p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane]

Stable Identifier
R-HSA-2586513
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Leptin receptor, LEPR_HUMAN, LEPR, p-Y986,Y1079,Y1141-LEPR isoform 1
Icon
p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane] icon
p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane] icon
Locations in the PathwayBrowser
Expand all
Literature References
PubMed ID Title Journal Year
9020115 Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

White, DW, Kuropatwinski, KK, Baumann, H, Devos, R, Tartaglia, LA

J. Biol. Chem. 1997
9600917 Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

Symes, A, Stahl, N, Farruggella, TJ, Yancopoulos, GD, Carpenter, LR, Karow, ML

Proc. Natl. Acad. Sci. U.S.A. 1998
External Reference Information
External Reference
UniProt:P48357-1 LEPR
Gene Names
LEPR, DB, OBR
Other Identifiers
11726871_s_at
11734452_a_at
11738813_a_at
1556997_PM_a_at
1556997_a_at
207255_PM_at
207255_at
209894_PM_at
209894_at
211354_PM_s_at
211354_s_at
211355_PM_x_at
211355_x_at
211356_PM_x_at
211356_x_at
2340434
2340436
2340458
2340465
2340467
2340471
2340475
2340476
2340478
2340480
2340481
2340482
2340484
2340485
2340486
2340487
2340488
2340489
2340492
2340494
2340495
2340499
2340502
2340503
2340507
2340508
2340509
2340510
2340515
2340517
34266_at
34267_r_at
3953
7902074
A_14_P110946
A_14_P118866
A_23_P161135
A_24_P231104
A_33_P3303449
A_33_P3339820
GE506419
GE81143
GO:0001525
GO:0001934
GO:0002376
GO:0003013
GO:0004888
GO:0004896
GO:0005515
GO:0005576
GO:0005886
GO:0005975
GO:0005977
GO:0006091
GO:0006094
GO:0006112
GO:0006629
GO:0006909
GO:0006914
GO:0007166
GO:0007275
GO:0008203
GO:0009897
GO:0010507
GO:0014009
GO:0016020
GO:0016192
GO:0016323
GO:0019221
GO:0019953
GO:0019955
GO:0023052
GO:0030154
GO:0030217
GO:0033210
GO:0036211
GO:0038021
GO:0042593
GO:0042802
GO:0043235
GO:0044321
GO:0045721
GO:0046850
GO:0048856
GO:0051049
GO:0060089
GO:0060259
GO:0097009
GO:0098868
GO:0120162
GO:0150104
HMNXSV003040317
HMNXSV003041297
Hs2.258228.1.S1_3p_s_at
ILMN_1676265
ILMN_1696391
ILMN_1731966
ILMN_2234956
ILMN_2330570
PH_hs_0022042
PH_hs_0039985
TC01000730.hg
U66497_at
g1279902_3p_a_at
g3236285_3p_at
g4504978_3p_at
Participates
as a component of
Other forms of this molecule
LEPR-1 [plasma membrane]
Modified Residues
Name
O4'-phospho-L-tyrosine at 986
Coordinate
986
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1079
Coordinate
1079
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1141
Coordinate
1141
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
GeneCards
HPA
Ensembl
PRO
Pharos - Targets
Orphanet
PDB
Interactors (3)
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