
,
ENST00000329463
,
ENSP00000330113
,
ENST00000308361
,
ENST00000496811
,
ENSP00000309296
OpenTargets
ENSG00000174953
IntEnz
3.6.4.13
HPA
ENSG00000174953-DHX36
PRO
Q9H2U1
Pharos - Targets
Q9H2U1
GlyGen
Q9H2U1
HMDB Protein
HMDBP11701
PDB
2N21
,
2N16
,
6Q6R
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P15976 GATA1
1
GATA1 [nucleoplasm]
(R-HSA-996772)
0.569
4
UniProt:Q9NRI5 DISC1
0.547
2
UniProt:Q9H9Z2 LIN28A
1
LIN28A [cytosol]
(R-HSA-500391)
0.527
2
UniProt:P0DTC9 N
13
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729340)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [endoplasmic reticulum-Golgi intermediate compartment membrane]
(R-COV-9729341)
ADPr-p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729275)
p-11S,2T-metR95,177-N [cytosol]
(R-COV-9729308)
p-11S,2T-N [cytosol]
(R-COV-9729264)
p-8S,2T-N [cytosol]
(R-COV-9729277)
p-8S-N [cytosol]
(R-COV-9729335)
p-S188,206-N [cytosol]
(R-COV-9729324)
N [cytosol]
(R-COV-9694300)
SUMO1-K62,ADPr-,p-11S,2T,met-R95,177,Ac-K375-N [cytosol]
(R-COV-9756489)
N [plasma membrane]
(R-COV-9694356)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [nucleolus]
(R-COV-9729339)
SUMO1-K62-ADPr-p-11S,2T-metR95,177-N [plasma membrane]
(R-COV-9729325)
0.527
2
UniProt:Q16629 SRSF7
1
SRSF7 [nucleoplasm]
(R-HSA-72029)
0.483
2
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