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EPHA7 [plasma membrane]
Stable Identifier
R-HSA-2682337
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Ephrin type-A receptor 7 ecNumber2.7.10.1/ecNumber, EPHA7_HUMAN
Locations in the PathwayBrowser
Expand all
Developmental Biology (Homo sapiens)
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH receptors autophosphorylate (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH-ephrin mediated repulsion of cells (Homo sapiens)
ADAM10 cleaves EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs:ADAM10 [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH:EFN dimers tetramerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH:EFN tetramers oligomerise (Homo sapiens)
EPH-EFN dimers [plasma membrane] (Homo sapiens)
EPHA:EFNA dimers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPH-ephrin oligomers [plasma membrane] (Homo sapiens)
EPHA:EFNA oligomers [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs,EPHBs:EFNBs [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs bind EFNAs (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
EPHAs:EFNAs [plasma membrane] (Homo sapiens)
EPHAs [plasma membrane] (Homo sapiens)
EPHA7 [plasma membrane] (Homo sapiens)
External Reference Information
External Reference
UniProt:Q15375 EPHA7
Gene Names
EPHA7, EHK3, HEK11
Chain
signal peptide:1-27, chain:28-998
Reference Genes
BioGPS Gene:2045 EPHA7
COSMIC (genes):EPHA7 EPHA7
CTD Gene:2045 EPHA7
dbSNP Gene:2045 EPHA7
ENSEMBL:ENSG00000135333 EPHA7
HGNC:3390 EPHA7
KEGG:hsa:2045 EPHA7
Monarch:2045 EPHA7
NCBI Gene:2045 EPHA7
OMIM:602190 EPHA7
UCSC:Q15375 EPHA7
Reference Transcript
RefSeq:NM_001288629.2 EPHA7
RefSeq:NM_001288630.2 EPHA7
RefSeq:NM_004440.4 EPHA7
RefSeq:XM_005248669.2 EPHA7
RefSeq:NM_001376465.1 EPHA7
Other Identifiers
11726161_at
11726162_at
11726163_at
11726164_at
11761670_at
1485_at
1554629_PM_at
1554629_at
17021792
2045
206852_PM_at
206852_at
229288_PM_at
229288_at
238533_PM_at
238533_at
2965208
2965209
2965210
2965211
2965212
2965213
2965214
2965215
2965216
2965218
2965219
2965220
2965221
2965222
2965223
2965224
2965231
2965232
2965233
2965234
2965235
2965236
2965237
2965244
2965245
2965246
2965247
2965249
2965250
2965251
2965252
2965258
2965259
2965260
46092_at
8128284
82275_at
A_23_P7835
A_24_P226332
A_24_P34031
GE80563
GO:0003824
GO:0004672
GO:0004713
GO:0005003
GO:0005004
GO:0005005
GO:0005006
GO:0005007
GO:0005008
GO:0005009
GO:0005010
GO:0005011
GO:0005018
GO:0005019
GO:0005020
GO:0005021
GO:0005515
GO:0005524
GO:0005886
GO:0006468
GO:0006915
GO:0007169
GO:0007173
GO:0007399
GO:0007411
GO:0007420
GO:0008046
GO:0008286
GO:0008288
GO:0008543
GO:0012501
GO:0016020
GO:0016310
GO:0016740
GO:0019838
GO:0022407
GO:0030425
GO:0031290
GO:0031547
GO:0031952
GO:0035790
GO:0035791
GO:0036323
GO:0036332
GO:0038062
GO:0038063
GO:0038084
GO:0038109
GO:0038145
GO:0043525
GO:0045499
GO:0048009
GO:0048012
GO:0048013
GO:0048018
GO:0048671
GO:0048755
GO:0048856
GO:0050730
GO:0050804
GO:0050919
GO:0051402
GO:0051964
GO:0060089
GO:0060175
