Reactome | EPHA7 [plasma membrane]

EPHA7 [plasma membrane]

Stable Identifier

R-HSA-2682337

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

plasma membrane

Synonyms

Ephrin type-A receptor 7 ecNumber2.7.10.1/ecNumber, EPHA7_HUMAN

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q15375 EPHA7

Gene Names

EPHA7, EHK3, HEK11

Chain

signal peptide:1-27, chain:28-998

Reference Genes

BioGPS Gene:2045 EPHA7

COSMIC (genes):EPHA7 EPHA7

CTD Gene:2045 EPHA7

dbSNP Gene:2045 EPHA7

ENSEMBL:ENSG00000135333 EPHA7

HGNC:3390 EPHA7

KEGG:hsa:2045 EPHA7

Monarch:2045 EPHA7

NCBI Gene:2045 EPHA7

OMIM:602190 EPHA7

UCSC:Q15375 EPHA7

Reference Transcript

Other Identifiers

11726161_at

11726162_at

11726163_at

11726164_at

11761670_at

1485_at

1554629_PM_at

1554629_at

17021792

2045

206852_PM_at

206852_at

229288_PM_at

229288_at

238533_PM_at

238533_at

2965208

2965209

2965210

2965211

2965212

2965213

2965214

2965215

2965216

2965218

2965219

2965220

2965221

2965222

2965223

2965224

2965231

2965232

2965233

2965234

2965235

2965236

2965237

2965244

2965245

2965246

2965247

2965249

2965250

2965251

2965252

2965258

2965259

2965260

46092_at

8128284

82275_at

A_23_P7835

A_24_P226332

A_24_P34031

GE80563

GO:0003824

GO:0004672

GO:0004713

GO:0005003

GO:0005004

GO:0005005

GO:0005006

GO:0005007

GO:0005008

GO:0005009

GO:0005010

GO:0005011

GO:0005018

GO:0005019

GO:0005020

GO:0005021

GO:0005515

GO:0005524

GO:0005886

GO:0006468

GO:0006915

GO:0007169

GO:0007173

GO:0007399

GO:0007411

GO:0007420

GO:0008046

GO:0008286

GO:0008288

GO:0008543

GO:0012501

GO:0016020

GO:0016310

GO:0016740

GO:0019838

GO:0022407

GO:0030425

GO:0031290

GO:0031547

GO:0031952

GO:0035790

GO:0035791

GO:0036323

GO:0036332

GO:0038062

GO:0038063

GO:0038084

GO:0038109

GO:0038145

GO:0043525

GO:0045499

GO:0048009

GO:0048012

GO:0048013

GO:0048018

GO:0048671

GO:0048755

GO:0048856

GO:0050730

GO:0050804

GO:0050919

GO:0051402

GO:0051964

GO:0060089

GO:0060175

GO:0070372

GO:0072178

GO:0098772

GO:0098978

GO:0099175

GO:0140096

HMNXSV003009617

HMNXSV003011390

HMNXSV003017116

Hs.134736.0.A1_3p_at

Hs.54709.0.S1_3p_at

Hs2.165708.1.S1_3p_at

ILMN_1803637

L36642_at

PH_hs_0004229

TC06001952.hg

g4758281_3p_at

p33909

Participates

as a member of

EPHAs [plasma membrane] (Homo sapiens)

Other forms of this molecule

p-Y608,Y614-EPHA7 [plasma membrane]

Inferred To

EPHA7 [plasma membrane] (Bos taurus)

EPHA7 [plasma membrane] (Canis familiaris)

EPHA7 [plasma membrane] (Gallus gallus)

EPHA7 [plasma membrane] (Sus scrofa)

Epha7 [plasma membrane] (Mus musculus)

Epha7 [plasma membrane] (Rattus norvegicus)

epha7 [plasma membrane] (Danio rerio)

Cross References

RefSeq

NP_001363394.1, NP_001275559.1, NP_001275558.1, NP_004431.1, XP_005248726.1

ZINC - World Drugs

EPHA7_HUMAN

Guide to Pharmacology - Targets

1827

OpenTargets

ENSG00000135333

ENSEMBL

ENST00000680224, ENSP00000358303, ENST00000369303, ENST00000369297, ENSP00000358309, ENSP00000506130, ENSG00000135333

ZINC - FDA approved

EPHA7_HUMAN

ZINC - Substances

EPHA7_HUMAN

ZINC - Biogenic

EPHA7_HUMAN

ZINC target

Q15375

PRO

Q15375

GlyGen

Q15375

PDB

3NRU, 3DKO, 3H8M, 7EEF, 7EEC, 2REI, 7EED

ZINC - Investigational

EPHA7_HUMAN

IntEnz

2.7.10.1

HPA

ENSG00000135333-EPHA7

GeneCards

EPHA7

Pharos - Targets

Q15375

ZINC - Predictions - Purchasable

EPHA7_HUMAN

HMDB Protein

HMDBP01326

Interactors (5)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P34925 RYK	1	RYK [plasma membrane] (R-HSA-3006746)	0.527	2
UniProt:Q16288 NTRK3	6	p-5Y-NTRK3 [plasma membrane] (R-HSA-9034718) NTRK3 [plasma membrane] (R-HSA-6798240) NTRK3(496-641) [cytosol] (R-HSA-9603542) NTRK3(496-641) [mitochondrial outer membrane] (R-HSA-9603557) NTRK3(642-839) [cytosol] (R-HSA-9603540) NTRK3(32-495) [plasma membrane] (R-HSA-9603541)	0.499	2
UniProt:P07333 CSF1R	4	CSF1R [plasma membrane] (R-HSA-197667) p-Y561-CSF1R [plasma membrane] (R-HSA-9733328) PolyUb,p-Y561-CSF1R [plasma membrane] (R-HSA-9733335) PolyUb,p-8Y-CSF1R [plasma membrane] (R-HSA-389142)	0.499	2
UniProt:P29323 EPHB2	6	p-Y596,Y602-EPHB2 [plasma membrane] (R-HSA-3928375) EPHB2 [plasma membrane] (R-HSA-443809) EPHB2 (19-?) [extracellular region] (R-HSA-3928436) EPHB2 (?-1055) [plasma membrane] (R-HSA-3928386) EPHB2 (?-1055) [cytosol] (R-HSA-3928432) EPHB2 (?-?) [plasma membrane] (R-HSA-3928394)	0.499	2
UniProt:P31749 AKT1	14	p-T308,S473-AKT1 [nucleoplasm] (R-HSA-198357) p-T308,S473-AKT1 [cytosol] (R-HSA-198356) p-S473-AKT1 [plasma membrane] (R-HSA-377265) AKT1 [plasma membrane] (R-HSA-199416) AKT1 [cytosol] (R-HSA-58252) p-T308-AKT1 [cytosol] (R-HSA-198634) p-Y315,Y326-AKT1 [cytosol] (R-HSA-8848757) p-T308,S473-AKT1 [plasma membrane] (R-HSA-199430) p-S473-AKT1 [cytosol] (R-HSA-9841264) AKT1 E17K [plasma membrane] (R-HSA-1500573) p-S473-AKT1 E17K [plasma membrane] (R-HSA-2243944) AKT1 E17K [cytosol] (R-HSA-2219526) p-T308,S473-AKT1 E17K [cytosol] (R-HSA-2243935) p-T308,S473-AKT1 E17K [nucleoplasm] (R-HSA-2399994)	0.471	2