p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane]

Stable Identifier
R-HSA-2586513
Type
Genes and Transcripts [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
plasma membrane
Synonyms
Leptin receptor, LEPR_HUMAN, LEPR, p-Y986,Y1079,Y1141-LEPR isoform 1
Icon
p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane] icon
p-Y986,Y1079,Y1141-LEPR-1 [plasma membrane] icon
Locations in the PathwayBrowser
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Literature References
PubMed ID Title Journal Year
9020115 Leptin receptor (OB-R) signaling. Cytoplasmic domain mutational analysis and evidence for receptor homo-oligomerization

White, DW, Kuropatwinski, KK, Devos, R, Baumann, H, Tartaglia, LA

J. Biol. Chem. 1997
9600917 Enhancing leptin response by preventing SH2-containing phosphatase 2 interaction with Ob receptor

Carpenter, LR, Farruggella, TJ, Symes, A, Karow, ML, Yancopoulos, GD, Stahl, N

Proc. Natl. Acad. Sci. U.S.A. 1998
External Reference Information
External Reference
UniProt:P48357-1 LEPR
Gene Names
LEPR, DB, OBR
Participates
as a component of
Other forms of this molecule
LEPR-1 [plasma membrane]
Modified Residues
Name
O4'-phospho-L-tyrosine at 986
Coordinate
986
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1079
Coordinate
1079
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Name
O4'-phospho-L-tyrosine at 1141
Coordinate
1141
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
Guide to Pharmacology - Targets
OpenTargets
ENSEMBL
HPA
GeneCards
PRO
Pharos - Targets
Orphanet
PDB
Interactors (3)
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