Reactome | ERF [nucleoplasm]

ERF [nucleoplasm]

Stable Identifier

R-HSA-2534321

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

nucleoplasm

Synonyms

ETS domain-containing transcription factor ERF, Ets2 repressor factor, PE-2

Locations in the PathwayBrowser

Expand all

External Reference Information

External Reference

UniProt:P50548 ERF

Gene Names

ERF

Chain

chain:1-548

Reference Genes

BioGPS Gene:2077 ERF

COSMIC (genes):ERF ERF

CTD Gene:2077 ERF

dbSNP Gene:2077 ERF

ENSEMBL:ENSG00000105722 ERF

ENSEMBL_homo_sapiens_GENE:ENSG00000105722.10 ERF

HGNC:3444 ERF

KEGG Gene (Homo sapiens):2077 ERF

Monarch:2077 ERF

NCBI Gene:2077 ERF

OMIM:611888 ERF

UCSC:P50548 ERF

Reference Transcript

Other Identifiers

11718262_a_at

11718263_a_at

11748189_a_at

1242_at

16872760

203643_3p_at

203643_PM_at

203643_at

2077

3863303

3863548

3863549

3863550

3863551

3863552

3863553

3863554

3863555

3863556

3863562

3863563

38996_at

74783_r_at

8037166

89863_r_at

A_23_P4679

GE58961

GO:0000122

GO:0000785

GO:0000981

GO:0001227

GO:0003677

GO:0003700

GO:0005515

GO:0005634

GO:0005654

GO:0005694

GO:0005829

GO:0006351

GO:0006355

GO:0006357

GO:0043226

GO:0043565

GO:0140110

HMNXSV003020874

ILMN_1652749

PH_hs_0025778

TC19001570.hg

U15655_at

g5729813_3p_at

g5729813_3p_s_at

g5729813_3p_x_at

Participates

as a component of

ERF:ETS2 Gene [nucleoplasm] (Homo sapiens)

as an input of

Other forms of this molecule

p-T526-ERF [nucleoplasm]

p-T526-ERF [cytosol]

Cross References

RefSeq

XP_016881958.1, NP_001295331.1, NP_001299585.1, NP_001287964.1, NP_006485.2, XP_016881957.1

OpenTargets

ENSG00000105722

HPA

ENSG00000105722-ERF

GeneCards

P50548

Ensembl

ENSG00000105722, ENST00000222329, ENSP00000222329, ENST00000440177, ENSP00000388173

PRO

P50548

Pharos - Targets

P50548

Orphanet

22034

PDB

7JSA, 7JSL

Interactors (14)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P28482 MAPK1	18	MAPK1 [endoplasmic reticulum lumen] (R-HSA-9636293) MAPK1 [azurophil granule lumen] (R-HSA-6799225) MAPK1 [extracellular region] (R-HSA-6806250) MAPK1 [ficolin-1-rich granule lumen] (R-HSA-6800964) p-T185,Y187 MAPK1 E322V [cytosol] (R-HSA-9652797) p-T185,Y187 MAPK1 E322K [cytosol] (R-HSA-9652175) p-T185,Y187 MAPK1 E81K [cytosol] (R-HSA-9652799) p-T185,Y187 MAPK1 S142L [cytosol] (R-HSA-9652808) p-T185,Y187 MAPK1 P58L [cytosol] (R-HSA-9652806) p-T185,Y187 MAPK1 D321V [cytosol] (R-HSA-9652791) p-T185,Y187 MAPK1 D321N [cytosol] (R-HSA-9652785) p-T185,Y187 MAPK1 E322A [cytosol] (R-HSA-9652794) p-T185,Y187 MAPK1 P58G [cytosol] (R-HSA-9652802) p-T185-MAPK1 [cytosol] (R-HSA-9635773) MAPK1 [nucleoplasm] (R-HSA-199960) MAPK1 [cytosol] (R-HSA-59282) p-T185,Y187-MAPK1 [cytosol] (R-HSA-109853) p-T185,Y187-MAPK1 [nucleoplasm] (R-HSA-112354)	0.643	5
UniProt:Q9UGI0 ZRANB1	1	ZRANB1 [cytosol] (R-HSA-6781939)	0.556	3
UniProt:Q08117-2 TLE5			0.556	3
UniProt:Q96EZ8 MCRS1	1	MCRS1 [nucleoplasm] (R-HSA-3321849)	0.556	3
UniProt:Q6FHY5 Q6FHY5			0.556	3
UniProt:Q6UX06 OLFM4	3	OLFM4 [tertiary granule lumen] (R-HSA-6800893) OLFM4 [extracellular region] (R-HSA-6799672) OLFM4 [specific granule lumen] (R-HSA-6799634)	0.527	3
UniProt:Q9H6X2 ANTXR1			0.527	2
UniProt:P61962 DCAF7	2	DCAF7 [nucleoplasm] (R-HSA-8863312) Unfolded DCAF7 [cytosol] (R-HSA-6813821)	0.527	2
UniProt:P27361 MAPK3	6	MAPK3 [endoplasmic reticulum lumen] (R-HSA-9636295) p-T202-MAPK3 [cytosol] (R-HSA-9635775) MAPK3 [nucleoplasm] (R-HSA-73724) MAPK3 [cytosol] (R-HSA-59284) p-T202,Y204-MAPK3 [cytosol] (R-HSA-109842) p-T202,Y204-MAPK3 [nucleoplasm] (R-HSA-112359)	0.527	2
UniProt:Q9Y5F2 PCDBB			0.527	2
UniProt:Q14627 IL13RA2	1	IL13RA2 [extracellular region] (R-HSA-449666)	0.527	2
UniProt:Q9BRK5 CAB45			0.527	2
UniProt:P55345 ANM2			0.527	3
UniProt:Q16853 AOC3	1	AOC3 [plasma membrane] (R-HSA-5696151)	0.527	2

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