Reactome | UBE2V1 [cytosol]

UBE2V1 [cytosol]

Stable Identifier

R-HSA-205753

Type

Protein [EntityWithAccessionedSequence]

Species

Homo sapiens

Compartment

cytosol

Locations in the PathwayBrowser

Expand all

Disease (Homo sapiens)

- Infectious disease (Homo sapiens)
  - Viral Infection Pathways (Homo sapiens)
    - SARS-CoV Infections (Homo sapiens)
      - SARS-CoV-2 Infection (Homo sapiens)
        
        SARS-CoV-2-host interactions (Homo sapiens)
        
        SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
        
        Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
        
        Activated TAK complexes [cytosol] (Homo sapiens)
        
        hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Homo sapiens)
        
        hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Homo sapiens)
        
        UBE2N:UBE2V1 [cytosol] (Homo sapiens)
        
        UBE2V1 [cytosol] (Homo sapiens)

External Reference Information

External Reference

UniProt:Q13404 UBE2V1

Gene Names

UBE2V1, CROC1, UBE2V, UEV1, P/OKcl.19

Chain

initiator methionine:, chain:2-147

Reference Genes

BioGPS Gene:387522 UBE2V1

BioGPS Gene:7335 UBE2V1

COSMIC (genes):UBE2V1 UBE2V1

CTD Gene:387522 UBE2V1

CTD Gene:7335 UBE2V1

dbSNP Gene:387522 UBE2V1

dbSNP Gene:7335 UBE2V1

ENSEMBL:ENSG00000244687 UBE2V1

ENSEMBL_homo_sapiens_GENE:ENSG00000244687.13 UBE2V1

HGNC:12494 UBE2V1

KEGG Gene (Homo sapiens):387522 UBE2V1

KEGG Gene (Homo sapiens):7335 UBE2V1

Monarch:387522 UBE2V1

Monarch:7335 UBE2V1

NCBI Gene:387522 UBE2V1

NCBI Gene:7335 UBE2V1

OMIM:602995 UBE2V1

UCSC:Q13404 UBE2V1

Reference Transcript

Other Identifiers

11715661_a_at

11715662_x_at

11733709_s_at

11735277_a_at

11753660_x_at

16920201

201001_PM_s_at

201001_s_at

201002_PM_s_at

201002_s_at

2706155

2706157

3146338

3895461

3909076

3909077

3909078

3909080

3909095

3909098

3909100

3909101

3909102

3909103

3909104

3909105

4014553

43832_at

7335

8180345

8180402

A_23_P11461

A_23_P218685

A_23_P501996

A_24_P5935

GE476439

GO:0000151

GO:0000209

GO:0005515

GO:0005576

GO:0005615

GO:0005634

GO:0005654

GO:0005737

GO:0005829

GO:0006281

GO:0006282

GO:0006301

GO:0006351

GO:0006355

GO:0023052

GO:0030154

GO:0031371

GO:0032991

GO:0035370

GO:0036211

GO:0043123

GO:0043226

GO:0045893

GO:0051092

GO:0070062

GO:0070534

GO:1902523

GO:1902533

HMNXSV003042628

HMNXSV003044465

Hs.75875.0.S1_3p_a_at

ILMN_1665862

ILMN_1726107

ILMN_2318869

ILMN_2368713

ILMN_2400206

PH_hs_0033028

g1066081_3p_a_at

Participates

as a component of

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Homo sapiens)

Inferred To

Ghost homologue of UBE2V1 [cytosol] (Bos taurus)

Ghost homologue of UBE2V1 [cytosol] (Gallus gallus)

UBE2V1 [cytosol] (Plasmodium falciparum)

UBE2V1 [cytosol] (Sus scrofa)

Uev1A [cytosol] (Drosophila melanogaster)

zgc:123326 [cytosol] (Danio rerio)

spm2 [cytosol] (Schizosaccharomyces pombe)

MMS2 [cytosol] (Saccharomyces cerevisiae)

Ube2v1 [cytosol] (Mus musculus)

LOC119881719 [cytosol] (Canis familiaris)

ENSRNOG00000067007 [cytosol] (Rattus norvegicus)

uev-1 [cytosol] (Caenorhabditis elegans)

ube2v [cytosol] (Dictyostelium discoideum)

Cross References

RefSeq

NP_001244322.1, NP_001244323.1, NP_001027459.1, NP_954595.1, NP_001244325.1, NP_954673.1, NP_071887.1, NP_068823.2

OpenTargets

ENSG00000244687

HPA

ENSG00000244687-UBE2V1

GeneCards

Q13404

Ensembl

ENST00000340309, ENSP00000360739, ENST00000415862, ENSP00000407770, ENST00000371674, ENSG00000244687, ENST00000371657, ENST00000371677, ENSP00000360720, ENSP00000360742, ENSP00000340305

PRO

Q13404

Pharos - Targets

Q13404

PDB

6D6I, 2C2V, 2HLW, 2A4D

Interactors (7)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:P61088 UBE2N	5	Ub-C87-UBE2N [nucleoplasm] (R-HSA-8943013) Ub-C87-UBE2N [cytosol] (R-HSA-8864210) K63polyUb-C87-UBE2N [nucleoplasm] (R-HSA-6790511) UBE2N [nucleoplasm] (R-HSA-5682541) UBE2N [cytosol] (R-HSA-206072)	0.877	20
UniProt:P98170 XIAP	3	XIAP [nucleoplasm] (R-HSA-3322366) K48pUb-XIAP [cytosol] (R-HSA-5675477) XIAP [cytosol] (R-HSA-50849)	0.667	3
UniProt:Q9UNE7 STUB1	1	STUB1 [cytosol] (R-HSA-975970)	0.656	3
UniProt:Q6ZNA4 RNF111	2	RNF111 [cytosol] (R-HSA-975981) RNF111 [nucleoplasm] (R-HSA-2186765)	0.592	2
UniProt:P06396 GSN	7	GSN(200-270) [extracellular region] (R-HSA-976940) GSN [secretory granule lumen] (R-HSA-6801486) GSN [extracellular region] (R-HSA-6806510) GSN [ficolin-1-rich granule lumen] (R-HSA-6801465) GSN(404-782) [cytosol] (R-HSA-350272) GSN(28-403) [cytosol] (R-HSA-201618) GSN [cytosol] (R-HSA-350275)	0.556	3
UniProt:Q14957 GRIN2C	3	GRIN2C [plasma membrane] (R-HSA-419560) p-Y-GRIN2C [plasma membrane] (R-HSA-9612189) GRIN2C [endoplasmic reticulum membrane] (R-HSA-9609761)	0.556	3
UniProt:P11021 HSPA5	6	HSPA5 [extracellular region] (R-HSA-351322) HSPA5 [endoplasmic reticulum lumen] (R-HSA-387190) HSPA5 [endoplasmic reticulum membrane] (R-HSA-351315) HSPA5 [cytosol] (R-HSA-5252115) HSPA5 [nucleoplasm] (R-HSA-5252042) HSPA5 [integral component of lumenal side of endoplasmic reticulum membrane] (R-HSA-985498)	0.556	3

Cite Us!