LEP [extracellular region]

Stable Identifier
R-HSA-400490
Type
Protein [EntityWithAccessionedSequence]
Species
Homo sapiens
Compartment
extracellular region
Synonyms
Leptin, LEP_HUMAN, Obesity factor, Obese protein
Locations in the PathwayBrowser
Expand all
External Reference Information
External Reference
UniProt:P41159 LEP
Gene Names
LEP, OB, OBS
Chain
signal peptide:1-21, chain:22-167
Reference Genes
BioGPS Gene:3952 LEP
COSMIC (genes):LEP LEP
CTD Gene:3952 LEP
dbSNP Gene:3952 LEP
ENSEMBL:ENSG00000174697 LEP
HGNC:6553 LEP
KEGG:hsa:3952 LEP
Monarch:3952 LEP
NCBI Gene:3952 LEP
OMIM:164160 LEP
UCSC:P41159 LEP
Reference Transcript
Other Identifiers
11735094_at
11735095_at
17051152
207092_3p_at
207092_PM_at
207092_at
3022734
3022741
3022742
3022743
3022744
3022745
3022746
3022756
3022757
3022758
35895_at
3831551
3952
8135909
A_14_P137267
A_24_P397817
D49487_s_at
GE87262
GO:0000122
GO:0001525
GO:0001542
GO:0001666
GO:0001819
GO:0001890
GO:0001932
GO:0001934
GO:0001936
GO:0002021
GO:0002376
GO:0003012
GO:0003013
GO:0003300
GO:0003677
GO:0005102
GO:0005179
GO:0005515
GO:0005576
GO:0005615
GO:0005737
GO:0005829
GO:0005975
GO:0006006
GO:0006091
GO:0006111
GO:0006112
GO:0006114
GO:0006355
GO:0006629
GO:0006635
GO:0006909
GO:0007155
GO:0007165
GO:0007565
GO:0007584
GO:0007623
GO:0008203
GO:0008206
GO:0008217
GO:0008284
GO:0008340
GO:0008343
GO:0009062
GO:0009892
GO:0010507
GO:0010888
GO:0014823
GO:0016192
GO:0019222
GO:0019953
GO:0021954
GO:0022414
GO:0022600
GO:0030073
GO:0030154
GO:0030217
GO:0030300
GO:0031667
GO:0032008
GO:0032099
GO:0032310
GO:0032355
GO:0032735
GO:0032755
GO:0032757
GO:0032760
GO:0032814
GO:0032817
GO:0032868
GO:0032869
GO:0033197
GO:0033210
GO:0033686
GO:0035360
GO:0035556
GO:0035630
GO:0035904
GO:0038108
GO:0042102
GO:0042269
GO:0042307
GO:0042445
GO:0042593
GO:0042755
GO:0043066
GO:0043270
GO:0043410
GO:0044320
GO:0045471
GO:0045598
GO:0045765
GO:0045906
GO:0046325
GO:0046427
GO:0046628
GO:0046850
GO:0046881
GO:0046890
GO:0048018
GO:0048639
GO:0048856
GO:0050796
GO:0050810
GO:0050892
GO:0050901
GO:0050999
GO:0051428
GO:0051541
GO:0051726
GO:0051897
GO:0060587
GO:0060612
GO:0061037
GO:0070093
GO:0071298
GO:0071300
GO:0090335
GO:0097009
GO:0098772
GO:0098868
GO:0120162
GO:1900015
GO:1900180
GO:1900745
GO:1901135
GO:1904651
GO:1990051
GO:1990460
GO:2000379
GO:2000486
GO:2000491
HMNXSV003046305
ILMN_1917153
ILMN_2207504
ILMN_2207505
PH_hs_0011466
TC07000768.hg
U43653_at
g4557714_3p_at
Participates
as an output of
as an input of
as a component of
This entity regulates
Negatively
Positively
Inferred To
lep [extracellular region] (Xenopus tropicalis)
Leptin [extracellular region] (Mus musculus)
ob [extracellular region] (Bos taurus)
Lep [extracellular region] (Rattus norvegicus)
LEP [extracellular region] (Canis familiaris)
LEP [extracellular region] (Sus scrofa)
lepb [extracellular region] (Danio rerio)
Cross References
RefSeq
ENSEMBL
OpenTargets
HPA
PRO
Pharos - Targets
Orphanet
LEP
HMDB Protein
PDB
Interactors (2)
Accession #Entities Entities Confidence Score Evidence (IntAct)
 UniProt:P48357 LEPR      0.59 3
 UniProt:O75031 HSF2B      0.556 3
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