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EPHA7 [plasma membrane]
Stable Identifier
R-HSA-2682337
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ephrin type-A receptor 7 ecNumber2.7.10.1/ecNumber, EPHA7_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH receptors autophosphorylate (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
ADAM10 cleaves EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs:ADAM10 [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH:EFN dimers tetramerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH:EFN tetramers oligomerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs bind EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15375 EPHA7
Gene Names
EPHA7, EHK3, HEK11
Chain
signal peptide:1-27, chain:28-998
Reference Genes
BioGPS Gene:2045 EPHA7
COSMIC (genes):EPHA7 EPHA7
CTD Gene:2045 EPHA7
dbSNP Gene:2045 EPHA7
ENSEMBL:ENSG00000135333.15 EPHA7
HGNC:3390 EPHA7
KEGG Gene (Homo sapiens):2045 EPHA7
Monarch:2045 EPHA7
NCBI Gene:2045 EPHA7
OMIM:602190 EPHA7
UCSC:Q15375 EPHA7
Reference Transcript
RefSeq:XM_005248669.2 EPHA7
RefSeq:NM_001288629.1 EPHA7
RefSeq:NM_004440.3 EPHA7
RefSeq:NM_001288630.1 EPHA7
Other Identifiers
11726161_at
11726162_at
11726163_at
11726164_at
11761670_at
1485_at
1554629_PM_at
1554629_at
17021792
2045
206852_PM_at
206852_at
229288_PM_at
229288_at
238533_PM_at
238533_at
2965208
2965209
2965210
2965211
2965213
2965214
2965216
2965218
2965219
2965221
2965222
2965223
2965224
2965235
2965236
2965237
2965244
2965245
2965246
2965247
2965258
2965259
2965260
46092_at
8128284
82275_at
A_23_P7835
A_24_P226332
A_24_P34031
GE80563
GO:0000166
GO:0001934
GO:0003824
GO:0004672
GO:0004713
GO:0004714
GO:0005003
GO:0005004
GO:0005005
GO:0005515
GO:0005524
GO:0005886
GO:0005887
GO:0006468
GO:0006915
GO:0007155
GO:0007169
GO:0007399
GO:0007411
GO:0007420
GO:0008046
GO:0012501
GO:0016020
GO:0016021
GO:0016301
GO:0016310
GO:0016740
GO:0018108
GO:0019838
GO:0022407
GO:0023052
GO:0030154
GO:0030425
GO:0031290
GO:0031594
GO:0031952
GO:0033674
GO:0034330
GO:0036211
GO:0043005
GO:0043025
GO:0043065
GO:0043226
GO:0043235
GO:0043281
GO:0043525
GO:0045211
GO:0045499
GO:0046875
GO:0048013
GO:0048018
GO:0048671
GO:0048755
GO:0048856
GO:0050730
GO:0050804
GO:0050919
GO:0051402
GO:0051964
GO:0060089
GO:0070372
GO:0072178
GO:0098685
GO:0098686
GO:0098772
GO:0098839
GO:0098978
GO:0099175
GO:0099634
GO:0140096
HMNXSV003009617
HMNXSV003011390
HMNXSV003017116
Hs.134736.0.A1_3p_at
Hs.54709.0.S1_3p_at
Hs2.165708.1.S1_3p_at
ILMN_1803637
L36642_at
PH_hs_0004229
TC06001952.hg
g4758281_3p_at
Participates
as a member of
EPHAs [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y608,Y614-EPHA7 [plasma membrane]
Inferred To
EPHA7 [plasma membrane]
(Bos taurus)
EPHA7 [plasma membrane]
(Canis familiaris)
EPHA7 [plasma membrane]
(Danio rerio)
EPHA7 [plasma membrane]
(Gallus gallus)
EPHA7 [plasma membrane]
(Mus musculus)
EPHA7 [plasma membrane]
(Rattus norvegicus)
EPHA7 [plasma membrane]
(Sus scrofa)
EPHA7 [plasma membrane]
(Xenopus tropicalis)
Cross References
RefSeq
XP_005248726.1
,
NP_001275558.1
,
NP_004431.1
,
NP_001275559.1
ZINC - World Drugs
EPHA7_HUMAN
Guide to Pharmacology - Targets
1827
OpenTargets
ENSG00000135333
ZINC - FDA approved
EPHA7_HUMAN
ZINC - Substances
EPHA7_HUMAN
ZINC target
Q15375
ZINC - Biogenic
EPHA7_HUMAN
PRO
Q15375
PDB
2REI
,
3NRU
,
7EEF
,
7EEC
,
3DKO
,
7EED
,
3H8M
ZINC - Investigational
EPHA7_HUMAN
IntEnz
2.7.10.1
HPA
ENSG00000135333-EPHA7
GeneCards
Q15375
Ensembl
ENSP00000506130
,
ENST00000680224
,
ENST00000369303
,
ENSP00000358303
,
ENST00000369297
,
ENSG00000135333
,
ENSP00000358309
Pharos - Targets
Q15375
Orphanet
24513
ZINC - Predictions - Purchasable
EPHA7_HUMAN
HMDB Protein
HMDBP01326
Interactors (3)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P29323 EPHB2
6
EPHB2 (?-?) [plasma membrane]
(R-HSA-3928394)
EPHB2 (?-1055) [cytosol]
(R-HSA-3928432)
EPHB2 (?-1055) [plasma membrane]
(R-HSA-3928386)
EPHB2 (19-?) [extracellular region]
(R-HSA-3928436)
EPHB2 [plasma membrane]
(R-HSA-443809)
p-Y596,Y602-EPHB2 [plasma membrane]
(R-HSA-3928375)
0.499
2
UniProt:Q16288 NTRK3
6
NTRK3(32-495) [plasma membrane]
(R-HSA-9603541)
NTRK3(642-839) [cytosol]
(R-HSA-9603540)
NTRK3 [plasma membrane]
(R-HSA-6798240)
NTRK3(496-641) [mitochondrial outer membrane]
(R-HSA-9603557)
NTRK3(496-641) [cytosol]
(R-HSA-9603542)
p-5Y-NTRK3 [plasma membrane]
(R-HSA-9034718)
0.499
2
UniProt:P07333 CSF1R
4
PolyUb,p-8Y-CSF1R [plasma membrane]
(R-HSA-389142)
PolyUb,p-Y561-CSF1R [plasma membrane]
(R-HSA-9733335)
p-Y561-CSF1R [plasma membrane]
(R-HSA-9733328)
CSF1R [plasma membrane]
(R-HSA-197667)
0.499
2
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