Reactome | MMS2 [cytosol]

MMS2 [cytosol]

Stable Identifier

R-SCE-205753

Type

Protein [EntityWithAccessionedSequence]

Species

Saccharomyces cerevisiae

Compartment

cytosol

Synonyms

UBE2V1, P53152

Locations in the PathwayBrowser

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Autophagy (Saccharomyces cerevisiae)

- Macroautophagy (Saccharomyces cerevisiae)
  - Selective autophagy (Saccharomyces cerevisiae)
    - Aggrephagy (Saccharomyces cerevisiae)
      - Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Saccharomyces cerevisiae)
        
        PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Saccharomyces cerevisiae)
        
        UBE2N:UBE2V1:PRKN [cytosol] (Saccharomyces cerevisiae)
        
        UBE2N:UBE2V1 [cytosol] (Saccharomyces cerevisiae)
        
        MMS2 [cytosol] (Saccharomyces cerevisiae)
        
        Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Saccharomyces cerevisiae)
        
        UBE2N:UBE2V1:PRKN [cytosol] (Saccharomyces cerevisiae)
        
        UBE2N:UBE2V1 [cytosol] (Saccharomyces cerevisiae)
        
        MMS2 [cytosol] (Saccharomyces cerevisiae)

Immune System (Saccharomyces cerevisiae)

- Adaptive Immune System (Saccharomyces cerevisiae)
  - Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
    - Antigen processing: Ubiquitination & Proteasome degradation (Saccharomyces cerevisiae)
      - Transfer of Ub from E2 to substrate and release of E2 (Saccharomyces cerevisiae)
        
        Ag-substrate:E3:E2:Ub [cytosol] (Saccharomyces cerevisiae)
        
        Ubiquitin:E2 conjugating enzymes [cytosol] (Saccharomyces cerevisiae)
        
        E2 Ubiquitin-conjugating enzyme [cytosol] (Saccharomyces cerevisiae)
        
        MMS2 [cytosol] (Saccharomyces cerevisiae)
        
        E2 Ubiquitin-conjugating enzyme [cytosol] (Saccharomyces cerevisiae)
        
        MMS2 [cytosol] (Saccharomyces cerevisiae)

External Reference Information

External Reference

UniProt:P53152 MMS2

Gene Names

MMS2, YGL087C

Chain

chain:1-137

Reference Genes

BioGPS Gene:852793 MMS2

KEGG:sce:YGL087C MMS2

Monarch:852793 MMS2

NCBI Gene:852793 MMS2

UCSC:P53152 MMS2

Reference Transcript

RefSeq:NM_001180952.1 MMS2

Other Identifiers

852793

GO:0000209

GO:0000329

GO:0004842

GO:0005515

GO:0005575

GO:0005634

GO:0005737

GO:0005829

GO:0006281

GO:0006301

GO:0006605

GO:0008150

GO:0010994

GO:0015031

GO:0016740

GO:0016874

GO:0031371

GO:0044395

GO:0061631

GO:0070534

GO:0070647

Participates

as a candidate of

E2 Ubiquitin-conjugating enzyme [cytosol] (Saccharomyces cerevisiae)

as a component of

UBE2N:UBE2V1 [cytosol] (Saccharomyces cerevisiae)

Other forms of this molecule

MMS2 [cytosol]

Inferred From

UBE2V1 [cytosol] (Homo sapiens)

Cross References

RefSeq

NP_011428.1

ENSEMBL

YGL087C, YGL087C, YGL087C_mRNA

PRO

P53152

PDB

2GMI, 5OJW, 1JAT

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