CD58 binds CD2

Stable Identifier
R-HSA-202714
Type
Reaction [binding]
Species
Homo sapiens
Compartment
plasma membrane
ReviewStatus
5/5
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CD58 binds CD2
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The layout of this reaction may differ from that in the pathway view due to the constraints in pathway layout
The crystal structure of the human CD2-CD58 complex also shows that most of the residues at the interface between these two proteins are charged and form several inter-protein salt bridges.
Literature References
PubMed ID Title Journal Year
17172599 Impact of salt bridges on the equilibrium binding and adhesion of human CD2 and CD58

Bayas, MV, Kearney, A, Avramovic, A, van der Merwe, PA, Leckband, DE

J Biol Chem 2007
14529530 Structural biology of the cell adhesion protein CD2: from molecular recognition to protein folding and design

Wilkins, AL, Yang, W, Yang, JJ

Curr Protein Pept Sci 2003
Participants
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Orthologous Events
CD58 binds CD2 (Bos taurus)
CD58 binds CD2 (Canis familiaris)
CD58 binds CD2 (Gallus gallus)
CD58 binds CD2 (Sus scrofa)
Authored
Ouwehand, WH  (2007-11-12)
Reviewed
Zwaginga, JJ  (2007-11-12)
Created
de Bono, B  (2007-11-11)
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