Eicosanoids

Stable Identifier
R-HSA-211979
Type
Pathway
Species
Homo sapiens
Compartment
endoplasmic reticulum membrane, endoplasmic reticulum lumen, cytosol
ReviewStatus
5/5
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Eicosanoids
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Arachidonic acid is metabolized via three major enzymatic pathways: cyclooxygenase, lipoxygenase, and cytochrome P450. The cytochrome P450 pathway metabolites are oxygenated metabolites of arachidonic acid.

Literature References
PubMed ID Title Journal Year
7922394 Prostaglandins, thromboxanes, leukotrienes, and cytochrome P-450 metabolites of arachidonic acid

Geisel, J, Cook, JA, Halushka, PV, Reines, HD

New Horiz 1993
15102545 57 varieties: the human cytochromes P450

Lewis, DF

Pharmacogenomics 2004
16584116 Cytochrome P450s and other enzymes in drug metabolism and toxicity

Guengerich, FP

AAPS J 2006
Participants
Events
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as an event of
Event Information
Go Biological Process
icosanoid metabolic process (0006690)
Orthologous Events
Eicosanoids (Bos taurus)
Eicosanoids (Canis familiaris)
Eicosanoids (Danio rerio)
Eicosanoids (Gallus gallus)
Eicosanoids (Mus musculus)
Eicosanoids (Rattus norvegicus)
Eicosanoids (Sus scrofa)
Eicosanoids (Xenopus tropicalis)
Cross References
BioModels Database
Authored
Jassal, B  (2008-05-19)
Reviewed
D'Eustachio, P  (2008-05-28)
Created
Jassal, B  (2008-02-08)
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