GO:0070372
GO:0072178
GO:0098772
GO:0098978
GO:0099175
GO:0140096
HMNXSV003009617
HMNXSV003011390
HMNXSV003017116
Hs.134736.0.A1_3p_at
Hs.54709.0.S1_3p_at
Hs2.165708.1.S1_3p_at
ILMN_1803637
L36642_at
PH_hs_0004229
TC06001952.hg
g4758281_3p_at
p33909
Participates
as a member of
EPHAs [plasma membrane] (Homo sapiens)
Other forms of this molecule
p-Y608,Y614-EPHA7 [plasma membrane]
Inferred To
EPHA7 [plasma membrane]
(Bos taurus)
EPHA7 [plasma membrane]
(Canis familiaris)
EPHA7 [plasma membrane]
(Gallus gallus)
EPHA7 [plasma membrane]
(Sus scrofa)
Epha7 [plasma membrane]
(Mus musculus)
Epha7 [plasma membrane]
(Rattus norvegicus)
epha7 [plasma membrane]
(Danio rerio)
Cross References
RefSeq
NP_001363394.1
,
NP_001275559.1
,
NP_001275558.1
,
NP_004431.1
,
XP_005248726.1
ZINC - World Drugs
EPHA7_HUMAN
Guide to Pharmacology - Targets
1827
OpenTargets
ENSG00000135333
ENSEMBL
ENST00000680224
,
ENSP00000358303
,
ENST00000369303
,
ENST00000369297
,
ENSP00000358309
,
ENSP00000506130
,
ENSG00000135333
ZINC - FDA approved
EPHA7_HUMAN
ZINC - Substances
EPHA7_HUMAN
ZINC - Biogenic
EPHA7_HUMAN
ZINC target
Q15375
PRO
Q15375
GlyGen
Q15375
PDB
3NRU
,
3DKO
,
3H8M
,
7EEF
,
7EEC
,
2REI
,
7EED
ZINC - Investigational
EPHA7_HUMAN
IntEnz
2.7.10.1
HPA
ENSG00000135333-EPHA7
GeneCards
EPHA7
Pharos - Targets
Q15375
ZINC - Predictions - Purchasable
EPHA7_HUMAN
HMDB Protein
HMDBP01326
Interactors (5)
Accession
#Entities
Entities
Confidence Score
Evidence (IntAct)
UniProt:P34925 RYK
1
RYK [plasma membrane]
(R-HSA-3006746)
0.527
2
UniProt:Q16288 NTRK3
6
p-5Y-NTRK3 [plasma membrane]
(R-HSA-9034718)
NTRK3 [plasma membrane]
(R-HSA-6798240)
NTRK3(496-641) [cytosol]
(R-HSA-9603542)
NTRK3(496-641) [mitochondrial outer membrane]
(R-HSA-9603557)
NTRK3(642-839) [cytosol]
(R-HSA-9603540)
NTRK3(32-495) [plasma membrane]
(R-HSA-9603541)
0.499
2
UniProt:P07333 CSF1R
4
CSF1R [plasma membrane]
(R-HSA-197667)
p-Y561-CSF1R [plasma membrane]
(R-HSA-9733328)
PolyUb,p-Y561-CSF1R [plasma membrane]
(R-HSA-9733335)
PolyUb,p-8Y-CSF1R [plasma membrane]
(R-HSA-389142)
0.499
2
UniProt:P29323 EPHB2
6
p-Y596,Y602-EPHB2 [plasma membrane]
(R-HSA-3928375)
EPHB2 [plasma membrane]
(R-HSA-443809)
EPHB2 (19-?) [extracellular region]
(R-HSA-3928436)
EPHB2 (?-1055) [plasma membrane]
(R-HSA-3928386)
EPHB2 (?-1055) [cytosol]
(R-HSA-3928432)
EPHB2 (?-?) [plasma membrane]
(R-HSA-3928394)
0.499
2
UniProt:P31749 AKT1
14
p-T308,S473-AKT1 [nucleoplasm]
(R-HSA-198357)
p-T308,S473-AKT1 [cytosol]
(R-HSA-198356)
p-S473-AKT1 [plasma membrane]
(R-HSA-377265)
AKT1 [plasma membrane]
(R-HSA-199416)
AKT1 [cytosol]
(R-HSA-58252)
p-T308-AKT1 [cytosol]
(R-HSA-198634)
p-Y315,Y326-AKT1 [cytosol]
(R-HSA-8848757)
p-T308,S473-AKT1 [plasma membrane]
(R-HSA-199430)
p-S473-AKT1 [cytosol]
(R-HSA-9841264)
AKT1 E17K [plasma membrane]
(R-HSA-1500573)
p-S473-AKT1 E17K [plasma membrane]
(R-HSA-2243944)
AKT1 E17K [cytosol]
(R-HSA-2219526)
p-T308,S473-AKT1 E17K [cytosol]
(R-HSA-2243935)
p-T308,S473-AKT1 E17K [nucleoplasm]
(R-HSA-2399994)
0.471
2
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